Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:glucose-6-phosphatase activity
go back to main search page
Accession:GO:0004346 term browser browse the term
Definition:Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.
Synonyms:related_synonym: D-glucose-6-phosphate phosphohydrolase activity;   glucose 6-phosphate phosphatase activity
 xref: EC:3.1.3.9;   KEGG_REACTION:R00303;   MetaCyc:RXN66-526;   RHEA:16689;   Reactome:R-HSA-3262512 "G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous)";   Reactome:R-HSA-3266566 "G6PC2 hydrolyzes G6P to form Glc and Pi (islet)";   Reactome:R-HSA-3274540 "Defective G6PC does not hydrolyze glucose 6-phosphate";   Reactome:R-HSA-3282876 "Defective G6PC3 does not hydrolyze glucose 6-phosphate";   Reactome:R-HSA-71825 "G6PC hydrolyzes G6P to Glc and Pi (liver)"


show annotations for term's descendants           Sort by:
glucose-6-phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pc1 glucose-6-phosphatase catalytic subunit 1 enables TAS
ISO
IBA
IEA
IDA		 MGI:2387343 (PMID:10625614), (PMID:10787428), (PMID:11121425), (PMID:15087461), (PMID:29428299), (PMID:8407995), (PMID:8640227)
GO_REF:0000033
GO_REF:0000117
(PMID:10318794), (PMID:12093795), (PMID:15661744), (PMID:8211187)		 RGD
GO_Central
UniProt		 PMID:8211187 PMID:8407995 PMID:8640227 PMID:10318794 PMID:10625614 More... GO_REF:0000033 GO_REF:0000117, RGD:728661, RGD:2302970, RGD:2302851, RGD:1601265, RGD:2302850 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G G6pc2 glucose-6-phosphatase catalytic subunit 2 enables ISO (PMID:14722102)
MGI:3819785 (PMID:14722102), (PMID:23274894)		 RGD PMID:14722102 PMID:23274894 NCBI chr 3:53,999,821...54,005,539 JBrowse link
G G6pc3 glucose 6 phosphatase catalytic subunit 3 enables IDA
ISO
IEA
IBA		 (PMID:14718531), (PMID:25492228)
GO_REF:0000117
GO_REF:0000033
(PMID:15661744)		 RGD
UniProt
GO_Central		 PMID:14718531 PMID:15661744 PMID:25492228 PMID:4303362 PMID:4353083 More... GO_REF:0000033 GO_REF:0000117, RGD:2302850, RGD:2302851, RGD:2302970 NCBI chr10:87,146,987...87,151,223
Ensembl chr10:87,146,901...87,151,221 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20487
    catalytic activity 6037
      hydrolase activity 2592
        hydrolase activity, acting on ester bonds 814
          phosphoric ester hydrolase activity 374
            phosphatase activity 283
              carbohydrate phosphatase activity 12
                sugar-phosphatase activity 11
                  sugar-terminal-phosphatase activity 3
                    glucose-6-phosphatase activity 3
paths to the root