Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - TERM ANNOTATION REPORT

13 Annotations Found.

An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with CREB1 (Homo sapiens) [(EXP) inferred from experiment]
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:18596687


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Pandey SC, etal., J Neurochem. 2001 May;77(3):943-52. doi: 10.1046/j.1471-4159.2001.00309.x.
  • The annotation has been inferred from sequence orthology with Creb1 (Rattus norvegicus) [(IDA) inferred from direct assay]
  • 2 additional annotations were made from Pandey SC, etal., J Neurochem. 2001 May;77(3):943-52. doi: 10.1046/j.1471-4159.2001.00309.x.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Curation Notes: associated with nicotine dependence;protein:decreased expression, decreased phosphorylation:brain, multiple


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from direct assay (IDA)
  •  
  • The annotation was made from Liu WT, etal., FASEB J. 2009 Jan;23(1):90-8. doi: 10.1096/fj.08-114462. Epub 2008 Sep 4.
  • 17 additional annotations were made from Liu WT, etal., FASEB J. 2009 Jan;23(1):90-8. doi: 10.1096/fj.08-114462. Epub 2008 Sep 4.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Qualifier: treatment
  • Curation Notes: associated with morphine dependence


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Peregud DI, etal., Neurochem Res. 2015 Jan;40(1):130-8. doi: 10.1007/s11064-014-1476-y. Epub 2014 Nov 13.
  • The annotation has been inferred from sequence orthology with Creb1 (Rattus norvegicus) [(IDA) inferred from direct assay]
  • 5 additional annotations were made from Peregud DI, etal., Neurochem Res. 2015 Jan;40(1):130-8. doi: 10.1007/s11064-014-1476-y. Epub 2014 Nov 13.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Curation Notes: associated with morphine dependence;protein:increased promoter binding:frontal cortex, midbrain


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from direct assay (IDA)
  •  
  • The annotation was made from Dominguez G, etal., Cogn Affect Behav Neurosci. 2018 Aug;18(4):665-679. doi: 10.3758/s13415-018-0595-3.
  • 2 additional annotations were made from Dominguez G, etal., Cogn Affect Behav Neurosci. 2018 Aug;18(4):665-679. doi: 10.3758/s13415-018-0595-3.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Qualifier: treatment
  • Curation Notes: associated with alcohol dependence


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Wang WS, etal., J Neurosci. 2012 Oct 3;32(40):13763-75. doi: 10.1523/JNEUROSCI.1991-12.2012.
  • The annotation has been inferred from sequence orthology with Creb1 (Rattus norvegicus) [(IDA) inferred from direct assay]
  • 8 additional annotations were made from Wang WS, etal., J Neurosci. 2012 Oct 3;32(40):13763-75. doi: 10.1523/JNEUROSCI.1991-12.2012.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Curation Notes: associated with morphine dependence;protein:increased phosphorylation:prefrontal cortex


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Han MH, etal., J Neurosci. 2006 Apr 26;26(17):4624-9. doi: 10.1523/JNEUROSCI.4701-05.2006.
  • The annotation has been inferred from sequence orthology with Creb1 (Rattus norvegicus) [(IMP) inferred from mutant phenotype]
  • 3 additional annotations were made from Han MH, etal., J Neurosci. 2006 Apr 26;26(17):4624-9. doi: 10.1523/JNEUROSCI.4701-05.2006.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Curation Notes: associated with morphine dependence


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Dulman RS, etal., Alcohol Clin Exp Res. 2021 Oct;45(10):2006-2016. doi: 10.1111/acer.14691. Epub 2021 Aug 28.
  • The annotation has been inferred from sequence orthology with Creb1 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Dulman RS, etal., Alcohol Clin Exp Res. 2021 Oct;45(10):2006-2016. doi: 10.1111/acer.14691. Epub 2021 Aug 28.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Curation Notes: associated with alcohol use disorder;mRNA:increased expression:cerebellum


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Bobzean SAM, etal., Neurosci Lett. 2019 Jul 13;705:124-130. doi: 10.1016/j.neulet.2019.04.057. Epub 2019 Apr 28.
  • The annotation has been inferred from sequence orthology with Creb1 (Rattus norvegicus) [(IDA) inferred from direct assay]
  • 2 additional annotations were made from Bobzean SAM, etal., Neurosci Lett. 2019 Jul 13;705:124-130. doi: 10.1016/j.neulet.2019.04.057. Epub 2019 Apr 28.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Qualifier: sexual_dimorphism
  • Curation Notes: associated with morphine dependence;protein:altered phosphorylation:ventral tegmental area


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Sun A, etal., Neurosci Lett. 2015 Mar 30;591:166-170. doi: 10.1016/j.neulet.2015.02.048. Epub 2015 Feb 21.
  • The annotation has been inferred from sequence orthology with Creb1 (Rattus norvegicus) [(IDA) inferred from direct assay]
  • 8 additional annotations were made from Sun A, etal., Neurosci Lett. 2015 Mar 30;591:166-170. doi: 10.1016/j.neulet.2015.02.048. Epub 2015 Feb 21.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Curation Notes: associated with heroin dependence;protein:decreased phosphorylation:nucleus accumbens


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Pandey SC, etal., J Pharmacol Exp Ther. 2001 Mar;296(3):857-68.
  • The annotation has been inferred from sequence orthology with Creb1 (Rattus norvegicus) [(IDA) inferred from direct assay]
  • 8 additional annotations were made from Pandey SC, etal., J Pharmacol Exp Ther. 2001 Mar;296(3):857-68.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Curation Notes: associated with alcohol use disorder;protein:altered phosphorylation:brain, nucleus


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from direct assay (IDA)
  •  
  • The annotation was made from Roni MA and Rahman S, Psychopharmacology (Berl). 2014 Aug;231(15):2989-98. doi: 10.1007/s00213-014-3472-y. Epub 2014 Feb 28.
  • 5 additional annotations were made from Roni MA and Rahman S, Psychopharmacology (Berl). 2014 Aug;231(15):2989-98. doi: 10.1007/s00213-014-3472-y. Epub 2014 Feb 28.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Qualifier: treatment
  • Curation Notes: associated with nicotine dependence


  • An association has been curated linking Creb1 and withdrawal disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Zhang L, etal., Neurol Res. 2009 Sep;31(7):738-42. doi: 10.1179/174313209X382386. Epub 2008 Dec 23.
  • The annotation has been inferred from sequence orthology with Creb1 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Zhang L, etal., Neurol Res. 2009 Sep;31(7):738-42. doi: 10.1179/174313209X382386. Epub 2008 Dec 23.
  • 104 RGD objects have been annotated to withdrawal disorder  (DOID:0060001)
  • 101 papers in RGD have been used to annotate Creb1
  • Curation Notes: associated with morphine dependence


  • Go Back to source page   Continue to Ontology report