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ONTOLOGY REPORT - ANNOTATIONS

Term:granuloma formation
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Accession:GO:0002432 term browser browse the term
Definition:The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.


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granuloma formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpb CCAAT/enhancer binding protein beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:4360613|PMID:17911624)		 UniProt
RGD		 PMID:17911624 GO_REF:0000024 MGI:4360613 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Unc13d unc-13 homolog D involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3628822 (PMID:17420270)		 Ensembl
RGD		 PMID:17420270 GO_REF:0000107 NCBI chr10:101,296,755...101,311,513
Ensembl chr10:101,296,776...101,311,687 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    immune system process 2823
      immune effector process 725
        granuloma formation 2
          negative regulation of granuloma formation 0
          positive regulation of granuloma formation 0
          regulation of granuloma formation + 0
Path 2
Term Annotations click to browse term
  biological_process 19692
    response to stimulus 10517
      response to stress 4178
        defense response 1860
          inflammatory response 843
            chronic inflammatory response 32
              granuloma formation 2
                negative regulation of granuloma formation 0
                positive regulation of granuloma formation 0
                regulation of granuloma formation + 0
paths to the root