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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of supramolecular fiber organization
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Accession:GO:1902904 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.
Comment:HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro
Synonyms:narrow_synonym: inhibition of fibril organisation;   inhibition of fibril organization
 related_synonym: down regulation of fibril organisation;   down regulation of fibril organization;   downregulation of fibril organisation;   downregulation of fibril organization;   negative regulation of fibril organisation


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negative regulation of supramolecular fiber organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clasp2 cytoplasmic linker associated protein 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 8:122,555,532...122,736,934
Ensembl chr 8:122,555,524...122,737,587 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISO (PMID:23921388) RGD PMID:23921388 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Togaram2 TOG array regulator of axonemal microtubules 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 6:29,491,183...29,549,004
Ensembl chr 6:29,491,040...29,548,977 		JBrowse link
actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4933400A11Rik similar to RIKEN cDNA 4933400A11 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr  X:27,950,539...27,955,623 JBrowse link
G Avil advillin involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:64,711,403...64,729,436 		JBrowse link
G Capg capping actin protein, gelsolin like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:106,152,890...106,170,672 		JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:195,008,035...195,053,100
Ensembl chr 2:195,008,039...195,053,100 		JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:46,944,040...46,979,930
Ensembl chr 4:46,895,701...46,979,938 		JBrowse link
G Capza3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:174,660,446...174,661,659
Ensembl chr 4:174,659,693...174,665,846 		JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:156,718,619...156,818,623
Ensembl chr 5:156,650,432...156,818,619 		JBrowse link
G Dmtn dematin actin binding protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:52,087,667...52,111,956
Ensembl chr15:52,087,667...52,112,128 		JBrowse link
G Gsn gelsolin involved_in ISO
IEA 		(PMID:19666531)
(PMID:23325791)
GO_REF:0000107
GO_REF:0000043 		RGD
Ensembl
UniProt		 PMID:19666531 PMID:23325791 GO_REF:0000043 GO_REF:0000107 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:38,982,671...39,035,850 		JBrowse link
G Myh9 myosin, heavy chain 9 NOT|involved_in ISO (PMID:23325791) RGD PMID:23325791 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963 		JBrowse link
G Scin scinderin involved_in ISO
IEA 		(PMID:19666531)
GO_REF:0000043 		RGD
UniProt		 PMID:19666531 GO_REF:0000043 NCBI chr 6:62,836,641...62,915,287
Ensembl chr 6:62,836,641...62,915,287 		JBrowse link
G Spta1 spectrin, alpha, erythrocytic 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:88,735,833...88,811,697
Ensembl chr13:88,735,833...88,811,697 		JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:33,639,020...33,703,890
Ensembl chr 3:33,607,210...33,703,889 		JBrowse link
G Sptb spectrin, beta, erythrocytic involved_in IEA GO_REF:0000104
GO_REF:0000043 		UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 6:101,043,512...101,170,389
Ensembl chr 6:101,045,216...101,170,278 		JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 involved_in IEA GO_REF:0000104
GO_REF:0000043 		UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr14:108,042,629...108,217,884
Ensembl chr14:108,042,629...108,217,836 		JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 involved_in IEA GO_REF:0000043
GO_REF:0000104 		UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:211,432,373...211,473,016
