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GENE - TERM ANNOTATION REPORT

5 Annotations Found.

An association has been curated linking AKR1B1 and diabetic retinopathy in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Vinores SA, etal., Exp Eye Res. 1993 Dec;57(6):723-35.
  • The annotation has been inferred from sequence orthology with Akr1b1 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 4 additional annotations were made from Vinores SA, etal., Exp Eye Res. 1993 Dec;57(6):723-35.
  • 468 RGD objects have been annotated to diabetic retinopathy  (DOID:8947)
  • 37 papers in RGD have been used to annotate AKR1B1
  • Curation Notes: protein:increased expression:retinal astrocyte (rat)


    • An association has been curated linking AKR1B1 and diabetic retinopathy in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Olmos P, etal., Diabetes Res Clin Pract. 2006 Nov;74(2):175-82. Epub 2006 May 15.
  • 2 additional annotations were made from Olmos P, etal., Diabetes Res Clin Pract. 2006 Nov;74(2):175-82. Epub 2006 May 15.
  • 468 RGD objects have been annotated to diabetic retinopathy  (DOID:8947)
  • 37 papers in RGD have been used to annotate AKR1B1
  • Qualifier: susceptibility
  • Curation Notes: associated with Diabetes Mellitus, Type 2;DNA:snp:promoter:g.-106C>T (human)


    • An association has been curated linking AKR1B1 and diabetic retinopathy in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Sun W, etal., Diabetes. 2006 Oct;55(10):2757-62.
  • The annotation has been inferred from sequence orthology with Akr1b1 (Rattus norvegicus) [(IDA) inferred from direct assay]
  • 2 additional annotations were made from Sun W, etal., Diabetes. 2006 Oct;55(10):2757-62.
  • 468 RGD objects have been annotated to diabetic retinopathy  (DOID:8947)
  • 37 papers in RGD have been used to annotate AKR1B1
  • Curation Notes: associated with Diabetes Mellitus, Experimental


    • An association has been curated linking AKR1B1 and diabetic retinopathy in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Balasubbu S, etal., BMC Med Genet. 2010 Nov 10;11:158. doi: 10.1186/1471-2350-11-158.
  • 5 additional annotations were made from Balasubbu S, etal., BMC Med Genet. 2010 Nov 10;11:158. doi: 10.1186/1471-2350-11-158.
  • 468 RGD objects have been annotated to diabetic retinopathy  (DOID:8947)
  • 37 papers in RGD have been used to annotate AKR1B1
  • Qualifier: no_association
  • Curation Notes: associated with Diabetes Mellitus, Type 2;DNA:promoter:repeat:g.-2008(AC)n (rs35839483) (human)


    • An association has been curated linking AKR1B1 and diabetic retinopathy in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Abhary S, etal., Diabetes. 2009 Sep;58(9):2137-47. doi: 10.2337/db09-0059. Epub 2009 Jul 8.
  • 2 additional annotations were made from Abhary S, etal., Diabetes. 2009 Sep;58(9):2137-47. doi: 10.2337/db09-0059. Epub 2009 Jul 8.
  • 468 RGD objects have been annotated to diabetic retinopathy  (DOID:8947)
  • 37 papers in RGD have been used to annotate AKR1B1
  • Qualifier: susceptibility
  • Curation Notes: associated with Diabetes Mellitus;DNA:repeats, snp:promoter:multiple (human)


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