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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of ceramide biosynthetic process
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Accession:GO:2000303 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process.
Synonyms:exact_synonym: regulation of ceramide anabolism;   regulation of ceramide biosynthesis;   regulation of ceramide formation;   regulation of ceramide synthesis

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regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101706228 ORM1-like protein 1 involved_in IEA UniProt GO_REF:0000104 GO_REF:0000117 NCBI chrNW_004624753:15,730,590...15,731,228 JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA UniProt GO_REF:0000104 GO_REF:0000117 NCBI chrNW_004624802:12,197,114...12,200,044
Ensembl chrNW_004624802:12,197,114...12,199,983 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) UniProt
MGI		 PMID:31880535 GO_REF:0000104 GO_REF:0000117 NCBI chrNW_004624795:3,210,382...3,216,130
Ensembl chrNW_004624795:3,209,605...3,217,539 		JBrowse link
G Paqr4 progestin and adipoQ receptor family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624824:711,755...715,815
Ensembl chrNW_004624824:712,355...715,700 		JBrowse link
G Prkcd protein kinase C delta involved_in ISO (PMID:17303575) UniProt PMID:17303575 NCBI chrNW_004624822:4,035,819...4,062,907
Ensembl chrNW_004624822:4,033,130...4,059,555 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in ISO (PMID:19506037) UniProt PMID:19506037 NCBI chrNW_004624754:8,466,049...8,553,721
Ensembl chrNW_004624754:8,465,981...8,550,666 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004624802:12,197,114...12,200,044
Ensembl chrNW_004624802:12,197,114...12,199,983 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004624795:3,210,382...3,216,130
Ensembl chrNW_004624795:3,209,605...3,217,539 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO (PMID:16118219) UniProt PMID:16118219 NCBI chrNW_004624801:6,253,219...6,257,128 JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (PMID:19364818) MGI PMID:19364818 NCBI chrNW_004624742:11,882,815...11,885,686
Ensembl chrNW_004624742:11,882,907...11,885,667 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (PMID:21177474) UniProt PMID:21177474 NCBI chrNW_004624801:8,895,138...8,901,848
Ensembl chrNW_004624801:8,895,836...8,903,952 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:18936091 GO_REF:0000118 RGD:6482750 NCBI chrNW_004624752:9,792,778...9,841,817
Ensembl chrNW_004624752:9,792,807...9,843,457 		JBrowse link
G Prkcd protein kinase C delta involved_in ISO (PMID:19279011) BHF-UCL PMID:19279011 NCBI chrNW_004624822:4,035,819...4,062,907
Ensembl chrNW_004624822:4,033,130...4,059,555 		JBrowse link
G Sirt3 sirtuin 3 involved_in ISO (PMID:26620563) UniProt PMID:26620563 NCBI chrNW_004624766:22,199,741...22,233,933
Ensembl chrNW_004624766:22,199,601...22,233,933 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:20096352 RGD:10041064 NCBI chrNW_004624746:17,857,779...17,948,469
Ensembl chrNW_004624746:17,920,835...17,948,468 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:16118219) UniProt PMID:16118219 NCBI chrNW_004624832:5,246,328...5,254,247
Ensembl chrNW_004624832:5,246,895...5,253,207 		JBrowse link
G Znf750 zinc finger protein 750 acts_upstream_of_or_within ISO (PMID:37115925) MGI PMID:37115925 NCBI chrNW_004624801:11,519,383...11,528,264
Ensembl chrNW_004624801:11,520,636...11,522,890 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17660
    regulation of biological process 11493
      regulation of cellular process 11166
        regulation of cellular component biogenesis 1088
          regulation of sphingolipid biosynthetic process 16
            regulation of ceramide biosynthetic process 14
              negative regulation of ceramide biosynthetic process + 3
              positive regulation of ceramide biosynthetic process + 8
              regulation of glucosylceramide biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 17660
    cellular process 17238
      metabolic process 11025
        primary metabolic process 9861
          lipid metabolic process 1267
            membrane lipid metabolic process 200
              membrane lipid biosynthetic process 137
                sphingolipid biosynthetic process 96
                  regulation of sphingolipid biosynthetic process 16
                    regulation of ceramide biosynthetic process 14
                      negative regulation of ceramide biosynthetic process + 3
                      positive regulation of ceramide biosynthetic process + 8
                      regulation of glucosylceramide biosynthetic process + 0
paths to the root