Ensembl chr 1:211,432,373...211,473,306 		JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 involved_in IEA GO_REF:0000104
GO_REF:0000043 		UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:91,778,379...91,865,970
Ensembl chr 1:91,778,380...91,865,049 		JBrowse link
G Tpm1 tropomyosin 1 IDA RGD PMID:15779917 RGD:1600523 NCBI chr 8:76,516,654...76,543,661
Ensembl chr 8:76,511,871...76,543,468 		JBrowse link
G Tpm1_v7 tropomyosin 1, variant 7 IDA RGD PMID:15779917 RGD:1600523
G Vil1 villin 1 involved_in ISO
IEA 		(PMID:16921170), (PMID:17182858), (PMID:19808673)
GO_REF:0000043
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:16921170 PMID:17182858 PMID:19808673 GO_REF:0000043 GO_REF:0000107 NCBI chr 9:83,440,248...83,467,963
Ensembl chr 9:83,440,248...83,467,961 		JBrowse link
G Vill villin-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:127,654,491...127,672,742
Ensembl chr 8:127,654,595...127,672,753 		JBrowse link
barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4933400A11Rik similar to RIKEN cDNA 4933400A11 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000002
GO_REF:0000104 		GO_Central
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 Ensembl chr  X:27,950,539...27,955,623 JBrowse link
G Add1 adducin 1 involved_in ISO
IBA 		(PMID:8626479)
GO_REF:0000033 		RGD
GO_Central		 PMID:8626479 GO_REF:0000033 NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732 		JBrowse link
G Add2 adducin 2 involved_in ISO
IBA
IEA 		(PMID:8626479)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:8626479 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:120,001,977...120,101,090
Ensembl chr 4:120,002,054...120,101,091 		JBrowse link
G Add3 adducin 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:262,152,722...262,260,504
Ensembl chr 1:262,154,996...262,260,504 		JBrowse link
G Avil advillin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:64,711,403...64,729,436 		JBrowse link
G Capg capping actin protein, gelsolin like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:106,152,890...106,170,672 		JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 involved_in
acts_upstream_of_or_within 		IEA
ISO
IBA 		GO_REF:0000104
(PMID:17656356)
GO_REF:0000002
GO_REF:0000033 		UniProt
RGD
InterPro
GO_Central		 PMID:17656356 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 2:195,008,035...195,053,100
Ensembl chr 2:195,008,039...195,053,100 		JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IEA
IBA 		GO_REF:0000002
GO_REF:0000033
GO_REF:0000104 		InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 4:46,944,040...46,979,930
Ensembl chr 4:46,895,701...46,979,938 		JBrowse link
G Capza3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IEA
IBA 		GO_REF:0000104
GO_REF:0000002
GO_REF:0000033 		UniProt
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 4:174,660,446...174,661,659
Ensembl chr 4:174,659,693...174,665,846 		JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in
acts_upstream_of_or_within 		IEA
ISO
IBA 		GO_REF:0000104
(PMID:17656356)
GO_REF:0000002
GO_REF:0000033 		UniProt
RGD
InterPro
GO_Central		 PMID:17656356 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 5:156,718,619...156,818,623
Ensembl chr 5:156,650,432...156,818,619 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:15558031), (PMID:20532239), (PMID:23314863)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:15558031 PMID:20532239 PMID:23314863 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:172,119,497...172,291,670
Ensembl chr 4:172,119,497...172,218,160 		JBrowse link
G Flii FLII, actin remodeling protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:45,893,566...45,907,547
Ensembl chr10:45,893,572...45,907,491 		JBrowse link
G Gsn gelsolin involved_in IEA
IBA 		GO_REF:0000104
GO_REF:0000033 		UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:38,982,671...39,035,850 		JBrowse link
