Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:dendritic cell differentiation
go back to main search page
Accession:GO:0097028 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.
Comment:Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.



show annotations for term's descendants           Sort by:
 
dendritic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axl Axl receptor tyrosine kinase involved_in ISO (PMID:19657094) RGD PMID:19657094 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Azi2 5-azacytidine induced 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5544312 (MGI:5543352|PMID:23610142)
Ensembl
RGD
PMID:23610142 GO_REF:0000107 MGI:5543352 NCBI chr 8:117,773,248...117,797,844
Ensembl chr 8:117,773,279...117,797,847
JBrowse link
G Batf3 basic leucine zipper ATF-like transcription factor 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:4441548|PMID:20351058)
UniProt
RGD
PMID:20351058 GO_REF:0000024 MGI:4441548 NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031
JBrowse link
G Cd40lg CD40 ligand IMP RGD PMID:18384807 RGD:2313415 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Csf2 colony stimulating factor 2 involved_in IDA
ISO
(PMID:21149635) RGD PMID:21149635 PMID:20628067 PMID:8535150 RGD:5131511, RGD:5131521 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 involved_in ISO (MGI:3795633|PMID:18469816) RGD PMID:18469816 MGI:3795633 NCBI chr12:7,623,658...7,699,474
Ensembl chr12:7,623,930...7,699,474
JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO (PMID:19657094) RGD PMID:19657094 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gata1 GATA binding protein 1 acts_upstream_of_or_within ISO (MGI:3763343|PMID:17505015) RGD PMID:17505015 MGI:3763343 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:21149635) RGD PMID:21149635 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Irf8 interferon regulatory factor 8 involved_in ISO (MGI:3654212|PMID:12461077) RGD PMID:12461077 MGI:3654212 NCBI chr19:48,790,483...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:3620486|PMID:16034130)
PMID:21873635
UniProt
RGD
PMID:16034130 PMID:21873635 GO_REF:0000024 MGI:3620486, RGD:13792537 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:11602640) RGD PMID:11602640 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5298324|PMID:21753080)
UniProt
RGD
PMID:21753080 GO_REF:0000024 MGI:5298324 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
JBrowse link
Langerhans cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb6 integrin subunit beta 6 acts_upstream_of_or_within ISO MGI:1338035 (MGI:3836488|PMID:19118215) RGD PMID:19118215 MGI:3836488 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Itgb8 integrin subunit beta 8 acts_upstream_of_or_within ISO MGI:96615 (MGI:3836488|PMID:19118215) RGD PMID:19118215 MGI:3836488 NCBI chr 6:140,124,997...140,208,254
Ensembl chr 6:140,127,203...140,208,476
JBrowse link
mature conventional dendritic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) RGD PMID:15845453 MGI:3576832 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (MGI:3576832|PMID:15845453) RGD PMID:15845453 MGI:3576832 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
ISS
(PMID:16478888)
(MGI:4839888|PMID:19845798)
GO_REF:0000024
RGD
UniProt
PMID:16478888 PMID:19845798 GO_REF:0000024 MGI:4839888 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:25754930) RGD PMID:25754930 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Prtn3 proteinase 3 involved_in ISO (PMID:16478888) RGD PMID:16478888 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944
JBrowse link
myeloid dendritic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:5441724|PMID:22992524)
UniProt
RGD
PMID:22992524 GO_REF:0000024 MGI:5441724 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051
JBrowse link
G Batf2 basic leucine zipper ATF-like transcription factor 2 involved_in ISO (MGI:5441724|PMID:22992524) RGD PMID:22992524 MGI:5441724 NCBI chr 1:203,467,291...203,479,428
Ensembl chr 1:203,468,097...203,475,889
JBrowse link
G Batf3 basic leucine zipper ATF-like transcription factor 3 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
(MGI:3815335|PMID:19008445)
MGI:3817232 (MGI:5562510|PMID:23913046)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19008445 PMID:23913046 GO_REF:0000024 GO_REF:0000107 MGI:3815335 MGI:5562510 NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV involved_in ISO
ISS
(PMID:17909078)
GO_REF:0000024
RGD
UniProt
PMID:17909078 GO_REF:0000024 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Cd86 CD86 molecule IEP RGD PMID:21039614 RGD:4892198 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Csf2 colony stimulating factor 2 involved_in
acts_upstream_of_or_within
ISO (PMID:16116184)
(MGI:2180258|PMID:12021780)
RGD PMID:12021780 PMID:16116184 MGI:2180258 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in ISO
IEA
(MGI:5319610|PMID:17713547)
GO_REF:0000107
RGD
Ensembl
PMID:17713547 GO_REF:0000107 MGI:5319610 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 involved_in ISO (PMID:11944995) RGD PMID:11944995 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15922563 RGD:2303773 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086
JBrowse link
G Il4 interleukin 4 involved_in IBA
ISO
PMID:21873635
(PMID:16116184)
RGD PMID:16116184 PMID:21873635 RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Irf4 interferon regulatory factor 4 involved_in
acts_upstream_of_or_within
ISO (MGI:5441724|PMID:22992524)
MGI:2387941 (MGI:3045824|PMID:15184678)
RGD PMID:15184678 PMID:22992524 MGI:3045824 MGI:5441724 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070
JBrowse link
G Ltbr lymphotoxin beta receptor acts_upstream_of_or_within ISO MGI:2384140 (MGI:5562510|PMID:23913046) RGD PMID:23913046 MGI:5562510 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539
JBrowse link
G Notch2 notch receptor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3617328 (MGI:5562510|PMID:23913046)
Ensembl
RGD
