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ONTOLOGY REPORT - ANNOTATIONS

Term:high-affinity sodium:dicarboxylate symporter activity
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Accession:GO:0015362 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
Synonyms:broad_synonym: high affinity sodium:dicarboxylate cotransporter activity
 xref: reactome:R-HSA-433101 "NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion"


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high-affinity sodium:dicarboxylate symporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc13a3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 enables IDA (PMID:11287335) MGI PMID:11287335 NCBI chr 2:165,247,215...165,315,117
Ensembl chr 2:165,246,948...165,315,150 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28831
    transporter activity 1198
      transmembrane transporter activity 1108
        organic acid transmembrane transporter activity 200
          organic acid:sodium symporter activity 36
            sodium:dicarboxylate symporter activity 3
              high-affinity sodium:dicarboxylate symporter activity 1
Path 2
Term Annotations click to browse term
  molecular_function 28831
    transporter activity 1198
      transmembrane transporter activity 1108
        inorganic molecular entity transmembrane transporter activity 684
          inorganic cation transmembrane transporter activity 562
            metal ion transmembrane transporter activity 444
              sodium ion transmembrane transporter activity 160
                solute:sodium symporter activity 81
                  organic acid:sodium symporter activity 36
                    sodium:dicarboxylate symporter activity 3
                      high-affinity sodium:dicarboxylate symporter activity 1
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