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GENE - TERM ANNOTATION REPORT

RGD ID: 12191278
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: MIR451
Name: microRNA mir-451
Acc ID: GO:0016442
Term: RISC complex
Definition: A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.
Definition Source(s): PMID:10749213, PMID:15145345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MIR451part_ofISOMir451a (Mus musculus)9068941MGI PMID:20424607 PMID:22503104 PMID:24205035 PMID:7949730

PMID:20424607 PMID:22503104 PMID:24205035 PMID:7949730
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