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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
3'-flap endonuclease activity  
5'-flap endonuclease activity  
Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis.
CC-preferring endodeoxyribonuclease activity 
class II DNA-(apurinic or apyrimidinic site) endonuclease activity  
deoxyribonuclease I activity  
deoxyribonuclease IV (phage-T4-induced) activity 
deoxyribonuclease V activity 
type I site-specific deoxyribonuclease activity 
type II site-specific deoxyribonuclease activity 
type III site-specific deoxyribonuclease activity 

Synonyms
Xrefs: Reactome:R-HSA-174441 "Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand" ;   reactome:R-HSA-110363 "FEN1 bound to PCNA and APEX1 cleaves flap ssDNA" ;   reactome:R-HSA-174446 "Removal of remaining Flap from the C-strand" ;   reactome:R-HSA-5651782 "FEN1 bound to POLB cleaves displaced DNA strand (flap)" ;   reactome:R-HSA-5687664 "FEN1 cleaves displaced ssDNA flaps during MMEJ" ;   reactome:R-HSA-69152 "Removal of remaining Flap"
Definition Sources: PMID:9778254

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