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GENE - TERM ANNOTATION REPORT

RGD ID: 11708998
Species: Pan paniscus
RGD Object: Gene
Symbol: AHR
Name: aryl hydrocarbon receptor
Acc ID: DOID:9007383
Term: Chemical and Drug Induced Liver Injury
Definition: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
Definition Source(s): MESH:D056486
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AHR ISOAhr (Rattus norvegicus)9068941RGDmRNA:decreased expression:liver (rat)PMID:28959666 REF_RGD_ID:401794432
AHR ISOAHR (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanism|therapeuticPMID:21890736 PMID:34848246
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