Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - TERM ANNOTATION REPORT

4 Annotations Found.

An association has been curated linking Tshr and congenital hypothyroidism in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with TSHR (Homo sapiens) [(EXP) inferred from experiment]
  • 233 RGD objects have been annotated to congenital hypothyroidism  (DOID:0050328)
  • 32 papers in RGD have been used to annotate Tshr
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:12629076


    • An association has been curated linking Tshr and congenital hypothyroidism in Rattus norvegicus.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Yang J, etal., Sci Rep. 2018 Mar 5;8(1):4004. doi: 10.1038/s41598-018-22405-7.
  • 29 additional annotations were made from Yang J, etal., Sci Rep. 2018 Mar 5;8(1):4004. doi: 10.1038/s41598-018-22405-7.
  • 233 RGD objects have been annotated to congenital hypothyroidism  (DOID:0050328)
  • 32 papers in RGD have been used to annotate Tshr


    • An association has been curated linking Tshr and congenital hypothyroidism in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with TSHR (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 233 RGD objects have been annotated to congenital hypothyroidism  (DOID:0050328)
  • 32 papers in RGD have been used to annotate Tshr
  • Curation Notes: ClinVar Annotator: match by term: Congenital hypothyroidism
  • Original References(s): PMID:11442002 PMID:15693879 PMID:16756469 PMID:17526952 PMID:19158199 PMID:19506388 PMID:21677043 PMID:21707688 PMID:21714469 PMID:22405933 PMID:22876533 PMID:23926367 PMID:24033266 PMID:24895636 PMID:25741868 PMID:26709262 PMID:27084275 PMID:27637299 PMID:28444304 PMID:28455095 PMID:28492532 PMID:30083029 PMID:31356790


    • An association has been curated linking Tshr and congenital hypothyroidism in Rattus norvegicus.        

  • The association was inferred from sequence or structural similarity (ISS)
    		•  
  • The annotation was made from RGD automated import pipeline for MGI gene-to-disease annotations
  • The annotation has been inferred from sequence or structural similarity with Tshr (Mus musculus) [(IAGP) inferred by association of genotype and phenotype]
  • 233 RGD objects have been annotated to congenital hypothyroidism  (DOID:0050328)
  • 32 papers in RGD have been used to annotate Tshr


    • Go Back to source page   Continue to Ontology report