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GENE - TERM ANNOTATION REPORT

2 Annotations Found.

An association has been curated linking Adam17 and Alzheimer's disease in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Wang L, etal., Neurochem Res. 2014 Jul;39(7):1338-45. doi: 10.1007/s11064-014-1317-z. Epub 2014 May 3.
  • The annotation has been inferred from sequence orthology with Adam17 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 8 additional annotations were made from Wang L, etal., Neurochem Res. 2014 Jul;39(7):1338-45. doi: 10.1007/s11064-014-1317-z. Epub 2014 May 3.
  • 497 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 29 papers in RGD have been used to annotate Adam17
  • Curation Notes: protein:decreased expression:cerebral cortex, hippocampus


    • An association has been curated linking Adam17 and Alzheimer's disease in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Hartl D, etal., Mol Psychiatry. 2018 Jul 9. pii: 10.1038/s41380-018-0091-8. doi: 10.1038/s41380-018-0091-8.
  • The annotation has been inferred from sequence orthology with ADAM17 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Hartl D, etal., Mol Psychiatry. 2018 Jul 9. pii: 10.1038/s41380-018-0091-8. doi: 10.1038/s41380-018-0091-8.
  • 497 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 29 papers in RGD have been used to annotate Adam17
  • Qualifier: onset
  • Curation Notes: DNA:missense mutation: :p.R215I (rs142946965) (human)


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