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ONTOLOGY REPORT - ANNOTATIONS

Term:presynaptic dense core vesicle exocytosis
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Accession:GO:0099525 term browser browse the term
Definition:The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels.

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presynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadps calcium dependent secretion activator involved_in ISO (PMID:25719439) SynGO PMID:25719439 NCBI chrNW_004936637:3,543,615...4,023,710
Ensembl chrNW_004936637:3,545,211...4,022,630 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in ISO (PMID:31679900) SynGO PMID:31679900 NCBI chrNW_004936618:3,678,400...4,047,994
Ensembl chrNW_004936618:3,606,524...4,047,711 		JBrowse link
G Snap25 synaptosome associated protein 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:9,198,744...9,279,854
Ensembl chrNW_004936485:9,195,110...9,279,920 		JBrowse link
G Syt10 synaptotagmin 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936607:2,940,607...2,995,178
Ensembl chrNW_004936607:2,940,466...2,994,344 		JBrowse link
G Unc13a unc-13 homolog A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936596:3,311,358...3,370,833
Ensembl chrNW_004936596:3,312,788...3,368,916 		JBrowse link
G Unc13b unc-13 homolog B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936524:3,320,859...3,369,865 JBrowse link
G Unc13c unc-13 homolog C involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936471:15,691,357...16,225,590
Ensembl chrNW_004936471:15,691,647...16,224,147 		JBrowse link
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2rx7 purinergic receptor P2X 7 involved_in ISO PMID:24037803 SynGO PMID:24037803 RGD:13702177 NCBI chrNW_004936558:3,106,819...3,149,689
Ensembl chrNW_004936558:3,108,283...3,149,765 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISO PMID:14627637 SynGO PMID:14627637 RGD:8554199 NCBI chrNW_004936588:5,198,659...5,210,430
Ensembl chrNW_004936588:5,198,394...5,214,603 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:2,990,367...2,995,935
Ensembl chrNW_004936596:2,989,804...2,998,305 		JBrowse link
G Unc13b unc-13 homolog B involved_in ISO PMID:31679900 SynGO PMID:31679900 RGD:155230690 NCBI chrNW_004936524:3,320,859...3,369,865 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16037
    cellular process 15650
      cellular localization 3419
        establishment of localization in cell 1977
          synaptic vesicle exocytosis 124
            calcium ion-regulated exocytosis of neurotransmitter 27
              presynaptic dense core vesicle exocytosis 10
                neuropeptide secretion from presynapse 0
                regulation of presynaptic dense core granule exocytosis 4
Path 2
Term Annotations click to browse term
  biological_process 16037
    biological regulation 11269
      regulation of biological process 10908
        signaling 6187
          cell-cell signaling 1294
            synaptic signaling 842
              trans-synaptic signaling 808
                anterograde trans-synaptic signaling 800
                  chemical synaptic transmission 800
                    neurotransmitter secretion 180
                      synaptic vesicle exocytosis 124
                        calcium ion-regulated exocytosis of neurotransmitter 27
                          presynaptic dense core vesicle exocytosis 10
                            neuropeptide secretion from presynapse 0
                            regulation of presynaptic dense core granule exocytosis 4
paths to the root