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ONTOLOGY REPORT - ANNOTATIONS

Term:fibroblast growth factor receptor activity
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Accession:GO:0005007 term browser browse the term
Definition:Combining with a fibroblast growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Comment:Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand FGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
Synonyms:exact_synonym: FGF receptor activity;   FGF-activated receptor activity;   FGFR;   fibroblast growth factor-activated receptor activity


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fibroblast growth factor receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR1 fibroblast growth factor receptor 1 enables IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:15282342 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:6480435 NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:15231666 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1304345 NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 enables IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:172,386,443...172,400,271
Ensembl chr 5:179,454,995...179,467,605 		JBrowse link
G FGFRL1 fibroblast growth factor receptor like 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:1,125,623...1,142,884
Ensembl chr 4:1,045,583...1,059,936 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17492
    catalytic activity 5384
      catalytic activity, acting on a protein 2227
        protein kinase activity 558
          transmembrane receptor protein kinase activity 75
            transmembrane receptor protein tyrosine kinase activity 58
              fibroblast growth factor receptor activity 5
Path 2
Term Annotations click to browse term
  molecular_function 17492
    catalytic activity 5384
      transferase activity 2182
        transferase activity, transferring phosphorus-containing groups 854
          kinase activity 716
            protein kinase activity 558
              protein tyrosine kinase activity 119
                transmembrane receptor protein tyrosine kinase activity 58
                  fibroblast growth factor receptor activity 5
paths to the root