GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | multiple interactions | EXP | | 6480464 | CTD | [Drugs, Chinese Herbal co-treated with Selenium] results in decreased expression of TNF mRNA; [Selenium co-treated with Lipopolysaccharides co-treated with IL4 protein] results in decreased expression of TNF mRNA | PMID:21775527 PMID:24626144 | Tnf | increases expression | ISO | TNF (Homo sapiens) | 6480464 | CTD | Selenium results in increased expression of TNF mRNA | PMID:17293063 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | [Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of TNF mRNA; Selenium affects the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; Selenium inhibits the reaction [Cadmium results in increased expression of and results in increased secretion of TNF protein]; Selenium inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; Selenium promotes the reaction [T-2 Toxin results in increased expression of TNF protein] | PMID:10802230 PMID:18196609 PMID:21481475 PMID:29028684 | Tnf | multiple interactions | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Selenium affects the reaction [Mercuric Chloride results in decreased expression of TNF protein] | PMID:15862027 PMID:26089086 | | ||||||||||||||||||||||
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