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GENE - TERM ANNOTATION REPORT

5 Annotations Found.

An association has been curated linking Fgfr2 and prostate cancer in Ictidomys tridecemlineatus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Automated assignment of GO, PW and RDO ISO annotations across species
  • The annotation has been inferred from sequence orthology with FGFR2 (Homo sapiens)
  • 776 RGD objects have been annotated to prostate cancer  (DOID:10283)
  • 0 papers in RGD have been used to annotate Fgfr2
  • Qualifier: disease_progression
  • Curation Notes: mRNA:decreased expression:prostate:isoforms IIIb and IIIc, decrease in IIIb associated with progression to androgen-independence
  • Original References(s): PMID:12111699 REF_RGD_ID:2289728


    • An association has been curated linking Fgfr2 and prostate cancer in Ictidomys tridecemlineatus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Automated assignment of GO, PW and RDO ISO annotations across species
  • The annotation has been inferred from sequence orthology with FGFR2 (Homo sapiens)
  • 776 RGD objects have been annotated to prostate cancer  (DOID:10283)
  • 0 papers in RGD have been used to annotate Fgfr2
  • Curation Notes: mRNA:alternative form:prostate:switch from isoform IIIb to IIIc
  • Original References(s): PMID:11170144 REF_RGD_ID:2289746


    • An association has been curated linking Fgfr2 and prostate cancer in Ictidomys tridecemlineatus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Automated assignment of GO, PW and RDO ISO annotations across species
  • The annotation has been inferred from sequence orthology with FGFR2 (Homo sapiens)
  • 776 RGD objects have been annotated to prostate cancer  (DOID:10283)
  • 0 papers in RGD have been used to annotate Fgfr2
  • Curation Notes: mRNA:increased expression:prostate gland
  • Original References(s): PMID:9285567 REF_RGD_ID:2289086


    • An association has been curated linking Fgfr2 and prostate cancer in Ictidomys tridecemlineatus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Automated assignment of GO, PW and RDO ISO annotations across species
  • The annotation has been inferred from sequence orthology with FGFR2 (Homo sapiens)
  • 776 RGD objects have been annotated to prostate cancer  (DOID:10283)
  • 0 papers in RGD have been used to annotate Fgfr2
  • Qualifier: no_association
  • Curation Notes: DNA:mutation,polymorphism:exons:no mutations or polymorphisms found in patient or cell line DNA to explain changes in expression seen in other studies
  • Original References(s): PMID:11069376 REF_RGD_ID:2289845


    • An association has been curated linking Fgfr2 and prostate cancer in Ictidomys tridecemlineatus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Automated assignment of GO, PW and RDO ISO annotations across species
  • The annotation has been inferred from sequence orthology with Fgfr2 (Rattus norvegicus)
  • 776 RGD objects have been annotated to prostate cancer  (DOID:10283)
  • 0 papers in RGD have been used to annotate Fgfr2
  • Curation Notes: mRNA:splice variant::shift from Fgfr2IIIb to Fgfr2IIIc in malignancy, restoration of Fgfr2IIIb slows growth
  • Original References(s): PMID:9537256 REF_RGD_ID:2289859


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