RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: diabetic retinopathy
Accession: DOID:8947
browse the term
Definition: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
Synonyms: exact_synonym: Diabetic Proliferative Retinopathy; Diabetic Retinopathies; retinal abnormality - diabetes-related
primary_id: MESH:D003930
alt_id: RDO:0005356; RDO:0008910; RDO:0009673
xref: ICD9CM:362.0 ; NCI:C34538
For additional species annotation, visit the
Alliance of Genome Resources .
G
Ace
angiotensin I converting enzyme
susceptibility no_association
ISO
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum (human) associated with Diabetes Mellitus, Type 2;DNA:snp:exon:g.2350G>A (rs4343) (human) associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human) associated with Diabetes Mellitus, Type 2;DNA:deletion:intron:IVS16+1464-1751del (human)
GAD RGD
PMID:15118671 , PMID:2157294 , PMID:23065222 , PMID:7729604 , PMID:11106834
RGD:1331525 , RGD:8142360 , RGD:7829794 , RGD:7829780 , RGD:7829783
NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
G
Ace2
angiotensin I converting enzyme 2
treatment
ISO
associated with Diabetes Mellitus, Experimental human gene in a mouse model CTD Direct Evidence: therapeutic
CTD
PMID:31380462 , PMID:21792177 , PMID:31380462
RGD:8548900 , RGD:40818278
NCBI chr X:32,050,734...32,095,860
Ensembl chr X:32,049,931...32,096,016
G
Acp1
acid phosphatase 1
ISO
associated with Diabetes Mellitus, Insulin-Dependent
RGD
PMID:12495297
RGD:2313184
NCBI chr 6:49,836,064...49,851,714
Ensembl chr 6:49,836,075...49,851,714
G
Adipoq
adiponectin, C1Q and collagen domain containing
disease_progression
ISO
associated with Diabetes Mellitus, Type 2;DNA:SNP: :g.45T>G (human) associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
RGD
PMID:24655058 , PMID:17970779
RGD:8694412 , RGD:8694475
NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
G
Adm
adrenomedullin
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
RGD
PMID:19216096
RGD:2313312
NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
G
Adrb3
adrenoceptor beta 3
ISO
associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.W64R rs4994 (human)
RGD
PMID:9313761
RGD:5684400
NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
G
Ager
advanced glycosylation end product-specific receptor
no_association treatment severity susceptibility
ISO IDA IEP
associated with Diabetes Mellitus, Type 2;DNA:polymorphisms: :p.G82S, 1704G>T, 2184A>G (human) associated with Diabetes Mellitus, Experimental associated with Diabetes Mellitus, Type 2;DNA:SNP: :2245G>A (human) associated with Diabetes Mellitus, Type 2;DNA:SNP:promoter:-429T>C (human) associated with Diabetes Mellitus, Type 2;DNA:SNP:promoter:-374T>A, - 429T>C (human) associated with Diabetes Mellitus, Type 2;DNA:SNP:promoter:-374T>A (human) associated with Diabetes Mellitus, Type 1;DNA:SNP:promoter:-374T>A (human) protein:increased expression:retina inner nuclear layer, retinal ganglion cell (rat) associated with Diabetes Mellitus, Type 2;DNA:polymorphisms:promoter, cds, intron:g.-443T>C, p.G82S, g.1704G>T (rs1800625, rs2070600, rs184003) (human) associated with Diabetes Mellitus, Type 2;DNA:missense mutation, snp, haplotype:cds, intron:p.G82S, g.1704G>T (human) associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
GAD RGD
PMID:15118671 , PMID:22427038 , PMID:22171162 , PMID:22116960 , PMID:11375354 , PMID:14704946 , PMID:16969646 , PMID:16969646 , PMID:23146804 , PMID:23587252 , PMID:22475522 , PMID:19542745 , PMID:23091285
RGD:1331525 , RGD:8695983 , RGD:8695979 , RGD:8695967 , RGD:8695966 , RGD:8695965 , RGD:8695958 , RGD:8695958 , RGD:7244369 , RGD:7244248 , RGD:7244176 , RGD:7244175 , RGD:7244174
NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
G
Agt
angiotensinogen
treatment
ISO IMP
associated with Diabetes Mellitus, Type 1;DNA:polymorphism: :p.M235T (human) CTD Direct Evidence: marker/mechanism associated with Diabetes Mellitus, Experimental
CTD
PMID:15387897 , PMID:10862638 , PMID:21792177
RGD:8548872 , RGD:8548900
NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
G
Agtr1a
angiotensin II receptor, type 1a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16601577
NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
G
Akr1b1
aldo-keto reductase family 1 member B
no_association susceptibility
IDA IEP ISO
associated with Diabetes Mellitus, Experimental protein:increased expression:retinal astrocyte (rat) associated with Diabetes Mellitus, Type 2;DNA:promoter:repeat:g.-2008(AC)n (rs35839483) (human) associated with Diabetes Mellitus, Type 2;DNA:snp:promoter:g.-106C>T (human) associated with Diabetes Mellitus;DNA:repeats, snp:promoter:multiple (human)