G Rdx radixin IDA RGD PMID:2500445 RGD:8693627 NCBI chr 8:61,275,792...61,348,260
Ensembl chr 8:61,274,460...61,333,967 		JBrowse link
G Scin scinderin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:62,836,641...62,915,287
Ensembl chr 6:62,836,641...62,915,287 		JBrowse link
G Svil supervillin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:57,343,910...57,539,508
Ensembl chr17:57,343,910...57,462,660 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in IBA
ISO 		GO_REF:0000033
(PMID:18837697) 		GO_Central
RGD		 PMID:18837697 GO_REF:0000033 NCBI chr 7:127,595,210...127,607,821
Ensembl chr 7:127,595,210...127,607,105 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in IBA
ISO 		GO_REF:0000033
(PMID:18837697) 		GO_Central
RGD		 PMID:18837697 GO_REF:0000033 NCBI chr 8:115,723,980...115,737,025
Ensembl chr 8:115,723,970...115,737,025 		JBrowse link
G Vil1 villin 1 involved_in ISO
IEA 		(PMID:15272027)
GO_REF:0000107 		RGD
Ensembl		 PMID:15272027 GO_REF:0000107 NCBI chr 9:83,440,248...83,467,963
Ensembl chr 9:83,440,248...83,467,961 		JBrowse link
G Vill villin-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:127,654,491...127,672,742
Ensembl chr 8:127,654,595...127,672,753 		JBrowse link
negative regulation of actin filament bundle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 IMP RGD PMID:24093776 RGD:11570550 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353 		JBrowse link
G Dbn1 drebrin 1 IDA RGD PMID:8769857 RGD:2317774 NCBI chr17:9,155,729...9,170,121
Ensembl chr17:9,155,787...9,170,122 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA prevents phenylephrine-induced actin organization RGD PMID:9155015 RGD:2293527 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Pfn1 profilin 1 involved_in ISO
IEA 		(PMID:23153535)
GO_REF:0000107 		RGD
Ensembl		 PMID:23153535 GO_REF:0000107 NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,863,881...55,868,611 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA 		(PMID:17512523)
GO_REF:0000107 		RGD
Ensembl		 PMID:17512523 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304 		JBrowse link
G Rab40b Rab40b, member RAS oncogene family involved_in ISO
IEA 		(PMID:33999101)
GO_REF:0000107 		RGD
Ensembl		 PMID:33999101 GO_REF:0000107 NCBI chr10:107,129,801...107,157,375
Ensembl chr10:107,129,801...107,157,457 		JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 involved_in
acts_upstream_of_or_within 		ISS
ISO
IEA 		GO_REF:0000024
(PMID:19208628)
GO_REF:0000107 		BHF-UCL
RGD
Ensembl		 PMID:19208628 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:103,944,416...103,993,887
Ensembl chr 1:103,944,813...103,992,356 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 involved_in
acts_upstream_of_or_within 		ISS
ISO
IEA 		GO_REF:0000024
(PMID:19208628)
GO_REF:0000107 		BHF-UCL
RGD
Ensembl		 PMID:19208628 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:122,448,323...122,518,623
Ensembl chr 7:122,448,323...122,510,410 		JBrowse link
negative regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353 		JBrowse link
G Lima1 LIM domain and actin binding 1 involved_in ISO
ISS 		(PMID:12566430)
GO_REF:0000024 		RGD
UniProt		 PMID:12566430 GO_REF:0000024 NCBI chr 7:132,780,556...132,880,343
Ensembl chr 7:132,780,556...132,880,386 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in IEA
ISO 		GO_REF:0000107
(PMID:30568254) 		Ensembl
RGD		 PMID:30568254 GO_REF:0000107 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411 		JBrowse link
G Plekhh2 pleckstrin homology, MyTH4 and FERM domain containing H2 involved_in IBA
ISO
IEA 		GO_REF:0000033
(PMID:22832517)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:22832517 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:15,783,179...15,893,479
Ensembl chr 6:15,784,645...15,893,537 		JBrowse link
G Shroom2 shroom family member 2 acts_upstream_of_or_within ISO (PMID:17666436) RGD PMID:17666436 NCBI chr  X:25,308,163...25,480,194
