GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | ISO | Tnf (Rattus norvegicus) | 15017096 | RGD | estriol enhances the reaction [lipopolysaccharide increases expression of Tnf mRNA in liver and protein in serum] | | Tnf | multiple interactions | EXP | | 6480464 | CTD | Estriol affects the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Estriol inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased abundance of Nitric Oxide]; Estriol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Estriol promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Tamoxifen inhibits the reaction [Estriol promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]] | PMID:11063824 PMID:8979148 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | Estriol inhibits the reaction [TNF protein affects the localization of RELA protein]; Estriol inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; Estriol inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; fulvestrant inhibits the reaction [Estriol inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]] | PMID:12547825 | | ||||||||||||||||||||||
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