RGD
PMID:17003340 , PMID:8150024 , PMID:21067572 , PMID:16701918 , PMID:19587357
RGD:1626080 , RGD:8548684 , RGD:8548676 , RGD:8548668 , RGD:8548640
NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
G
Akt1
AKT serine/threonine kinase 1
IEP
mRNA, protein:increased expression:retina
RGD
PMID:31759996
RGD:41410819
NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
G
Ang
angiogenin
ISO
associated with Diabetes Mellitus, Type 2;protein:decreased tyrosine phosphorylation:vitreous humor
RGD
PMID:18978347
RGD:2307061
NCBI chr15:28,022,926...28,028,636
G
Angpt1
angiopoietin 1
ISO
associated with Diabetes Mellitus, Experimental
RGD
PMID:12000720
RGD:2313818
NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
G
Angpt2
angiopoietin 2
IEP IDA
protein:increased expression:retina (rat)
RGD
PMID:16520919 , PMID:16520919
RGD:2314216 , RGD:2314216
NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
G
Aoc3
amine oxidase, copper containing 3
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
RGD
PMID:11522499
RGD:2313826
NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
G
Apoa4
apolipoprotein A4
ISO
protein:increased expression:vitreous humor (human)
RGD
PMID:19081814
RGD:5685692
NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
G
Apob
apolipoprotein B
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent
RGD
PMID:19448981
RGD:2313976
NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
G
Apoc3
apolipoprotein C3
severity
ISO
protein:increased expression:serum
RGD
PMID:15642486
RGD:2306768
NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
G
Apoe
apolipoprotein E
susceptibility no_association
ISO
associated with Diabetic Mellitus type 2;DNA:polymorphism:exon:
RGD
PMID:16862278 , PMID:11495633
RGD:7771557 , RGD:7771553
NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
G
Apoh
apolipoprotein H
ISO
protein:increased expression:vitreous humor
RGD
PMID:18695102
RGD:2313982
NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
G
Aqp4
aquaporin 4
IMP
RGD
PMID:22449442
RGD:8695996
NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
G
Bdkrb1
bradykinin receptor B1
treatment
IEP
associated with Diabetes Mellitus, Experimental
RGD
PMID:18311190
RGD:2313334
NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
G
Bdnf
brain-derived neurotrophic factor
IEP
associated with Diabetes Mellitus, Experimental;protein:decreased expression:retina:
RGD
PMID:15331553
RGD:8655657
NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
G
Casp3
caspase 3
IEP ISO
associated with Diabetes Mellitus, Experimental;protein:increased expresssion:retina CTD Direct Evidence: marker/mechanism associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD
PMID:20654064 , PMID:19187597 , PMID:19013511
RGD:2311444 , RGD:2311448
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
G
Casp9
caspase 9
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased activation:retina
RGD
PMID:18369072
RGD:2311244
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
G
Cat
catalase
IEP
protein:decreased expression:retina
RGD
PMID:21314438
RGD:5130875
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
G
Ccl2
C-C motif chemokine ligand 2
IEP
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:retina (rat)
RGD
PMID:23010641
RGD:8548887
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
G
Ccl5
C-C motif chemokine ligand 5
severity
ISO
protein:increased expression:serum associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased tyrosine phosphorylation:vitreous humor
RGD
PMID:16249511 , PMID:18978347
RGD:2307104 , RGD:2307061
NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
G
Ccn2
cellular communication network factor 2
IEP
associated with Diabetes Mellitus, Experimental; mRNA:increased expression:retina (rat)
RGD
PMID:19450451
RGD:2314507
NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
G
Ccr5
C-C motif chemokine receptor 5
ISO
associated with Diabetes Mellitus, Experimental
RGD
PMID:22677420
RGD:8551828
NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
G
Cd34
CD34 molecule
IEP
mRNA, protein:increased expression:retina
RGD
PMID:31759996
RGD:41410819
NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
G
Cd59
CD59 molecule
IEP
protein:decreased expression:retina
RGD
PMID:12453906
RGD:1600487
NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
G
Cfb
complement factor B
no_association
ISO
associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs1048709 (human) associated with Diabetes Mellitus, Type 2;DNA:SNP: :rs537160, rs4151657, rs2072633 (human)
RGD
PMID:23864767 , PMID:23864767
RGD:7365019 , RGD:7365019
NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066 Ensembl chr20:4,536,203...4,561,066
G
Cfh
complement factor H
ISO
associated with Diabetes Mellitus, Type 2; DNA:SNP: :rs800292(human) associated with Diabetes Mellitus, Type 1;DNA:SNP: :rs1410996(human)
RGD
PMID:23864767 , PMID:23296223
RGD:7365019 , RGD:7365023
NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
G
Cldn1
claudin 1
treatment
IEP
RGD
PMID:25685822
RGD:11341734
NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
G
Clu
clusterin
treatment
ISO
associated with Diabetes Mellitus, Experimental
RGD
PMID:19875648
RGD:9068395
NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
G
Crp
C-reactive protein
ISO
protein:increased expression:serum: CTD Direct Evidence: marker/mechanism
CTD
PMID:20012460 , PMID:20012460
RGD:8547537
NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
G
Cxcl10
C-X-C motif chemokine ligand 10
ISO
RGD
PMID:17194635
RGD:2311361
NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
G
Cxcl12
C-X-C motif chemokine ligand 12
severity
ISO
protein:increased expression:vitreous humor
RGD
PMID:15630447
RGD:2306559
NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
G
Cyba
cytochrome b-245 alpha chain
IEP
associated with Diabetes Mellitus, Experimental
RGD
PMID:19685553
RGD:2317854
NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
G
Edn1
endothelin 1
ISO IEP
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism:exon:p.K198N (human) mRNA:increased expression:retina (rat) associated with Diabetes Mellitus, Insulin-Dependent;protein:increased secretion:plasma
RGD
PMID:18806884 , PMID:20628425 , PMID:19293263
RGD:2313281 , RGD:9068929 , RGD:2313279
NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
G
Egfr
epidermal growth factor receptor
treatment
ISO
protein:increased expression:retina associated with Diabetes Mellitus, Experimental
RGD
PMID:7947554 , PMID:23831329
RGD:1580957 , RGD:10059675
NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
G
Eln
elastin
ISO
RGD
PMID:11707314
RGD:9585734
NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
G
Eng
endoglin
ISO
associated with Diabetes Mellitus, Insulin-Dependent; protein:increased expression:plasma,vitreous body
RGD
PMID:16202216
RGD:1580961
NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
G
Ep300
E1A binding protein p300
IMP
associated with Diabetes Mellitus, Experimental
RGD
PMID:21885871
RGD:7349382
NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
G
Epo
erythropoietin
susceptibility
ISO
protein:increased expression:serum,vitreous body associated with Diabetes Mellitus, Experimental DNA:snp:promoter:-1125T>G(rs1617640)(human)
RGD
PMID:18670462 , PMID:24508793 , PMID:18235022 , PMID:18458324
RGD:2313837 , RGD:10400906 , RGD:2313890 , RGD:2313838
NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
G
F13a1
coagulation factor XIII A1 chain
ISO
protein:increased expression:optic choroid vascular plexus:
RGD
PMID:11375345
RGD:8693344
NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
G
F3
coagulation factor III, tissue factor
ISO
protein:increased expression:aqueous humor,serum
RGD
PMID:12417540
RGD:2313865
NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
G
F7
coagulation factor VII
ISO
associated with Diabetes Mellitus, Insulin-Dependent; protein:increased activity:plasma (human)
RGD
PMID:10837382
RGD:2312398
NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
G
Fgf2
fibroblast growth factor 2
ISO IEP
associated with Pregnancy in Diabetics DNA:polymorphism:intron:g.754C>G(human) DNA:polymorphism:promotor:g.-553T>A(human) associated with Diabetes Mellitus, Experimental
RGD
PMID:9141532 , PMID:17997184 , PMID:18279437 , PMID:14975211
RGD:2315885 , RGD:2315845 , RGD:2315844 , RGD:2315875
NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
G
Flt1
Fms related receptor tyrosine kinase 1
treatment
ISO IEP
RGD
PMID:17143550 , PMID:18174522
RGD:2313721 , RGD:10402119
NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
G
Fuca1
alpha-L-fucosidase 1
IEP
associated with Diabetes Mellitus, Experimental;protein:increased activity:retina
RGD
PMID:10353622
RGD:2315932
NCBI chr 5:154,269,296...154,286,545
Ensembl chr 5:154,269,118...154,286,544
G
Gad2
glutamate decarboxylase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21412422
NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
