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ONTOLOGY REPORT - ANNOTATIONS

Term:BAT3 complex
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Accession:GO:0071818 term browser browse the term
Definition:A protein complex found in mammals that transfers tail-anchored (TA) proteins from SGTA to GET3 (ASNA1/TRC4) for targeting to the endoplasmic reticulum membrane. Also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD). Consists of BAG6 (BAT3) and its cofactors GET4 (TRC35) and UBL4A.
Synonyms:exact_synonym: BAG6-UBL4A-TRC35 complex;   Bag6 complex
 related_synonym: BAT3-TRC35-UBL4A complex
 never_in_taxon: NCBITaxon:4890 ! Ascomycota


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BAT3 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG6 BAG cochaperone 6 part_of
located_in		 IDA
IEA
IBA
IPI		 (PMID:20676083), (PMID:21636303), (PMID:25535373)
(PMID:25535373)		 BHF-UCL
TreeGrafter
GO_Central
ComplexPortal		 PMID:20676083 PMID:21636303 PMID:25535373 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:31,639,028...31,652,661
Ensembl chr 6:31,639,028...31,652,705 		JBrowse link
G GET4 guided entry of tail-anchored proteins factor 4 located_in
part_of		 IPI
IBA
IDA		 (PMID:25535373)
(PMID:20676083), (PMID:21636303), (PMID:25535373)		 ComplexPortal
GO_Central
UniProt		 PMID:20676083 PMID:21636303 PMID:25535373 GO_REF:0000033 NCBI chr 7:876,554...896,436
Ensembl chr 7:876,554...896,436 		JBrowse link
G UBL4A ubiquitin like 4A part_of
located_in		 IDA
IPI
IBA		 (PMID:20676083), (PMID:21636303), (PMID:25535373)
(PMID:25535373)		 UniProt
ComplexPortal
GO_Central		 PMID:20676083 PMID:21636303 PMID:25535373 GO_REF:0000033 NCBI chr  X:154,483,717...154,486,615
Ensembl chr  X:154,483,717...154,486,615 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20718
    protein-containing complex 7461
      ER membrane insertion complex 14
        BAT3 complex 3
Path 2
Term Annotations click to browse term
  cellular_component 20718
    cellular anatomical entity 20332
      intracellular anatomical structure 16223
        cytoplasm 12730
          cytosol 5671
            ER membrane insertion complex 14
              BAT3 complex 3
paths to the root