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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased osteosarcoma incidence
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Accession:MP:0003789 term browser browse the term
Definition:greater than the expected number of a malignant neoplasm derived form mesenchymal stem cells, osteoblasts or osteocytes, occurring in a specific population in a given time period; osteosarcoma is a highly invasive and destructive tumor rising in the skeleton with osteoid and immature woven bone
Synonyms:related_synonym: osteogenic sarcoma



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increased osteosarcoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 IAGP DNA:deletion RGD PMID:19825367 RGD:5147850 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
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Path 1
Term Annotations click to browse term
  mammalian phenotype 5368
    skeleton phenotype 431
      abnormal skeleton morphology 336
        increased skeletal tumor incidence 1
          increased osteosarcoma incidence 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 5368
    neoplasm 243
      abnormal tumor susceptibility 236
        abnormal tumor incidence 225
          increased tumor incidence 166
            increased classified tumor incidence 105
              increased malignant tumor incidence 64
                increased sarcoma incidence 3
                  increased osteosarcoma incidence 1
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