Ensembl chr  X:25,308,163...25,479,385 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:21703590) 		Ensembl
RGD		 PMID:21703590 GO_REF:0000107 NCBI chr20:13,337,399...13,443,080
Ensembl chr20:13,339,108...13,443,079 		JBrowse link
G Swap70 switching B-cell complex subunit SWAP70 involved_in IEA
ISO 		GO_REF:0000107
(PMID:23921380) 		Ensembl
RGD		 PMID:23921380 GO_REF:0000107 NCBI chr 1:173,702,338...173,763,540
Ensembl chr 1:173,702,347...173,763,947 		JBrowse link
negative regulation of actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 IMP RGD PMID:8675693 RGD:7174724 NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732 		JBrowse link
G Arfgef1 ARF guanine nucleotide exchange factor 1 involved_in ISO
IEA
ISS 		(PMID:22084092)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:22084092 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:13,764,507...13,859,237
Ensembl chr 5:13,764,975...13,859,237 		JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3055492 (PMID:23716571) 		Ensembl
RGD		 PMID:23716571 GO_REF:0000107 NCBI chr 8:68,627,739...68,661,232
Ensembl chr 8:68,627,656...68,661,358 		JBrowse link
G Capn1 calpain 1 IMP RGD PMID:25653381 RGD:13792590 NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445 		JBrowse link
G Cyrib CYFIP related Rac1 interactor B involved_in ISO
IEA 		(PMID:30250061)
GO_REF:0000107 		RGD
Ensembl		 PMID:30250061 GO_REF:0000107 NCBI chr 7:97,524,941...97,649,846
Ensembl chr 7:97,523,121...97,649,853 		JBrowse link
G Fhod3 formin homology 2 domain containing 3 acts_upstream_of_or_within ISO (PMID:19706596) RGD PMID:19706596 NCBI chr18:16,267,830...16,700,508
Ensembl chr18:16,267,977...16,700,508 		JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr12:26,769,868...26,904,367
Ensembl chr12:26,769,961...26,904,296 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO
IEA 		(PMID:17318189)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:17318189 GO_REF:0000107 GO_REF:0000117 NCBI chr12:38,251,085...38,279,756
Ensembl chr12:38,251,086...38,279,654 		JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:18458160)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033
(PMID:17996375) 		RGD
Ensembl
InterPro
GO_Central		 PMID:17996375 PMID:18458160 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:232,381,720...232,500,834
Ensembl chr 1:232,445,658...232,500,839 		JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:28,587,770...28,617,212
Ensembl chr 8:28,587,770...28,616,993 		JBrowse link
G Kank3 KN motif and ankyrin repeat domains 3 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 7:15,296,538...15,309,838
Ensembl chr 7:15,296,585...15,311,408 		JBrowse link
G Kank4 KN motif and ankyrin repeat domains 4 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:118,516,994...118,581,024
Ensembl chr 5:118,517,971...118,581,002 		JBrowse link
G Mkks MKKS centrosomal shuttling protein acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:23716571) 		Ensembl
RGD		 PMID:23716571 GO_REF:0000107 NCBI chr 3:144,654,563...144,672,831
Ensembl chr 3:144,654,566...144,672,831 		JBrowse link
G Myadm myeloid-associated differentiation marker involved_in ISO
IEA 		(PMID:23264465)
GO_REF:0000107 		RGD
Ensembl		 PMID:23264465 GO_REF:0000107 NCBI chr 1:74,779,616...74,796,752
Ensembl chr 1:74,775,698...74,789,710 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA RGD PMID:17662049 RGD:7240703 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Pfn2 profilin 2 acts_upstream_of_or_within ISO (PMID:18001770) RGD PMID:18001770 NCBI chr 2:144,217,100...144,222,936
Ensembl chr 2:144,205,636...144,222,936 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:16940418)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:16940418 GO_REF:0000024 GO_REF:0000107 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO
IEA 		(PMID:19759280)
GO_REF:0000107 		RGD
Ensembl		 PMID:19759280 GO_REF:0000107 NCBI chr14:66,829,661...67,168,517
