Mir451a (microRNA 451a) - Rat Genome Database

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Gene: Mir451a (microRNA 451a) Mus musculus
Analyze
Symbol: Mir451a
Name: microRNA 451a
RGD ID: 1608185
MGI Page MGI
Description: Acts upstream of or within several processes, including cellular hyperosmotic salinity response; cellular response to estrogen stimulus; and sensory perception of sound. Located in extracellular exosome. Part of RISC complex. Is expressed in aorta; bone marrow; liver; and liver lobe. Orthologous to human MIR451A (microRNA 451a).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-451a; Mir451; Mirn; Mirn451; mmu-mir-4; mmu-mir-451; mmu-mir-451a
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,963,996 - 77,964,067 (+)NCBIGRCm39mm39
GRCm39 Ensembl1177,963,996 - 77,964,067 (+)Ensembl
GRCm381178,073,170 - 78,073,241 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,073,170 - 78,073,241 (+)EnsemblGRCm38mm10GRCm38
MGSCv371177,886,672 - 77,886,743 (+)NCBIGRCm37mm9NCBIm37
Celera1185,572,772 - 85,572,843 (+)NCBICelera
Cytogenetic Map11B5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Additional References at PubMed
PMID:7949730   PMID:15891114   PMID:16274478   PMID:16381832   PMID:17028171   PMID:17604727   PMID:18303114   PMID:18594913   PMID:18791161   PMID:19727952   PMID:20215419   PMID:20413612  
PMID:20424607   PMID:20513743   PMID:20548288   PMID:20679397   PMID:20679398   PMID:20699384   PMID:21037258   PMID:21267068   PMID:21364282   PMID:21371421   PMID:21464222   PMID:21791432  
PMID:21857976   PMID:22144232   PMID:22187428   PMID:22354898   PMID:22503104   PMID:22844086   PMID:22844503   PMID:23169590   PMID:23646144   PMID:23705032   PMID:24205035   PMID:24937656  
PMID:25287330   PMID:25542822   PMID:25937278   PMID:25957914   PMID:26573748   PMID:27264074   PMID:27495223   PMID:28120198   PMID:28378118   PMID:28982131   PMID:29269522   PMID:29604329  
PMID:29720118   PMID:30069596   PMID:30218791   PMID:30462722   PMID:30576241   PMID:30578296   PMID:30872181   PMID:30925184   PMID:30971389   PMID:31355248   PMID:31399524   PMID:31541885  
PMID:32159972   PMID:32234673   PMID:32273567   PMID:32321512   PMID:32643864   PMID:33319407  


Genomics

Comparative Map Data
Mir451a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,963,996 - 77,964,067 (+)NCBIGRCm39mm39
GRCm39 Ensembl1177,963,996 - 77,964,067 (+)Ensembl
GRCm381178,073,170 - 78,073,241 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,073,170 - 78,073,241 (+)EnsemblGRCm38mm10GRCm38
MGSCv371177,886,672 - 77,886,743 (+)NCBIGRCm37mm9NCBIm37
Celera1185,572,772 - 85,572,843 (+)NCBICelera
Cytogenetic Map11B5NCBI
MIR451A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1728,861,369 - 28,861,440 (-)EnsemblGRCh38hg38GRCh38
GRCh381728,861,369 - 28,861,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371727,188,387 - 27,188,458 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361724,212,512 - 24,212,583 (-)NCBINCBI36hg18NCBI36
Celera1724,047,811 - 24,047,882 (-)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1723,396,677 - 23,396,748 (-)NCBIHuRef
CHM1_11727,250,901 - 27,250,972 (-)NCBICHM1_1
Mir451a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21062,961,520 - 62,961,591 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1062,961,520 - 62,961,591 (+)Ensembl
Rnor_6.01065,291,204 - 65,291,275 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,291,204 - 65,291,275 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01066,340,853 - 66,340,924 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1061,939,610 - 61,939,681 (+)NCBICelera
Cytogenetic Map10q25NCBI
MIR451
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1943,030,863 - 43,030,931 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl943,030,863 - 43,030,931 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha942,186,005 - 42,186,073 (-)NCBI
ROS_Cfam_1.0943,848,583 - 43,848,651 (-)NCBI
UMICH_Zoey_3.1942,632,123 - 42,632,191 (-)NCBI
UNSW_CanFamBas_1.0942,924,146 - 42,924,214 (-)NCBI
UU_Cfam_GSD_1.0943,002,786 - 43,002,854 (-)NCBI
MIR451
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1245,088,808 - 45,088,872 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11245,088,808 - 45,088,872 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21247,177,114 - 47,177,178 (+)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117384671582178599Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
4141365Ltxs3_mlethal factor toxin susceptibility 3 (mouse)Not determined117768304780855532Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117768304799486994Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mycmmu-miR-451aMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI21464222
Megf9mmu-miR-451aMirtarbaseexternal_infoSequencingFunctional MTI (Weak)19536157
Cab39mmu-miR-451aOncomiRDBexternal_infoNANA22179124
Mifmmu-miR-451aOncomiRDBexternal_infoNANA21948564
Rab14mmu-miR-451aOncomiRDBexternal_infoNANA21358675
Cab39mmu-miR-451aOncomiRDBexternal_infoNANA20227367
Mifmmu-miR-451aOncomiRDBexternal_infoNANA19318487

Predicted Targets
Summary Value
Count of predictions:2075
Count of gene targets:1311
Count of transcripts:1947
Interacting mature miRNAs:mmu-miR-451a
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000093557
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1177,963,996 - 77,964,067 (+)Ensembl
GRCm38.p6 Ensembl1178,073,170 - 78,073,241 (+)Ensembl
RefSeq Acc Id: NR_029971
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391177,963,996 - 77,964,067 (+)NCBI
GRCm381178,073,170 - 78,073,241 (+)ENTREZGENE
MGSCv371177,886,672 - 77,886,743 (+)RGD
Celera1185,572,772 - 85,572,843 (+)RGD
cM Map11 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3619412 AgrOrtholog
Ensembl Genes ENSMUSG00000070065 Ensembl
  ENSMUSG00000118889 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000093557 ENTREZGENE
MGD MGI:3619412 ENTREZGENE
miRBase MI0001730 ENTREZGENE
NCBI Gene 723870 ENTREZGENE
PhenoGen Mir451a PhenoGen
RNAcentral URS00002E857A RNACentral
  URS000062EC78 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-05-27 Mir451a  microRNA 451a  Mir451  microRNA 451  Symbol and/or name change 5135510 APPROVED