IEP
associated with Diabetes Mellitus, Experimental
RGD
PMID:18852331
RGD:2315975
NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
G
Gc
GC, vitamin D binding protein
ISO
protein:increased expression:vitreous body
RGD
PMID:16080911
RGD:2315548
NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
G
Ggt1
gamma-glutamyltransferase 1
ISO
associated with Diabetes Mellitus,Insulin-Dependent;protein:increased activity:serum
RGD
PMID:11311965
RGD:2315614
NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
G
Gh1
growth hormone 1
ISO
RGD
PMID:3183302
RGD:2315688
NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
G
Glo1
glyoxalase 1
no_association
ISO
DNA:SNP:promoter:-7C>T (human)
RGD
PMID:21738003 , PMID:21738003
RGD:7242569 , RGD:7242569
NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
G
Gstm1
glutathione S-transferase mu 1
susceptibility
ISO
associated with Diabetes Mellitus, Type 1;DNA:deletion:cds (human)
RGD
PMID:19752172
RGD:7495818
NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
G
Gstt1
glutathione S-transferase theta 1
disease_progression no_association
ISO
associated with Diabetes Mellitus, Type 2;DNA:deletion:cds (human) associated with Diabetes Mellitus, Type 1;DNA:deletion:cds (human)
RGD
PMID:15927971 , PMID:19752172
RGD:2306630 , RGD:7495818
NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
G
Hfe
homeostatic iron regulator
ISO
associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.C282Y (human)
RGD
PMID:15347835
RGD:8694362
NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
G
Hgf
hepatocyte growth factor
disease_progression
ISO
associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:serum
RGD
PMID:18335393 , PMID:15525877
RGD:2313565 , RGD:8548539
NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
G
Hif1a
hypoxia inducible factor 1 subunit alpha
severity treatment
ISO IDA IEP
protein:increased expression:retina, vascular endothelial cell (human) associated with Diabetes Mellitus, Experimental associated with Diabetes Mellitus, Experimental;protein:increased expression:retina (rat)
RGD
PMID:17229797 , PMID:20515763 , PMID:22110070
RGD:8694462 , RGD:8696025 , RGD:7364887
NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
G
Hras
HRas proto-oncogene, GTPase
IDA
RGD
PMID:14988264
RGD:1358731
NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
G
Icam1
intercellular adhesion molecule 1
treatment
ISO IEP
CTD Direct Evidence: therapeutic associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.K469E (human)
CTD
PMID:10485912 , PMID:18834676 , PMID:25066112 , PMID:18942221
RGD:2313472 , RGD:11354984 , RGD:2313471
NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
G
Igf1
insulin-like growth factor 1
susceptibility
ISO
protein:decreased expression:serum
RGD
PMID:16873705 , PMID:17194636
RGD:1598424 , RGD:2313764
NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
G
Igf1r
insulin-like growth factor 1 receptor
disease_progression
IEP
mRNA:increased expression:retina:
RGD
PMID:12781065
RGD:10046008
NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
G
Il10
interleukin 10
susceptibility
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased tyrosine phosphorylation:vitreous humor associated with Diabetes Mellitus, Type 2
RGD
PMID:18978347 , PMID:22105495 , PMID:18988929 , PMID:16696964
RGD:2307061 , RGD:7364856 , RGD:2307272 , RGD:1598486
NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
G
Il18
interleukin 18
ISO
associated with Diabetes Mellitus, Type 2;protein:increased expression:serum
RGD
PMID:19011009 , PMID:16260350
RGD:4889417 , RGD:8655907
NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
G
Il1a
interleukin 1 alpha
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:decreased tyrosine phosphorylation:vitreous humor
RGD
PMID:18978347
RGD:2307061
NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
G
Il1b
interleukin 1 beta
ISO
associated with Diabetes Mellitus, Type 2; protein:decreased tyrosine phosphorylation:vitreous humor protein:increased expression:serum, vitreous humour
RGD
PMID:18978347 , PMID:16284605
RGD:2307061 , RGD:7401212
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
G
Il6
interleukin 6
susceptibility
ISO
associated with Diabetes Mellitus; DNA:polymorphism:promoter:-174G>C (human) associated with Diabetes Mellitus, Type1;DNA:polymorphism:promoter:-174G>C(human) associated with Diabetes Mellitus, Typpe 1;protein:increased expression:serum: associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)
RGD
PMID:19140096 , PMID:19542902 , PMID:17725274 , PMID:18988929
