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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of actin nucleation
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Accession:GO:0051126 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
Synonyms:exact_synonym: down regulation of actin nucleation;   downregulation of actin nucleation
 narrow_synonym: inhibition of actin nucleation

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negative regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpin actin related protein 2/3 complex inhibitor involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624768:16,956,263...16,964,328
Ensembl chrNW_004624768:16,952,247...16,964,384 		JBrowse link
G Coro1a coronin 1A involved_in ISO (PMID:17442961) UniProt PMID:17442961 NCBI chrNW_004624782:13,106,416...13,111,394
Ensembl chrNW_004624782:13,105,153...13,111,357 		JBrowse link
negative regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1b coronin 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:19,080,541...19,087,128
Ensembl chrNW_004624767:19,080,451...19,090,419 		JBrowse link
G Ctnna2 catenin alpha 2 involved_in ISO (PMID:30013181) UniProt PMID:30013181 NCBI chrNW_004624749:22,332,750...23,546,165
Ensembl chrNW_004624749:22,333,710...23,412,593 		JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 involved_in ISO (PMID:32128961) UniProt PMID:32128961 NCBI chrNW_004624742:12,369,903...12,463,184
Ensembl chrNW_004624742:12,369,834...12,463,215 		JBrowse link
G Gmfb glia maturation factor beta involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624731:14,790,338...14,804,163
Ensembl chrNW_004624731:14,790,384...14,804,163 		JBrowse link
G Gmfg glia maturation factor gamma acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23727094) MGI
TreeGrafter		 PMID:23727094 GO_REF:0000118 NCBI chrNW_004624794:12,668,720...12,676,471
Ensembl chrNW_004624794:12,668,618...12,676,502 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO (PMID:17318189) ParkinsonsUK-UCL PMID:17318189 NCBI chrNW_004624747:22,876,183...22,897,557
Ensembl chrNW_004624747:22,876,276...22,896,584 		JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in ISO PMID:18297063 UniProt PMID:18297063 RGD:8554748 NCBI chrNW_004624752:9,880,773...9,895,270
Ensembl chrNW_004624752:9,880,670...9,895,230 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15135
    cellular process 14753
      negative regulation of cellular process 4839
        negative regulation of cellular component organization 733
          negative regulation of supramolecular fiber organization 173
            negative regulation of actin nucleation 9
              negative regulation of Arp2/3 complex-mediated actin nucleation 7
Path 2
Term Annotations click to browse term
  biological_process 15135
    cellular process 14753
      cellular component organization or biogenesis 6274
        cellular component organization 6087
          organelle organization 3337
            cytoskeleton organization 1376
              regulation of cytoskeleton organization 506
                regulation of actin cytoskeleton organization 330
                  regulation of actin filament organization 261
                    regulation of actin nucleation 31
                      negative regulation of actin nucleation 9
                        negative regulation of Arp2/3 complex-mediated actin nucleation 7
paths to the root