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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA 2'-O-methyltransferase activity
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Accession:GO:0106050 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide.
Synonyms:xref: Reactome:R-HSA-6788668 "TRMT13 2'-O-methylates adenosine-4 in tRNA";   Reactome:R-HSA-6788684 "TRMT13 2'-O-methylates cytidine-4 in tRNA";   Reactome:R-HSA-9024159 "FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe)"


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tRNA 2'-O-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ftsj1 FtsJ RNA 2'-O-methyltransferase 1 enables ISO (PMID:25404562), (PMID:26310293) RGD PMID:25404562 PMID:26310293 NCBI chr  X:14,243,684...14,256,555
Ensembl chr  X:14,244,050...14,252,030 		JBrowse link
G Trmt13 tRNA methyltransferase 13 homolog enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:204,533,630...204,547,711
Ensembl chr 2:204,533,632...204,546,843 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20483
    catalytic activity 6036
      catalytic activity, acting on a nucleic acid 630
        catalytic activity, acting on RNA 396
          catalytic activity, acting on a tRNA 136
            tRNA methyltransferase activity 31
              tRNA 2'-O-methyltransferase activity 2
                tRNA (uracil-2'-O-)-methyltransferase activity 0
Path 2
Term Annotations click to browse term
  molecular_function 20483
    catalytic activity 6036
      transferase activity 2397
        transferase activity, transferring one-carbon groups 218
          methyltransferase activity 208
            RNA methyltransferase activity 62
              RNA 2'-O-methyltransferase activity 9
                tRNA 2'-O-methyltransferase activity 2
                  tRNA (uracil-2'-O-)-methyltransferase activity 0
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