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ONTOLOGY REPORT - ANNOTATIONS

Term:glucose-6-phosphatase activity
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Accession:GO:0004346 term browser browse the term
Definition:Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.
Synonyms:related_synonym: D-glucose-6-phosphate phosphohydrolase activity;   glucose 6-phosphate phosphatase activity
 xref: EC:3.1.3.9;   KEGG_REACTION:R00303;   MetaCyc:RXN66-526;   RHEA:16689;   Reactome:R-HSA-3262512 "G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous)";   Reactome:R-HSA-3266566 "G6PC2 hydrolyzes G6P to form Glc and Pi (islet)";   Reactome:R-HSA-3274540 "Defective G6PC does not hydrolyze glucose 6-phosphate";   Reactome:R-HSA-3282876 "Defective G6PC3 does not hydrolyze glucose 6-phosphate";   Reactome:R-HSA-71825 "G6PC hydrolyzes G6P to Glc and Pi (liver)"

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glucose-6-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pc1 glucose-6-phosphatase catalytic subunit 1 enables IEA
ISO		 InterPro
Ensembl
UniProt
RGD
RHEA
TreeGrafter		 PMID:4303362 PMID:4353083 PMID:11440903 PMID:12757934 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117 GO_REF:0000118 RGD:1601265 RGD:2302850 RGD:2302851 RGD:2302970 NCBI chrNW_004936490:17,605,865...17,614,754
Ensembl chrNW_004936490:17,605,865...17,615,145 		JBrowse link
G G6pc2 glucose-6-phosphatase catalytic subunit 2 enables IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936469:10,612,394...10,618,542
Ensembl chrNW_004936469:10,612,394...10,618,542 		JBrowse link
G G6pc3 glucose-6-phosphatase catalytic subunit 3 enables ISO
IEA		 RGD
TreeGrafter
UniProt
Ensembl
InterPro		 PMID:4303362 PMID:4353083 PMID:11440903 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 RGD:2302850 RGD:2302851 RGD:2302970 NCBI chrNW_004936541:556,413...561,336
Ensembl chrNW_004936541:556,307...561,333 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 17094
    catalytic activity 5319
      hydrolase activity 2262
        hydrolase activity, acting on ester bonds 745
          phosphoric ester hydrolase activity 364
            phosphatase activity 277
              carbohydrate phosphatase activity 11
                sugar-phosphatase activity 10
                  sugar-terminal-phosphatase activity 3
                    glucose-6-phosphatase activity 3
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