RGD:2307267 , RGD:7829816 , RGD:7829749 , RGD:2307272
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
G
Ins2
insulin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30463601 , PMID:22046295
RGD:6902909
NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
G
Itga2
integrin subunit alpha 2
severity no_association susceptibility
ISO
associated with Diabetes Mellitus; DNA:transition:cds:807C>T (human) associated with Diabetes Mellitus, Type 2;DNA:snp:cds:c.807T>C (human) associated with Diabetes Mellitus, Type 2;DNA:snp:intron:IVS8-1059T>C (human) associated with Diabetes Mellitus, Type 2;DNA:snp:intron:IVS7+3160A>G (human)
RGD
PMID:12540964 , PMID:21632096 , PMID:18806884 , PMID:23776381
RGD:2307419 , RGD:8686431 , RGD:2313281 , RGD:7777103
NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
G
Itga4
integrin subunit alpha 4
treatment
IMP
associated with Diabetes Mellitus, Experimental
RGD
PMID:19553613
RGD:9698417
NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960
G
Itgb3
integrin subunit beta 3
ISO
protein:increased expression:optic choroid vascular plexus:
RGD
PMID:11375345
RGD:8693344
NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
G
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
treatment
IDA IEP
associated with Diabetes Mellitus, Experimental
RGD
PMID:21672350 , PMID:22143324
RGD:8662869 , RGD:8662907
NCBI chr13:90,722,945...90,753,338
Ensembl chr13:90,723,092...90,752,581
G
Kdm1a
lysine demethylase 1A
IEP ISO
mRNA, protein:increased expression:retina (rat) mRNA:increased expression:retina (human)
RGD
PMID:23423566 , PMID:23423566 , PMID:23423566
RGD:8547881 , RGD:8547881 , RGD:8547881
NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
G
Keap1
Kelch-like ECH-associated protein 1
IEP
associated with Diabetes Mellitus, Experimental;mRNA, protein:increased expression:retina
RGD
PMID:23633659
RGD:10412733
NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
G
Lta
lymphotoxin alpha
no_association susceptibility
ISO
associated with Diabetes Mellitus, Type 2;DNA:polymorphism:intron, exon:252A>G, 804C>A (human)
RGD
PMID:16979413 , PMID:11399938
RGD:8548772 , RGD:8548797
NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
G
Mfn2
mitofusin 2
IEP
associated with Diabetes Mellitus, Experimental;mRNA, protein:decreased expression:retina (rat)
RGD
PMID:28487236
RGD:12910715
NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
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Mir21
microRNA 21
IEP
RNA:increased expression:retina
RGD
PMID:31759996
RGD:41410819
NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
G
Mmp2
matrix metallopeptidase 2
ISO
protein:increased expression:plasma
RGD
PMID:12714657 , PMID:18552985
RGD:1582582 , RGD:8547849
NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
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Mmp9
matrix metallopeptidase 9
disease_progression
ISO
associated with Diabetes Mellitus, Experimental associated with Diabetes Mellitus, Type 2
RGD
PMID:16643893 , PMID:21933988 , PMID:10374894
RGD:1582616 , RGD:8547857 , RGD:8547815
NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
G
Mthfr
methylenetetrahydrofolate reductase
susceptibility
ISO
associated with Diabetes Mellitus, Type 2; DNA:transition:cds:g.677C>T (human)
RGD
PMID:9040583
RGD:6893525
NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
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Mysm1
myb-like, SWIRM and MPN domains 1
susceptibility
ISO
associated with Diabetes Mellitus, Type 2;DNA:snps:introns: IVS1-1269C>T, IVS6+1700G>A (rs2811893, rs12092121) (human)
RGD
PMID:21310492
RGD:9589162
NCBI chr 5:113,902,115...113,939,083
Ensembl chr 5:113,906,803...113,939,127
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Nfe2l2
nuclear factor, erythroid 2-like 2
IDA
associated with Diabetes Mellitus, Experimental;protein:decreased activity:retina
RGD
PMID:23633659
RGD:10412733
NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
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Ngf
nerve growth factor
ISO
protein:increased expression:serum
RGD
PMID:18282491
RGD:7242804
NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
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Nos1
nitric oxide synthase 1
IEP
mRNA, protein:decreased expression:retina
RGD
PMID:17545029
RGD:1642141
NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
G
Nos3
nitric oxide synthase 3
no_association susceptibility treatment severity onset
ISO IDA IEP
