Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TSHR (thyroid stimulating hormone receptor) Homo sapiens
Analyze
Symbol: TSHR
Name: thyroid stimulating hormone receptor
Description: Exhibits thyroid-stimulating hormone receptor activity. Involved in G protein-coupled receptor signaling pathway; cell surface receptor signaling pathway; and cellular response to organonitrogen compound. Localizes to basolateral plasma membrane and receptor complex. Implicated in Graves' disease; cardiomyopathy; congenital nongoitrous hypothyroidism 1; and mitral valve prolapse.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CHNG1; hTSHR-I; LGR3; MGC75129; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2; thyroid stimulating hormone, receptor; thyroid-stimulating hormone receptor; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; TSH receptor; TSH-R
Orthologs:
Mus musculus (house mouse) : Tshr (thyroid stimulating hormone receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tshr (thyroid stimulating hormone receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tshr (thyroid stimulating hormone receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : TSHR (thyroid stimulating hormone receptor)
Canis lupus familiaris (dog) : TSHR (thyroid stimulating hormone receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tshr (thyroid stimulating hormone receptor)
Sus scrofa (pig) : TSHR (thyroid stimulating hormone receptor)
Chlorocebus sabaeus (African green monkey) : TSHR (thyroid stimulating hormone receptor)
Heterocephalus glaber (naked mole-rat) : Tshr (thyroid stimulating hormone receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1480,954,989 - 81,146,302 (+)EnsemblGRCh38hg38GRCh38
GRCh381480,954,989 - 81,146,306 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371481,421,333 - 81,612,646 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361480,491,622 - 80,682,399 (+)NCBINCBI36hg18NCBI36
Build 341480,491,678 - 80,680,525NCBI
Celera1461,461,769 - 61,652,548 (+)NCBI
Cytogenetic Map14q31.1NCBI
HuRef1461,589,584 - 61,780,253 (+)NCBIHuRef
CHM1_11481,362,344 - 81,553,060 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on TSHR
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737021
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-06-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.