PMID:23913046 GO_REF:0000107 MGI:5562510 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Pirb paired Ig-like receptor B acts_upstream_of_or_within ISO MGI:2180757 (MGI:2180258|PMID:12021780) RGD PMID:12021780 MGI:2180258 Ensembl chr 1:65,499,195...65,506,666 JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:2449306 (MGI:5562510|PMID:23913046) RGD PMID:23913046 MGI:5562510 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:3583755 (MGI:5562510|PMID:23913046) RGD PMID:23913046 MGI:5562510 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit acts_upstream_of_or_within ISO MGI:2179544 (MGI:2677080|PMID:14499111), (MGI:70877|PMID:7845467) RGD PMID:7845467 PMID:14499111 MGI:2677080 MGI:70877 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Spi1 Spi-1 proto-oncogene acts_upstream_of_or_within ISO MGI:1930970 (MGI:1352309|PMID:10648399) RGD PMID:10648399 MGI:1352309 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:3719583 (MGI:3760597|PMID:17938236) RGD PMID:17938236 MGI:3760597 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within ISO MGI:2384513 (MGI:3760597|PMID:17938236) RGD PMID:17938236 MGI:3760597 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tnfsf9 TNF superfamily member 9 IDA RGD PMID:18687212 RGD:2317345 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345
JBrowse link
G Traf6 TNF receptor associated factor 6 acts_upstream_of_or_within ISO MGI:2678775 (MGI:2677080|PMID:14499111) RGD PMID:14499111 MGI:2677080 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Ubd ubiquitin D involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19028597)
Ensembl
UniProt
RGD
PMID:19028597 GO_REF:0000024 GO_REF:0000107 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639
JBrowse link
negative regulation of dendritic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:20702625) BHF-UCL PMID:20702625 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G Tmem176a transmembrane protein 176A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4835631|PMID:20501748)
RGD PMID:20501748 PMID:21873635 MGI:4835631, RGD:13792537 NCBI chr 4:77,774,940...77,778,620
Ensembl chr 4:77,774,843...77,778,620
JBrowse link
G Tmem176b transmembrane protein 176B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4835631|PMID:20501748)
RGD PMID:20501748 PMID:21873635 MGI:4835631, RGD:13792537 NCBI chr 4:77,766,928...77,774,740
Ensembl chr 4:77,766,928...77,774,384
JBrowse link
G Zbtb46 zinc finger and BTB domain containing 46 acts_upstream_of_or_within ISO MGI:5320483 (MGI:5320487|PMID:22615127) RGD PMID:22615127 MGI:5320487 NCBI chr 3:168,497,294...168,567,799
Ensembl chr 3:168,499,583...168,568,782
JBrowse link
plasmacytoid dendritic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf8 interferon regulatory factor 8 involved_in ISO (MGI:3641477|PMID:12538667) RGD PMID:12538667 MGI:3641477 NCBI chr19:48,790,483...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Slamf9 SLAM family member 9 acts_upstream_of_or_within ISO MGI:6364884 (MGI:6356667|PMID:31346085) RGD PMID:31346085 MGI:6356667 NCBI chr13:84,941,896...84,944,749
Ensembl chr13:84,941,982...84,944,748
JBrowse link
positive regulation of dendritic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IEA
(PMID:15944249)
GO_REF:0000107
RGD
Ensembl
PMID:15944249 GO_REF:0000107 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Cd40lg CD40 ligand IDA RGD PMID:18384807 RGD:2313415 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:15944249) RGD PMID:15944249 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
JBrowse link
G Lgals1 galectin 1 NOT|involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
JBrowse link
G Lgals3 galectin 3 NOT|involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Zbtb46 zinc finger and BTB domain containing 46 acts_upstream_of_or_within ISO MGI:5320483 (MGI:5320487|PMID:22615127) RGD PMID:22615127 MGI:5320487 NCBI chr 3:168,497,294...168,567,799
Ensembl chr 3:168,499,583...168,568,782
JBrowse link
regulation of dendritic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpb CCAAT/enhancer binding protein beta involved_in ISO RNAcentral:URS00000B7E30_10090 (MGI:5749907|PMID:26526992) RGD PMID:26526992 MGI:5749907 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 involved_in ISO (PMID:20008523) BHF-UCL PMID:20008523 NCBI chr20:4,905,309...4,914,593 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19812
    cellular process 18617
      cellular developmental process 4595
        cell differentiation 4499
          leukocyte differentiation 621
            mononuclear cell differentiation 481
              dendritic cell differentiation 52
                mature conventional dendritic cell differentiation 5
                myeloid dendritic cell differentiation + 25
                negative regulation of dendritic cell differentiation 4
                plasmacytoid dendritic cell differentiation + 2
                positive regulation of dendritic cell differentiation 7
                regulation of dendritic cell differentiation + 12
Path 2
Term Annotations click to browse term
  biological_process 19812
    developmental process 6948
      anatomical structure development 6361
        multicellular organism development 5787
          system development 5427
            animal organ development 4181
              hematopoietic or lymphoid organ development 1045
                hemopoiesis 993
                  leukocyte differentiation 621
                    mononuclear cell differentiation 481
                      dendritic cell differentiation 52
                        mature conventional dendritic cell differentiation 5
                        myeloid dendritic cell differentiation + 25
                        negative regulation of dendritic cell differentiation 4
                        plasmacytoid dendritic cell differentiation + 2
                        positive regulation of dendritic cell differentiation 7
                        regulation of dendritic cell differentiation + 12
paths to the root