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ONTOLOGY REPORT - ANNOTATIONS
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Term:
regulation of serotonin uptake
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Accession:
GO:0051611
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Definition:
Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell.
Synonyms:
exact_synonym:
regulation of 5-HT uptake; regulation of 5-hydroxytryptamine uptake; regulation of 5HT uptake; regulation of serotonin import
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Rat (5)
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Pig (6)
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Genes (5)
regulation of serotonin uptake
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
ITGB3
integrin subunit beta 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857
negative regulation of serotonin uptake
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
GPM6B
glycoprotein M6B
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr X:12,258,386...12,429,883
G
NOS1
nitric oxide synthase 1
involved_in
ISO
(PMID:17452640)
UniProt
PMID:17452640
NCBI chr11:112,642,374...112,673,882
G
SLC18A1
solute carrier family 18 member A1
ISO
G-protein mediated uptake inhibition
RGD
PMID:16926160
RGD:5130998
NCBI chr 8:18,214,703...18,250,025
Ensembl chr 8:18,214,701...18,249,731
G
SNCA
synuclein alpha
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 7:38,083,154...38,194,068
Ensembl chr 7:38,081,509...38,191,479
Term paths to the root
one shortest
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one shortest and longest
all
Path 1
Term
Annotations
biological_process
19806
localization
5944
regulation of localization
2330
regulation of transport
1884
regulation of neurotransmitter transport
134
regulation of neurotransmitter uptake
21
regulation of serotonin uptake
5
negative regulation of serotonin uptake
+
4
positive regulation of serotonin uptake
0
Path 2
Term
Annotations
biological_process
19806
localization
5944
establishment of localization
5256
transport
4402
nitrogen compound transport
1842
monoamine transport
104
serotonin transport
29
serotonin uptake
13
regulation of serotonin uptake
5
negative regulation of serotonin uptake
+
4
positive regulation of serotonin uptake
0