GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MPO | increases expression | ISO | Mpo (Rattus norvegicus) | 6480464 | CTD | Famotidine results in increased expression of MPO protein | PMID:12023551 | MPO | multiple interactions | ISO | Mpo (Mus musculus) | 6480464 | CTD | Famotidine inhibits the reaction [Acids results in increased activity of MPO protein] | PMID:16091555 | MPO | multiple interactions | ISO | Mpo (Rattus norvegicus) | 6480464 | CTD | Famotidine inhibits the reaction [Ethanol results in increased activity of MPO protein]; Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein]; Famotidine promotes the reaction [Chlorpheniramine results in decreased activity of MPO protein]; Quercetin promotes the reaction [Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein]] | PMID:16437673 PMID:17603938 PMID:18726076 PMID:19034656 PMID:19497431 PMID:20723003 PMID:22257724 PMID:25926722 PMID:27474069 | | ||||||||||||||||||||||
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