associated with Diabetes Mellitus, Type 2;DNA:duplication:intron:IVS4?-?+27 (human) associated with Diabetes Mellitus, Type 2;DNA:snp:exon:c.894G>T (human) associated with Diabetes Mellitus, Type 2;DNA:snps, duplication, haplotype:promoter, cds, intron:g.-786T>C, p.E298N, IVS4?-?+27 (human) associated with Diabetes Mellitus, Experimental associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:retina (rat) DNA:snps:promoter, exon:c.-786T>C, c.774C>T (human) associated with Diabetes Mellitus, Type 1;DNA:duplication:intron:IVS4?-?+27 (human)
RGD
PMID:16581274 , PMID:23776381 , PMID:22017289 , PMID:17558849 , PMID:18840783 , PMID:23059402 , PMID:20435587 , PMID:15890549 , PMID:17973941 , PMID:11918626
RGD:7421531 , RGD:7777103 , RGD:7777101 , RGD:7775042 , RGD:7771606 , RGD:7771569 , RGD:7771568 , RGD:7771565 , RGD:7421533 , RGD:7421532
NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
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Nppa
natriuretic peptide A
ISO
protein:increased expression:vitreous humor
RGD
PMID:15273657
RGD:2313589
NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
G
Npr3
natriuretic peptide receptor 3
IEP
mRNA:decreased expression:retina (rat)
RGD
PMID:15789000
RGD:1580773
NCBI chr 2:61,883,946...61,950,291
Ensembl chr 2:61,888,950...61,949,926
G
Nutf2
nuclear transport factor 2
treatment
ISO IDA
mRNA:decreased expression:peripheral blood:
RGD
PMID:19404486 , PMID:19404486
RGD:9831377 , RGD:9831377
NCBI chr19:37,830,917...37,852,192
Ensembl chr19:37,830,917...37,852,189
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Ocln
occludin
treatment
IEP
RGD
PMID:25685822
RGD:11341734
NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
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Pgf
placental growth factor
IEP
associated with Diabetes Mellitus, Type 2
RGD
PMID:21408222
RGD:6483775
NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
G
Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
IEP
mRNA, protein:increased expression:retina
RGD
PMID:31759996
RGD:41410819
NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
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Pon1
paraoxonase 1
susceptibility
ISO
DNA:polymorphism:promoter:g.-907C>G (human) CTD Direct Evidence: marker/mechanism associated with Diabetes Mellitus;DNA:missense mutation:cds:p.L55M (rs854560) (human) associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.Q192R (human) associated with Diabetes Mellitus, Type 1;protein:decreased activity:serum (human)
CTD
PMID:9661650 PMID:20012460 , PMID:16949520 , PMID:24100645 , PMID:15270786 , PMID:20012460
RGD:2313272 , RGD:8547572 , RGD:8547548 , RGD:8547537
NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
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Pparg
peroxisome proliferator-activated receptor gamma
ISO
Retinal Leukostasis;associated with Diabetes Mellitus, Experimental
RGD
PMID:17003451
RGD:8552824
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
G
Ppargc1a
PPARG coactivator 1 alpha
IDA IEP
associated with Diabetes Mellitus, Experimental; mRNA:increased expression:retina (rat)
RGD
PMID:20566666 , PMID:22003111
RGD:6484532 , RGD:5686899
NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
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Pten
phosphatase and tensin homolog
IEP
mRNA, protein:decreased expression:retina
RGD
PMID:31759996
RGD:41410819
NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
G
Retn
resistin
ISO
associated with Diabetes Mellitus, Type 2
RGD
PMID:17303077
RGD:7207162
NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
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RT1-Bb
RT1 class II, locus Bb
susceptibility severity
ISO
associated with Diabetes Mellitus, Type 1;DNA:polymorphisms, haplotypes:cds:HLA-DQB1*0201, HLA-DQB1*0501, HLA-DQB1*0504 (human) DNA:polymorphisms, haplotype:cds:HLA-DQB1*0201, HLA-DQB1*0302 (human)
RGD
PMID:19551681 , PMID:8932997
RGD:7421552 , RGD:7483573
NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
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RT1-CE13
RT1 class I, locus CE13
susceptibility
ISO
associated with Diabetes Mellitus, Type 1; DNA:polymorphisms:cds:HLA-B*49 (human)
RGD
PMID:22981956
RGD:7365095
G
RT1-Db1
RT1 class II, locus Db1
susceptibility
ISO
associated with Diabetes Mellitus Type 1;DNA:polymorphism::DRB1*0301,DRB1*0402(human)
RGD
PMID:23837223
RGD:7365113
NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
G
Serpina4
serpin family A member 4
ISO
protein:decreased expression:vitreous fluid (human)
RGD
PMID:8950506
RGD:1580289
