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CROSS-SPECIES ANATOMY - ANNOTATIONS

The Basic subset of the UBERON integrated, cross-species anatomy ontology is downloaded weekly from http://berkeleybop.org/ontologies/uberon/basic.obo. For more information about this ontology see the "About" page on the UBERON website at http://uberon.github.io/about.html.
Term:pharyngeal pouch
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Accession:UBERON:0004117 term browser browse the term
Definition:An internal pocketing of pharyngeal endoderm that contacts a region of ectoderm (a pharyngeal cleft) and interdigitates in the anterior and posterior directions with the pharyngeal arches.
Comment:The pouches are polarized structures. For example, whereas the rostral half of each pouch expresses Bmp-7, the caudal half expresses FGF-8 and the dorsal aspect of each pouch is marked via its expression of Pax-1. each pouch has an individual sense of identity. Shh expression is a prominent early feature of the caudal endoderm of the second arch, and individual pouches mark the anterior limits of expression of Hox genes within the pharyngeal endoderm; Hox-a2 has a rostral boundary at the second pouch, Hox-a3 at the third pouch and Hox-a4 at the most caudal pouch[PMID:16313389]; [homology-note] "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001203", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M, Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"}
Synonyms:exact_synonym: branchial pouch;   visceral pouch
 related_synonym: pharyngeal pouches;   visceral pouches
 xref: AAO:0011113;   EFO:0003627;   EHDAA:1086;   EHDAA:1669;   EHDAA:579;   EHDAA:617;   EMAPA:32752;   FMA:293063;   NCI:C34252;   SCTID:34674002;   TAO:0001106;   UMLS:C0231067;   VHOG:0001203;   Wikipedia:Pharyngeal_pouch_(embryology);   XAO:0000282;   ZFA:0001106


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Term paths to the root
Path 1
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        developing anatomical structure 0
          embryonic structure 0
            pharyngeal pouch 0
              parathyroid epithelium + 0
              pharyngeal gill precursor + 0
              pharyngeal pouch 1 + 0
              pharyngeal pouch 2 + 0
              pharyngeal pouch 3 + 0
              pharyngeal pouch 4 + 0
              pharyngeal pouch 5 + 0
              pharyngeal pouch 6 0
              pharyngeal pouches 2-6 0
              ultimobranchial body + 0
Path 2
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          multicellular anatomical structure 0
            multicellular organism 0
              embryo 0
                embryonic structure 0
                  presumptive structure 0
                    presumptive gut 0
                      digestive tract 0
                        subdivision of digestive tract 0
                          foregut 0
                            pharyngeal region of foregut 0
                              pharyngeal arch system 0
                                entire pharyngeal arch endoderm 0
                                  early pharyngeal endoderm 0
                                    pharyngeal pouch 0
                                      parathyroid epithelium + 0
                                      pharyngeal gill precursor + 0
                                      pharyngeal pouch 1 + 0
                                      pharyngeal pouch 2 + 0
                                      pharyngeal pouch 3 + 0
                                      pharyngeal pouch 4 + 0
                                      pharyngeal pouch 5 + 0
                                      pharyngeal pouch 6 0
                                      pharyngeal pouches 2-6 0
                                      ultimobranchial body + 0
paths to the root