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ONTOLOGY REPORT - ANNOTATIONS

Term:mature conventional dendritic cell differentiation
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Accession:GO:0097029 term browser browse the term
Definition:The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.
Comment:Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.

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mature conventional dendritic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15845453) BHF-UCL PMID:15845453 NCBI chr12:45,928,212...45,930,897
Ensembl chr12:45,929,071...45,930,904 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:65,620,632...65,632,394
Ensembl chr16:65,620,665...65,632,984 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005 		JBrowse link
G LOC103242599 galectin-9 NOT|involved_in ISO (PMID:25754930) UniProt PMID:25754930 NCBI chr16:21,421,034...21,439,583 JBrowse link
G PRTN3 proteinase 3 involved_in ISO (PMID:16478888) UniProt PMID:16478888 NCBI chr 6:590,193...598,829 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19806
    developmental process 6822
      cellular developmental process 4575
        cell differentiation 4574
          leukocyte differentiation 683
            myeloid leukocyte differentiation 281
              mature conventional dendritic cell differentiation 5
Path 2
Term Annotations click to browse term
  biological_process 19806
    developmental process 6822
      cellular developmental process 4575
        cell differentiation 4574
          cell development 3260
            hemopoiesis 1051
              leukocyte differentiation 683
                mononuclear cell differentiation 554
                  dendritic cell differentiation 53
                    mature conventional dendritic cell differentiation 5
paths to the root