NCBI chr 6:127,743,883...127,753,047
Ensembl chr 6:127,743,971...127,753,046
G
Serpine1
serpin family E member 1
susceptibility no_association
ISO
associated with Diabetes Mellitus, Type 2;DNA:deletion:promoter:g.-676_-674delG (human) associated with Diabetes Mellitus, Type 2;DNA:snp, deletion:promoter:g.-844G>A, g.-676_-674delG (human) associated with Diabetes Mellitus;repeat, snp:intron, 3' utr:g.7844(CA)1-6, ? (human) associated with Diabetes Mellitus, Type 1;protein:increased expression:plasma (human)
RGD
PMID:23281898 , PMID:19419896 , PMID:7974340 , PMID:9201602 , PMID:12660488
RGD:8547697 , RGD:8547741 , RGD:8547740 , RGD:8547710 , RGD:8547699
NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
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Serpinf1
serpin family F member 1
severity
ISO IEP
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNPs:promoter:g.-5740T>C, g.-5308G>A (rs12150053, rs12948385) (human) protein:alternative form:vitreous humor associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:serum associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:retina associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:vitreous humor
RGD
PMID:17658465 , PMID:19365032 , PMID:18455830 , PMID:16054135 , PMID:18025835 , PMID:15059706
RGD:2312346 , RGD:2312337 , RGD:2312341 , RGD:2312348 , RGD:2312344 , RGD:1580135
NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
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Sgf29
SAGA complex associated factor 29
severity
ISO
associated with Diabetes Mellitus, Type 1; DNA:SNP:intron: rs10521145(human)
RGD
PMID:21441570
RGD:9587455
NCBI chr 1:198,066,974...198,100,494
Ensembl chr 1:198,067,066...198,100,493
G
Sirt1
sirtuin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24894401
NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
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Sod1
superoxide dismutase 1
ISO
human gene in a mouse model CTD Direct Evidence: therapeutic
CTD
PMID:19074809 , PMID:19074809
RGD:8655572
NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
G
Sod3
superoxide dismutase 3
ISO
RGD
PMID:12663605
RGD:1581298
NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
G
Thbs1
thrombospondin 1
IEP ISO
associated with Diabetes Mellitus, Experimental CTD Direct Evidence: marker/mechanism
CTD
PMID:17117553 , PMID:17117553
RGD:2317943
NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
G
Timm44
translocase of inner mitochondrial membrane 44
IEP
associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:retina
RGD
PMID:22003103
RGD:13463597
NCBI chr12:2,517,006...2,533,707
Ensembl chr12:2,517,006...2,533,706
G
Tlr4
toll-like receptor 4
onset
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.N299G (human)
RGD
PMID:19135114
RGD:2312487
NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
G
Tnf
tumor necrosis factor
no_association disease_progression
ISO
associated with Diabetes Mellitus, Type 2 associated with Diabetes Mellitus, Type 2;DNA:polymorphism:promoter:-302A>G (human) protein:increased expression:serum, vitreous humour associated with Diabetes Mellitus, Type 1;protein:increased expression:platelet:
RGD
PMID:22105495 , PMID:16979413 , PMID:16284605 , PMID:10540181
RGD:7364856 , RGD:8548772 , RGD:7401212 , RGD:7394805
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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Uts2
urotensin 2
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma
RGD
PMID:18338983
RGD:2306795
NCBI chr 5:168,078,748...168,084,133
Ensembl chr 5:168,078,748...168,084,145
G
Vcam1
vascular cell adhesion molecule 1
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:vitreous humor, serum
RGD
PMID:19237221
RGD:2312762
NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
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Vdr
vitamin D receptor
ISO
RGD
PMID:15899948
RGD:1580363
NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
G
Vegfa
vascular endothelial growth factor A
ISO IEP
mRNA, protein:increased expression:retina CTD Direct Evidence: marker/mechanism associated with Diabetes Mellitus, type 2; protein:increased expression:aqueous humor of eyeball:
CTD
PMID:11978667 PMID:15788408 PMID:20577866 , PMID:17513698 , PMID:31759996 , PMID:9852717 , PMID:16636650
RGD:2301992 , RGD:41410819 , RGD:8547996 , RGD:1580565
NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
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Vtn
vitronectin
ISO IEP
associated with Diabetes Mellitus, Experimental
RGD
PMID:7536680 , PMID:8804356
