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CROSS-SPECIES ANATOMY - ANNOTATIONS

The Basic subset of the UBERON integrated, cross-species anatomy ontology is downloaded weekly from http://berkeleybop.org/ontologies/uberon/basic.obo. For more information about this ontology see the "About" page on the UBERON website at http://uberon.github.io/about.html.
Term:heart
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Accession:UBERON:0000948 term browser browse the term
Definition:A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ.
Comment:Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706; [homology-note] "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000276", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.481", source="http://bgee.unil.ch/"}
Synonyms:exact_synonym: chambered heart;   vertebrate heart
 narrow_synonym: branchial heart
 related_synonym: cardium
 xref: AAO:0010210;   BILA:0000020;   BTO:0000562;   CALOHA:TS-0445;   EFO:0000815;   EHDAA2:0000738;   EHDAA:420;   EMAPA:16105;   EV:0100018;   FMA:7088;   GAID:174;   MA:0000072;   MAT:0000036;   MESH:D006321;   MIAA:0000036;   NCI:C12727;   SCTID:302509004;   TAO:0000114;   UMLS:C0018787;   VHOG:0000276;   Wikipedia:Heart;   XAO:0000064;   ZFA:0000114;   galen:Heart
 relational_adjective: cardiac
 external_ontology: never_in_taxon NCBITaxon:6239;   never_in_taxon NCBITaxon:7227;   present_in_taxon NCBITaxon:9606
 axiom_lost: relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010210", ontology="AAO)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010210", ontology="AAO


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Term paths to the root
Path 1
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          mesoderm-derived structure 0
            heart 0
              apex of heart 0
              atrioventricular region + 0
              basal zone of heart 0
              bulbo-ventricular groove 0
              bulbus cordis + 0
              cardiac chamber + 0
              cardiac jelly + 0
              cardiac mesenchyme + 0
              cardiac septum + 0
              cardiac skeleton 0
              cardiac valve + 0
              coronary vessel + 0
              epicardium + 0
              fibrous ring of heart + 0
              foramen of Panizza 0
              heart elastic tissue 0
              heart endothelium + 0
              heart layer + 0
              heart vasculature + 0
              inflow tract + 0
              interventricular foramen of heart 0
              mesentery of heart + 0
              outflow tract + 0
              wall of heart + 0
Path 2
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          multicellular anatomical structure 0
            multicellular organism 0
              embryo 0
                embryonic structure 0
                  epiblast (generic) 0
                    germ layer / neural crest 0
                      germ layer 0
                        mesoderm 0
                          mesoderm-derived structure 0
                            lateral plate mesoderm 0
                              primary heart field 0
                                cardiogenic splanchnic mesoderm 0
                                  heart primordium 0
                                    cardiogenic plate 0
                                      heart rudiment 0
                                        primitive heart tube 0
                                          heart tube 0
                                            heart 0
                                              apex of heart 0
                                              atrioventricular region + 0
                                              basal zone of heart 0
                                              bulbo-ventricular groove 0
                                              bulbus cordis + 0
                                              cardiac chamber + 0
                                              cardiac jelly + 0
                                              cardiac mesenchyme + 0
                                              cardiac septum + 0
                                              cardiac skeleton 0
                                              cardiac valve + 0
                                              coronary vessel + 0
                                              epicardium + 0
                                              fibrous ring of heart + 0
                                              foramen of Panizza 0
                                              heart elastic tissue 0
                                              heart endothelium + 0
                                              heart layer + 0
                                              heart vasculature + 0
                                              inflow tract + 0
                                              interventricular foramen of heart 0
                                              mesentery of heart + 0
                                              outflow tract + 0
                                              wall of heart + 0
paths to the root