CFAP45 (cilia and flagella associated protein 45) - Rat Genome Database

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Gene: CFAP45 (cilia and flagella associated protein 45) Chlorocebus sabaeus
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Symbol: CFAP45
Name: cilia and flagella associated protein 45
RGD ID: 18413185
Description: ENCODES a protein that exhibits AMP binding (ortholog); INVOLVED IN cerebrospinal fluid circulation (ortholog); epithelial cilium movement involved in determination of left/right asymmetry (ortholog); establishment of left/right asymmetry (ortholog); ASSOCIATED WITH autoimmune interstitial lung, joint, and kidney disease (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN 9+0 motile cilium (ortholog); 9+2 motile cilium (ortholog); axonemal B tubule inner sheath (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cilia- and flagella-associated protein 45; coiled-coil domain-containing protein 19, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1204,036,029 - 4,078,608 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl204,050,311 - 4,078,587 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660383,107,682 - 3,136,838 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
CFAP45
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1204,036,029 - 4,078,608 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl204,050,311 - 4,078,587 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660383,107,682 - 3,136,838 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CFAP45
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381159,872,364 - 159,900,165 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1159,872,364 - 159,900,165 (-)EnsemblGRCh38hg38GRCh38
GRCh371159,842,154 - 159,869,955 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361158,108,778 - 158,136,530 (-)NCBINCBI36Build 36hg18NCBI36
Celera1132,910,587 - 132,938,343 (-)NCBICelera
Cytogenetic Map1q23.2NCBI
HuRef1131,198,847 - 131,226,612 (-)NCBIHuRef
CHM1_11161,237,490 - 161,265,234 (-)NCBICHM1_1
T2T-CHM13v2.01159,009,376 - 159,037,231 (-)NCBIT2T-CHM13v2.0
Cfap45
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391172,348,697 - 172,373,437 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1172,348,368 - 172,373,437 (+)EnsemblGRCm39 Ensembl
GRCm381172,521,130 - 172,545,870 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,520,801 - 172,545,870 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,451,261 - 174,476,001 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,357,811 - 174,382,544 (+)NCBIMGSCv36mm8
Celera1175,374,886 - 175,400,082 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.91NCBI
Cfap45
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81387,521,831 - 87,545,236 (+)NCBIGRCr8
mRatBN7.21384,989,474 - 85,012,880 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1384,981,728 - 85,012,878 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1387,492,710 - 87,516,101 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01388,892,981 - 88,916,374 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01386,077,721 - 86,101,112 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01390,909,551 - 90,932,958 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,909,486 - 90,932,961 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,428,824 - 95,452,275 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,527,708 - 88,551,091 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1384,598,511 - 84,621,911 (+)NCBICelera
Cytogenetic Map13q24NCBI
Cfap45
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546811,672,462 - 11,699,245 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546811,672,332 - 11,711,395 (-)NCBIChiLan1.0ChiLan1.0
CFAP45
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2189,954,134 - 89,982,186 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1189,694,157 - 89,722,160 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01135,223,885 - 135,251,829 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11139,144,630 - 139,172,558 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1139,144,634 - 139,172,558 (-)Ensemblpanpan1.1panPan2
CFAP45
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13822,245,879 - 22,269,363 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3822,254,472 - 22,269,322 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3822,323,607 - 22,347,206 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03822,368,843 - 22,392,770 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3822,368,757 - 22,392,729 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.03822,668,511 - 22,692,064 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03823,079,342 - 23,103,004 (+)NCBIUU_Cfam_GSD_1.0
Cfap45
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050586,015,680 - 6,044,107 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936740710,076 - 738,701 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936740710,076 - 738,766 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CFAP45
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl490,593,858 - 90,627,800 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1490,593,864 - 90,626,660 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2498,569,705 - 98,596,559 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Cfap45
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247941,352,445 - 1,379,961 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247941,344,107 - 1,380,069 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 6
Low 32 16 54
Below cutoff 4 4

Sequence


RefSeq Acc Id: ENSCSAT00000000506   ⟹   ENSCSAP00000015555
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl204,050,311 - 4,078,587 (+)Ensembl
RefSeq Acc Id: XM_007976552   ⟹   XP_007974743
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1204,036,029 - 4,078,608 (+)NCBI
Vero_WHO_p1.0NW_0236660383,107,682 - 3,136,838 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007976554   ⟹   XP_007974745
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1204,050,322 - 4,078,608 (+)NCBI
Vero_WHO_p1.0NW_0236660383,108,598 - 3,136,838 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037997703   ⟹   XP_037853631
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660383,115,221 - 3,136,838 (+)NCBI
RefSeq Acc Id: XM_037997705   ⟹   XP_037853633
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660383,118,464 - 3,136,838 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007974743 (Get FASTA)   NCBI Sequence Viewer  
  XP_007974745 (Get FASTA)   NCBI Sequence Viewer  
  XP_037853631 (Get FASTA)   NCBI Sequence Viewer  
  XP_037853633 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015555.1
RefSeq Acc Id: XP_007974743   ⟸   XM_007976552
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S3W6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007974745   ⟸   XM_007976554
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S3W6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015555   ⟸   ENSCSAT00000000506
RefSeq Acc Id: XP_037853631   ⟸   XM_037997703
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S3W6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037853633   ⟸   XM_037997705
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002489 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000506.1 UniProtKB/TrEMBL
InterPro CFAP45 UniProtKB/TrEMBL
  TPH_dom UniProtKB/TrEMBL
NCBI Gene CFAP45 ENTREZGENE
PANTHER CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 45 UniProtKB/TrEMBL
  PTHR15504 UniProtKB/TrEMBL
Pfam TPH UniProtKB/TrEMBL
UniProt A0A0D9S3W6 ENTREZGENE, UniProtKB/TrEMBL