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GENE - TERM ANNOTATION REPORT

RGD ID: 12160870
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: HTR2C
Name: 5-hydroxytryptamine receptor 2C
Acc ID: GO:0007208
Term: phospholipase C-activating serotonin receptor signaling pathway
Definition: A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by serotonin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:dph, GOC:mah, GOC:signaling, GOC:tb
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HTR2C ISOHtr2c (Rattus norvegicus)9068941RGD PMID:12435801 REF_RGD_ID:1598460
HTR2Cinvolved_inIEAUniProtKB:P28335 or UniProtKB:P34968 or ensembl:ENSMUSP00000094021 or ensembl:ENSP00000276198150520179Ensembl GO_REF:0000107
HTR2Cinvolved_inIBAMGI:96281 or PANTHER:PTN008398567 or Htr2c (Rattus norvegicus) or Htr2a (Rattus norvegicus) or UniProtKB:P28335 or UniProtKB:P41595150520179GO_Central GO_REF:0000033
HTR2Cinvolved_inISSUniProtKB:P34968150520179UniProt GO_REF:0000024
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