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ONTOLOGY REPORT - ANNOTATIONS

Term:Lsm1-7-Pat1 complex
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Accession:GO:1990726 term browser browse the term
Definition:A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway.


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Lsm1-7-Pat1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC126899.1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr19:40,146,975...40,147,500 JBrowse link
G Lsm1 LSM1 homolog, mRNA degradation associated part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:66,277,345...66,288,852
Ensembl chr16:66,277,345...66,288,852 		JBrowse link
G Lsm2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,843,467...3,847,217
Ensembl chr20:3,843,466...3,847,266 		JBrowse link
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:124,021,023...124,027,269
Ensembl chr 4:124,021,023...124,027,269 		JBrowse link
G Lsm5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:85,951,073...85,954,289
Ensembl chr 6:104,652,477...104,654,165
Ensembl chr 4:104,652,477...104,654,165 		JBrowse link
G Lsm5l1 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated like 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:1,339,769...1,340,198
Ensembl chr16:1,339,784...1,340,056 		JBrowse link
G Lsm7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:8,856,698...8,859,113
Ensembl chr 7:8,856,489...8,859,119 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20624
    protein-containing complex 6599
      Sm-like protein family complex 102
        Lsm1-7-Pat1 complex 7
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