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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased malignant tumor incidence
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Accession:MP:0002018 term browser browse the term
Definition:higher than normal incidence of locally invasive, destructive and metastatic tumors
Synonyms:exact_synonym: increased malignant tumour incidence
 related_synonym: malignant tumors;   malignant tumours


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increased intestinal adenocarcinoma incidence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway sexual_dimorphism IMP compared to treated females RGD PMID:17360473 RGD:1601201 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G ApcPirc APC, WNT signaling pathway regulator; polyposis in the rat colon sexual_dimorphism IMP compared to treated females RGD PMID:17360473 RGD:1601201
increased osteosarcoma incidence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 IAGP DNA:deletion RGD PMID:19825367 RGD:5147850 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    neoplasm 244
      abnormal tumor susceptibility 236
        abnormal tumor incidence 225
          abnormal classified tumor incidence 105
            increased classified tumor incidence 105
              increased malignant tumor incidence 64
                increased blastoma incidence + 0
                increased carcinoma incidence + 61
                increased malignant triton tumor incidence 0
                increased melanoma incidence + 0
                increased sarcoma incidence + 3
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