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ONTOLOGY REPORT - ANNOTATIONS

Term:serotonin uptake
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Accession:GO:0051610 term browser browse the term
Definition:The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.
Synonyms:exact_synonym: 5-HT uptake;   5-hydroxytryptamine uptake;   5HT uptake;   serotonin import

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serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC18A1 solute carrier family 18 member A1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:19008227 GO_REF:0000107 RGD:5131091 NCBI chr 8:18,214,703...18,250,025
Ensembl chr 8:18,214,701...18,249,731 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20007701 GO_REF:0000107 RGD:5130957 NCBI chr 9:110,039,783...110,078,822
Ensembl chr 9:110,040,391...110,076,647 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:42,216,187...42,219,665
Ensembl chr 9:42,216,568...42,218,166 		JBrowse link
G SLC18B1 solute carrier family 18 member B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:40,721,153...40,750,423
Ensembl chr13:40,721,186...40,750,526 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:87,744,600...87,780,846
Ensembl chr13:87,745,023...87,781,073 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:87,835,077...87,881,410
Ensembl chr13:87,833,430...87,881,081 		JBrowse link
G SLC22A3 solute carrier family 22 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:87,971,305...88,076,468
Ensembl chr13:87,971,392...88,074,946 		JBrowse link
G SLC29A4 solute carrier family 29 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:16,429,879...16,450,580
Ensembl chr28:16,429,413...16,450,324 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 involved_in ISO
IEA		 RGD
Ensembl
TreeGrafter		 PMID:12944413 GO_REF:0000107 GO_REF:0000118 RGD:1580638 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
negative regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPM6B glycoprotein M6B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:12,258,386...12,429,883 JBrowse link
G NOS1 nitric oxide synthase 1 involved_in ISO (PMID:17452640) UniProt PMID:17452640 NCBI chr11:112,642,374...112,673,882 JBrowse link
G SLC18A1 solute carrier family 18 member A1 ISO G-protein mediated uptake inhibition RGD PMID:16926160 RGD:5130998 NCBI chr 8:18,214,703...18,250,025
Ensembl chr 8:18,214,701...18,249,731 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,083,154...38,194,068
Ensembl chr 7:38,081,509...38,191,479 		JBrowse link
regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGB3 integrin subunit beta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19806
    cellular process 19328
      cellular localization 4108
        establishment of localization in cell 2061
          neurotransmitter reuptake 29
            serotonin uptake 13
              negative regulation of serotonin uptake + 4
              positive regulation of serotonin uptake 0
              regulation of serotonin uptake + 5
Path 2
Term Annotations click to browse term
  biological_process 19806
    localization 5944
      establishment of localization 5256
        transport 4402
          nitrogen compound transport 1842
            monoamine transport 104
              serotonin transport 29
                serotonin uptake 13
                  negative regulation of serotonin uptake + 4
                  positive regulation of serotonin uptake 0
                  regulation of serotonin uptake + 5
paths to the root