RGD:1580818 , RGD:10040982
NCBI chr10:65,767,960...65,771,040
Ensembl chr10:65,767,053...65,771,038
G
Vwf
von Willebrand factor
ISO
RGD
PMID:10077454
RGD:1580648
NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
G
A2m
alpha-2-macroglobulin
treatment
ISO
RGD
PMID:10848441
RGD:10046010
NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
G
Cat
catalase
ISO
associated withDiabetes Mellitus, Type 2; mRNA,protein:decreased expression, decreased activity:blood,l serum:
RGD
PMID:24092995
RGD:9068931
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
G
Flt1
Fms related receptor tyrosine kinase 1
ISO
protein:decreased expression:aqueous humor:
RGD
PMID:23853629
RGD:10402120
NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
G
Pdgfb
platelet derived growth factor subunit B
ISO
protein:decreased expression:vitreous:
RGD
PMID:19799585
RGD:10449447
NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
G
Lrrc32
leucine rich repeat containing 32
ISO
ClinVar Annotator: match by term: CLEFT PALATE, PROLIFERATIVE RETINOPATHY, AND DEVELOPMENTAL DELAY
ClinVar OMIM
PMID:30976112
NCBI chr 1:163,443,972...163,457,426
Ensembl chr 1:163,445,527...163,457,424
G
Adipoq
adiponectin, C1Q and collagen domain containing
ISO
associated with Diabetes Mellitus, Type 2;protein:increased expression:aqueous humor
RGD
PMID:22563689
RGD:8694466
NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
G
Ager
advanced glycosylation end product-specific receptor
ISO
protein:increased expression:vitreous humor
RGD
PMID:16364297
RGD:8695978
NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
G
Cat
catalase
ISO
associated withDiabetes Mellitus, Type 2; mRNA,protein:decreased expression, decreased activity:blood,l serum:
RGD
PMID:24092995
RGD:9068931
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
G
Ccl2
C-C motif chemokine ligand 2
disease_progression
ISO
associated with Diabetes Mellitus, Type 2;DNA:polymorphism:promoter:g.-2518A>G (human) associated with Diabetes Mellitus;protein:increased expression:vitreous humor (human)
RGD
PMID:23549806 , PMID:21850157
RGD:8548851 , RGD:8549477
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
G
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
disease_progression
ISO
protein:decreased expression:vitreous:
RGD
PMID:22864860
RGD:9685437
NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
G
Flt1
Fms related receptor tyrosine kinase 1
ISO
protein:increased expression:vitreous:
RGD
PMID:22868384
RGD:10402118
NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
G
Il6r
interleukin 6 receptor
ISO
protein:increased expression:serum
RGD
PMID:17401618
RGD:10402814
NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
G
Pdgfb
platelet derived growth factor subunit B
ISO
protein:increased expression:vitreous:
RGD
PMID:19799585
RGD:10449447
NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
G
Pparg
peroxisome proliferator-activated receptor gamma
onset susceptibility
ISO
associated with Diabetes Mellitus, Type 2;DNA:snp:promoter:c.-2819A>G (human) DNA:snp:cds:p.P12A (rs1801282) (human)
RGD
PMID:18541841 , PMID:19125195 , PMID:23559865
RGD:2301854 , RGD:8699508 , RGD:8552820
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
G
Serpine1
serpin family E member 1
susceptibility disease_progression
ISO
associated with Diabetes Mellitus, Type 2;DNA:deletion:promoter:g.-676_-674delG (human) protein:increased expression:plasma (human)
RGD
PMID:16416371 , PMID:23304115
RGD:8699494 , RGD:8699497
NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
G
Serpinf1
serpin family F member 1
treatment
ISO
protein:increased expression:vitreous fluid (human)
RGD
PMID:11723044 , PMID:15059706
RGD:8554895 , RGD:1580135
NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
G
Srsf6
serine and arginine rich splicing factor 6
ISO
DNA:snp:exon:p.P281P (rs2235611) (human)
RGD
PMID:21309690
RGD:11039452
NCBI chr 3:159,305,345...159,310,668
Ensembl chr 3:159,305,345...159,310,668
G
Timm44
translocase of inner mitochondrial membrane 44
ISO
mRNA:decreased expression:retina
RGD
PMID:22003103
RGD:13463597
NCBI chr12:2,517,006...2,533,707
Ensembl chr12:2,517,006...2,533,706
G
Vegfa
vascular endothelial growth factor A
IDA
associated with Diabetes Mellitus, Type 2; protein:increased expression:retina
RGD
PMID:16054135
RGD:2312348
NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
G
Pdgfrb
platelet derived growth factor receptor beta
ISS
MouseDO
NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
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