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ONTOLOGY REPORT - ANNOTATIONS

Term:cerebrospinal fluid circulation
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Accession:GO:0090660 term browser browse the term
Definition:The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional.
Synonyms:exact_synonym: CSF circulation;   CSF flow;   cerebrospinal fluid flow

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cerebrospinal fluid circulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP4 aquaporin 4 involved_in ISO (MGI:5435611|PMID:22896675) UniProt PMID:22896675 MGI:5435611 NCBI chr18:53,729,143...53,742,916
Ensembl chr18:53,729,186...53,743,156 		JBrowse link
G CCDC39 coiled-coil domain 39 molecular ruler complex subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28289722)
(PMID:29317443)
(PMID:21515572)		 Ensembl
MGI		 PMID:21515572 PMID:28289722 PMID:29317443 GO_REF:0000107 NCBI chr15:8,730,456...8,789,379
Ensembl chr15:8,731,278...8,788,523 		JBrowse link
G CFAP221 cilia and flagella associated protein 221 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18039845)
(PMID:32704025)		 Ensembl
MGI		 PMID:18039845 PMID:32704025 GO_REF:0000107 NCBI chr10:10,666,903...10,780,316
Ensembl chr10:10,666,906...10,779,914 		JBrowse link
G CFAP43 cilia and flagella associated protein 43 acts_upstream_of_or_within ISO (PMID:31884020) MGI PMID:31884020 NCBI chr 9:97,179,767...97,283,267
Ensembl chr 9:97,179,647...97,283,225 		JBrowse link
G CFAP45 cilia and flagella associated protein 45 acts_upstream_of_or_within ISO (PMID:33139725) MGI PMID:33139725 NCBI chr20:4,036,029...4,078,608
Ensembl chr20:4,050,311...4,078,587 		JBrowse link
G CFAP53 cilia and flagella associated protein 53 acts_upstream_of_or_within ISO (PMID:33347437) MGI PMID:33347437 NCBI chr18:30,690,451...30,731,711
Ensembl chr18:30,691,006...30,725,354 		JBrowse link
G CFAP54 cilia and flagella associated protein 54 acts_upstream_of_or_within ISO (PMID:32704025) MGI PMID:32704025 NCBI chr11:91,853,456...92,226,841 JBrowse link
G CWH43 cell wall biogenesis 43 C-terminal homolog acts_upstream_of_or_within ISO (PMID:33459505) MGI PMID:33459505 NCBI chr27:1,199,363...1,281,422
Ensembl chr27:1,199,370...1,281,308 		JBrowse link
G DAW1 dynein assembly factor with WD repeats 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28289722) Ensembl
MGI		 PMID:28289722 GO_REF:0000107 NCBI chr10:113,890,514...113,948,610
Ensembl chr10:113,890,976...113,948,761 		JBrowse link
G DNAAF11 dynein axonemal assembly factor 11 acts_upstream_of_or_within ISO (PMID:27353389) MGI PMID:27353389 NCBI chr 8:127,010,303...127,103,343
Ensembl chr 8:127,008,619...127,103,300 		JBrowse link
G DNAH9 dynein axonemal heavy chain 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33347437) Ensembl
MGI		 PMID:33347437 GO_REF:0000107 NCBI chr16:10,947,254...11,316,414
Ensembl chr16:10,948,014...11,317,291 		JBrowse link
G JHY junctional cadherin complex regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23906841), (PMID:29211732) Ensembl
MGI		 PMID:23906841 PMID:29211732 GO_REF:0000107 NCBI chr 1:114,275,896...114,354,819
Ensembl chr 1:114,276,335...114,352,816 		JBrowse link
G KATNIP katanin interacting protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26714646) Ensembl
MGI		 PMID:26714646 GO_REF:0000107 NCBI chr 5:25,252,470...25,484,330
Ensembl chr 5:25,252,561...25,484,541 		JBrowse link
G LOC103217787 sperm-associated antigen 16 protein acts_upstream_of_or_within ISO (PMID:17323374) MGI PMID:17323374 NCBI chr10:99,044,097...100,215,884 JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6393053|PMID:25775275)
(MGI:5913033|PMID:28392297)		 ARUK-UCL
Ensembl		 PMID:25775275 PMID:28392297 GO_REF:0000107 MGI:5913033 MGI:6393053 NCBI chr16:46,889,454...46,910,776
Ensembl chr16:46,888,942...46,910,842 		JBrowse link
G ODAD3 outer dynein arm docking complex subunit 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31383820) Ensembl
MGI		 PMID:31383820 GO_REF:0000107 NCBI chr 6:10,349,063...10,360,292
Ensembl chr 6:10,349,069...10,360,250 		JBrowse link
G ODAD4 outer dynein arm docking complex subunit 4 acts_upstream_of_or_within ISO (PMID:27486780) MGI PMID:27486780 NCBI chr16:64,297,983...64,333,421 JBrowse link
G SPEF2 sperm flagellar 2 acts_upstream_of_or_within ISO (PMID:32704025) MGI PMID:32704025 NCBI chr 4:34,466,825...34,652,272
Ensembl chr 4:34,466,931...34,652,289 		JBrowse link
G ULK4 unc-51 like kinase 4 acts_upstream_of_or_within ISO (PMID:27445138) MGI PMID:27445138 NCBI chr22:2,731,174...3,398,885
Ensembl chr22:2,731,308...3,398,912 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    multicellular organismal process 7280
      system process 2179
        nervous system process 1441
          cerebrospinal fluid circulation 19
Path 2
Term Annotations click to browse term
  biological_process 16925
    cellular process 15870
      microtubule-based process 997
        microtubule-based movement 462
          cilium movement 240
            epithelial cilium movement involved in extracellular fluid movement 47
              cerebrospinal fluid circulation 19
paths to the root