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ONTOLOGY REPORT - ANNOTATIONS


Term:chronic inflammatory response
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Accession:GO:0002544 term browser browse the term
Definition:Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.



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chronic inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor IEP RGD PMID:20223282 RGD:4891140 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Camp cathelicidin antimicrobial peptide involved_in ISO (PMID:9182550) RGD PMID:9182550 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 IEP RGD PMID:10861753 RGD:4145481 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP RGD PMID:15104336 RGD:11526143 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP RGD PMID:17164972 RGD:2307142 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:23165424 RGD:7207259 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Ptges prostaglandin E synthase IEP RGD PMID:12707354 RGD:2300108 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G S100a7l2 S100 calcium binding protein A7 like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:176,506,300...176,509,196
Ensembl chr 2:176,506,300...176,509,196
JBrowse link
G S100a8 S100 calcium binding protein A8 IEP RGD PMID:8343166 RGD:633930 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 involved_in IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:8343166 PMID:21873635 RGD:633930, RGD:13792537 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G S100vp S100 calcium-binding protein, ventral prostate involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:176,748,273...176,751,624
Ensembl chr 2:176,748,273...176,751,624
JBrowse link
G Spn sialophorin IEP RGD PMID:10486239 RGD:2303982 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18674744) RGD PMID:18674744 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP RGD PMID:10706728 RGD:2313132 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vnn1 vanin 1 involved_in ISO (MGI:3029614|PMID:14966568) RGD PMID:14966568 MGI:3029614 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
chronic inflammatory response to antigenic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcy adenosylhomocysteinase IMP RGD PMID:11123369 RGD:1598898 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
JBrowse link
G Il10 interleukin 10 acts_upstream_of
involved_in
ISO
IEA
MGI:1857199 (MGI:3774790|PMID:12452830)
GO_REF:0000107
RGD
Ensembl
PMID:12452830 GO_REF:0000107 MGI:3774790 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta IEP RGD PMID:15050649 RGD:1626679 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist IEP RGD PMID:15050649 RGD:1626679 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Orm1 orosomucoid 1 IEP RGD PMID:16166348 RGD:2316639 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:14512626) RGD PMID:14512626 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
granuloma formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpb CCAAT/enhancer binding protein beta involved_in ISS
ISO
GO_REF:0000024
(MGI:4360613|PMID:17911624)
UniProt
RGD
PMID:17911624 GO_REF:0000024 MGI:4360613 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Unc13d unc-13 homolog D involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3628822 (MGI:3703574|PMID:17420270)
Ensembl
RGD
PMID:17420270 GO_REF:0000107 MGI:3703574 NCBI chr10:101,296,755...101,311,513
Ensembl chr10:101,296,776...101,311,687
JBrowse link
negative regulation of chronic inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857043 (MGI:5610078|PMID:25447050)
Ensembl
RGD
PMID:25447050 GO_REF:0000107 MGI:5610078 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (MGI:3693968|PMID:16769892), (MGI:3695768|PMID:16275384) RGD PMID:16275384 PMID:16769892 MGI:3693968 MGI:3695768 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Il4 interleukin 4 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:16869003 PMID:21873635 RGD:2317300, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:3763997|PMID:18006655) RGD PMID:18006655 MGI:3763997 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
negative regulation of chronic inflammatory response to antigenic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 acts_upstream_of_or_within ISO MGI:1857199 (MGI:3774790|PMID:12452830) RGD PMID:12452830 MGI:3774790 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
negative regulation of chronic inflammatory response to non-antigenic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cx3cr1 C-X3-C motif chemokine receptor 1 IMP RGD PMID:24447880 RGD:9491776 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
positive regulation of chronic inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ido1 indoleamine 2,3-dioxygenase 1 acts_upstream_of_or_within ISO MGI:3505776 (MGI:3789443|PMID:18436652) RGD PMID:18436652 MGI:3789443 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Pde5a phosphodiesterase 5A IMP RGD PMID:19129291 RGD:2314463 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
positive regulation of chronic inflammatory response to antigenic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lta lymphotoxin alpha acts_upstream_of_or_within ISO MGI:104798 (MGI:3690573|PMID:9834074) RGD PMID:9834074 MGI:3690573 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO MGI:104797 (MGI:3690573|PMID:9834074) RGD PMID:9834074 MGI:3690573 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
positive regulation of chronic inflammatory response to non-antigenic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3664521|PMID:16841096)
Ensembl
RGD
PMID:16841096 GO_REF:0000107 MGI:3664521 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    response to stimulus 10209
      response to stress 4153
        defense response 1728
          inflammatory response 815
            chronic inflammatory response 32
              chronic inflammatory response to antigenic stimulus + 7
              chronic inflammatory response to non-antigenic stimulus + 2
              granuloma formation + 2
              negative regulation of chronic inflammatory response + 6
              positive regulation of chronic inflammatory response + 5
              regulation of chronic inflammatory response + 11
paths to the root