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ONTOLOGY REPORT - ANNOTATIONS

Term:histone H4K20 monomethyltransferase activity
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Accession:GO:0140944 term browser browse the term
Definition:Catalysis of the reaction: L-lysyl20-[histone H4] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl20-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the unmethylated lysine residue at position 20 of histone H4, producing histone H4K20me.
Synonyms:exact_synonym: histone H4K20 monomethylation;   histone lysine N-monomethyltransferase activity (H4-K20 specific)
 broad_synonym: histone H4-K20 methylation;   histone H4K20 methylase activity;   histone H4K20 methylation
 xref: EC:2.1.1.361;   RHEA:60344


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histone H4K20 monomethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07010705.1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 Ensembl chr 2:142,289,467...142,290,623 JBrowse link
G AABR07033047.1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 Ensembl chr11:3,479,411...3,480,543 JBrowse link
G Kmt5a lysine methyltransferase 5A enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711 		JBrowse link
G Kmt5al2 lysine methyltransferase 5A like 2 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr  X:92,178,344...92,180,517
Ensembl chr  X:92,178,016...92,179,731 		JBrowse link
G Kmt5b lysine methyltransferase 5B enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819 		JBrowse link
G Kmt5c lysine methyltransferase 5C enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145 		JBrowse link
G Prdm9 PR/SET domain 9 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:56,505,579...56,525,726
Ensembl chr 1:56,505,579...56,525,652 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20486
    catalytic activity 6038
      catalytic activity, acting on a protein 2445
        protein methyltransferase activity 106
          protein-lysine N-methyltransferase activity 67
            histone H4K20 methyltransferase activity 12
              histone H4K20 monomethyltransferase activity 7
Path 2
Term Annotations click to browse term
  molecular_function 20486
    catalytic activity 6038
      transferase activity 2398
        transferase activity, transferring one-carbon groups 218
          methyltransferase activity 208
            S-adenosylmethionine-dependent methyltransferase activity 168
              lysine N-methyltransferase activity 67
                protein-lysine N-methyltransferase activity 67
                  histone H4K20 methyltransferase activity 12
                    histone H4K20 monomethyltransferase activity 7
paths to the root