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ONTOLOGY REPORT - ANNOTATIONS

Term:amyloid-beta clearance by transcytosis
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Accession:GO:0150093 term browser browse the term
Definition:The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.


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amyloid-beta clearance by transcytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cltc clathrin heavy chain involved_in ISO
IEA		 (PMID:26005850)
GO_REF:0000107		 RGD
Ensembl		 PMID:26005850 GO_REF:0000107 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO
IEA
IBA		 UniProtKB:Q13492 (PMID:26005850)
GO_REF:0000107
GO_REF:0000033
(PMID:20630619)		 RGD
Ensembl
GO_Central		 PMID:20630619 PMID:26005850 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO (PMID:26005850) RGD PMID:26005850 NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISO
IEA		 UniProtKB:Q07954 (PMID:26005850)
GO_REF:0000107
UniProtKB:P05067-PRO_0000000092 (PMID:26005850)		 RGD
Ensembl		 PMID:26005850 GO_REF:0000107 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557 		JBrowse link
G Rab11a RAB11a, member RAS oncogene family involved_in ISO UniProtKB:Q07954|UniProtKB:Q15907 (PMID:26005850) RGD PMID:26005850 NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISO UniProtKB:P62491|UniProtKB:Q07954 (PMID:26005850) RGD PMID:26005850 NCBI chr 7:14,521,448...14,534,589
Ensembl chr 7:14,521,368...14,534,593 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family involved_in ISO UniProtKB:Q07954 (PMID:26005850) RGD PMID:26005850 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    multicellular organismal process 8904
      transcytosis 26
        amyloid-beta clearance by transcytosis 7
Path 2
Term Annotations click to browse term
  biological_process 20075
    localization 5699
      establishment of localization 5002
        transport 4697
          vesicle-mediated transport 1632
            transcytosis 26
              amyloid-beta clearance by transcytosis 7
paths to the root