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GENE - TERM ANNOTATION REPORT

RGD ID: 12330608
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: IL6ST
Name: interleukin 6 cytokine family signal transducer
Acc ID: GO:0019221
Term: cytokine-mediated signaling pathway
Definition: The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:mah, GOC:signaling, PMID:19295629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL6STinvolved_inIEAUniProtKB:P40189 or UniProtKB:Q00560 or ensembl:ENSMUSP00000138836 or ensembl:ENSP00000370698150520179Ensembl GO_REF:0000107
IL6STinvolved_inIEAGO:0004896150520179GOC GO_REF:0000108
IL6STacts_upstream_of_or_withinISOIl6st (Mus musculus)9068941MGI PMID:7957045

PMID:7957045
IL6STinvolved_inIEAPANTHER:PTHR23036:SF83150520179TreeGrafter GO_REF:0000118
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