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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:ER membrane insertion complex
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Accession:GO:0072379 term browser browse the term
Definition:A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast.
Synonyms:exact_synonym: endoplasmic reticulum membrane insertion complex



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BAT3 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag6 BAG cochaperone 6 part_of ISO
ISS
IEA
IBA
(PMID:20676083), (PMID:21636303), (PMID:25535373)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
RGD
UniProt
Ensembl
GO_Central
PMID:20676083 PMID:21636303 PMID:25535373 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,680,607...3,693,329
Ensembl chr20:3,680,607...3,693,329
JBrowse link
G Get4 guided entry of tail-anchored proteins factor 4 part_of ISO
IBA
(PMID:20676083), (PMID:21636303), (PMID:25535373)
GO_REF:0000033
RGD
GO_Central
PMID:20676083 PMID:21636303 PMID:25535373 GO_REF:0000033 NCBI chr12:20,490,861...20,508,096
Ensembl chr12:20,490,861...20,555,240
JBrowse link
G Ubl4a ubiquitin-like 4A part_of ISO
IBA
ISS
(PMID:20676083), (PMID:21636303), (PMID:25535373)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:20676083 PMID:21636303 PMID:25535373 GO_REF:0000024 GO_REF:0000033 NCBI chr  X:157,302,528...157,305,380
Ensembl chr  X:157,304,254...157,305,380
JBrowse link
multi-pass translocon complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc47 coiled-coil domain containing 47 part_of ISS
ISO
IEA
GO_REF:0000024
(PMID:36261522)
(PMID:36261528)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:36261522 PMID:36261528 GO_REF:0000024 GO_REF:0000107 NCBI chr10:91,630,101...91,648,626
Ensembl chr10:91,630,106...91,648,626
JBrowse link
G Ncln nicalin part_of IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:36261522)
(PMID:36261528)
GO_REF:0000117
Ensembl
UniProt
RGD
PMID:36261522 PMID:36261528 GO_REF:0000024 GO_REF:0000107 GO_REF:0000117 NCBI chr 7:8,862,324...8,872,699
Ensembl chr 7:8,862,751...8,872,698
JBrowse link
G Nomo1 Nodal modulator 1 part_of ISO
IEA
(PMID:36261522)
GO_REF:0000117
RGD
UniProt
PMID:36261522 GO_REF:0000117 NCBI chr 1:105,641,867...105,692,708
Ensembl chr 1:105,641,879...105,692,707
JBrowse link
G Rab5if RAB5 interacting factor part_of ISO
IEA
(PMID:36261522)
(PMID:36261528)
GO_REF:0000107
RGD
Ensembl
PMID:36261522 PMID:36261528 GO_REF:0000107 NCBI chr 3:165,818,060...165,828,071
Ensembl chr 3:165,816,588...165,828,067
JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 part_of ISS
ISO
IEA
GO_REF:0000024
(PMID:36261522)
(PMID:36261528)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:36261522 PMID:36261528 GO_REF:0000024 GO_REF:0000107 NCBI chr13:81,993,172...82,016,496
Ensembl chr13:81,993,097...82,017,201
JBrowse link
G Tmem147 transmembrane protein 147 part_of ISO
IEA
(PMID:36261522)
(PMID:36261528)
GO_REF:0000107
RGD
Ensembl
PMID:36261522 PMID:36261528 GO_REF:0000107 NCBI chr 1:95,104,448...95,106,268
Ensembl chr 1:95,104,452...95,106,283
JBrowse link
G Wdr83os WD repeat domain 83 opposite strand part_of ISO (PMID:36261522)
(PMID:36261528)
RGD PMID:36261522 PMID:36261528 NCBI chr19:39,980,247...39,981,619
Ensembl chr19:39,980,247...39,982,737
JBrowse link
TRC complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:9,304,381...9,321,157
Ensembl chr 7:9,304,197...9,321,669
JBrowse link
G Sgtb small glutamine rich tetratricopeptide repeat co-chaperone beta part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:36,966,840...37,003,318
Ensembl chr 2:36,966,838...37,003,311
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21544
    protein-containing complex 6918
      ER membrane insertion complex 12
        BAT3 complex 3
        TRC complex 2
        multi-pass translocon complex 7
Path 2
Term Annotations click to browse term
  cellular_component 21544
    cellular anatomical structure 21390
      intracellular anatomical structure 15814
        cytoplasm 12699
          cytosol 4674
            ER membrane insertion complex 12
              BAT3 complex 3
              TRC complex 2
              multi-pass translocon complex 7
paths to the root