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GENE - TERM ANNOTATION REPORT

RGD ID: 1303107
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vkorc1
Name: vitamin K epoxide reductase complex, subunit 1
Acc ID: GO:0042373
Term: vitamin K metabolic process
Definition: The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.
Definition Source(s): GOC:jl, https://en.wikipedia.org/wiki/Vitamin_K, PMID:24489112
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vkorc1acts_upstream_of_or_withinISOVkorc1 (Mus musculus)1624291RGD PMID:15879509

PMID:15879509
Vkorc1involved_inISOVkorc1 (Mus musculus)1624291RGDMGI:5560512 PMID:19492146 PMID:23928358

PMID:19492146 PMID:23928358
Vkorc1involved_inISOVKORC1 (Homo sapiens)1624291RGD PMID:16270630 PMID:33154105

PMID:16270630 PMID:33154105
Vkorc1involved_inIBAMGI:106442 or MGI:1916818 or PANTHER:PTN000376783 or Vkorc1l1 (Rattus norvegicus) or UniProtKB:Q8N0U8 or UniProtKB:Q9BQB61600115GO_CentralGO_REF:0000033

GO_REF:0000033
Vkorc1involved_inIEAInterPro:IPR0424061600115InterProGO_REF:0000002

GO_REF:0000002
Vkorc1involved_inISSUniProtKB:Q9BQB61600115UniProtGO_REF:0000024

GO_REF:0000024
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