Ensembl chr14:66,829,661...67,167,146 		JBrowse link
G Ssh1 slingshot protein phosphatase 1 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr12:48,281,756...48,343,812
Ensembl chr12:48,281,756...48,343,812 		JBrowse link
G Ssh2 slingshot protein phosphatase 2 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:62,555,388...62,807,457
Ensembl chr10:62,555,460...62,807,453 		JBrowse link
G Ssh3 slingshot protein phosphatase 3 involved_in IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:210,986,604...210,994,975
Ensembl chr 1:210,986,606...210,994,284 		JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO ComplexPortal:CPX-1134 (PMID:22198949) RGD PMID:22198949 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tmsb15b2 thymosin beta 15B2 acts_upstream_of_or_within ISO (PMID:19233202) RGD PMID:19233202 NCBI chr  X:105,090,980...105,093,094
Ensembl chr  X:105,090,980...105,093,094 		JBrowse link
G Tmsb4x thymosin beta 4, X-linked involved_in ISO (PMID:1447300), (PMID:1999398) RGD PMID:1447300 PMID:1999398 NCBI chr  X:30,761,611...30,763,612
Ensembl chr  X:30,761,612...30,763,613 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in IEA
ISO
IMP 		GO_REF:0000002
(PMID:12807912)
GO_REF:0000117 		InterPro
RGD
UniProt		 PMID:12807912 PMID:33963280 GO_REF:0000002 GO_REF:0000117, RGD:596938166 NCBI chr 7:127,595,210...127,607,821
Ensembl chr 7:127,595,210...127,607,105 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in IEA
ISO 		GO_REF:0000002
(PMID:12807912)
GO_REF:0000117 		InterPro
RGD
UniProt		 PMID:12807912 GO_REF:0000002 GO_REF:0000117 NCBI chr 8:115,723,980...115,737,025
Ensembl chr 8:115,723,970...115,737,025 		JBrowse link
negative regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpin actin-related protein 2/3 complex inhibitor involved_in ISO
IEA
IBA 		(PMID:24132237)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033 		RGD
Ensembl
InterPro
GO_Central		 PMID:24132237 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:143,273,590...143,282,426
Ensembl chr 1:143,273,590...143,282,532 		JBrowse link
G Coro1a coronin 1A involved_in ISO
IEA 		(PMID:17442961)
GO_REF:0000107 		RGD
Ensembl		 PMID:17442961 GO_REF:0000107 NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:190,726,130...190,731,102 		JBrowse link
negative regulation of amyloid fibril formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISS
ISO 		GO_REF:0000024
(PMID:14741101) 		UniProt
RGD		 PMID:14741101 GO_REF:0000024 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Clu clusterin involved_in ISO
ISS
IEA 		(PMID:22179788)
(PMID:14741101)
GO_REF:0000024
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:14741101 PMID:22179788 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G Cryab crystallin, alpha B involved_in ISO
IEA 		(PMID:23106396)
GO_REF:0000107 		RGD
Ensembl		 PMID:23106396 GO_REF:0000107 NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 involved_in ISO UniProtKB:P05067-PRO_0000000093 (PMID:21126803) RGD PMID:21126803 NCBI chr 5:154,960,818...155,061,971
Ensembl chr 5:154,960,846...155,061,971 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:P05067|UniProtKB:P49768 (PMID:20005821) 		Ensembl
RGD		 PMID:20005821 GO_REF:0000107 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Mir31 microRNA 31 acts_upstream_of ISO UniProtKB:P05067 (PMID:32069773) RGD PMID:32069773 NCBI chr 5:108,714,849...108,714,954 JBrowse link
G Pfdn1 prefoldin subunit 1 involved_in ISO (PMID:23614719) RGD PMID:23614719 NCBI chr18:28,288,210...28,341,198
Ensembl chr18:28,287,913...28,341,123 		JBrowse link
G Pfdn2 prefoldin subunit 2 involved_in ISO (PMID:23614719) RGD PMID:23614719 NCBI chr13:86,305,037...86,323,008 JBrowse link
G Pfdn4 prefoldin subunit 4 involved_in ISO
IEA 		(PMID:23614719)
GO_REF:0000107 		RGD
Ensembl		 PMID:23614719 GO_REF:0000107 NCBI chr 3:179,721,765...179,729,901
Ensembl chr 3:179,719,344...179,729,901 		JBrowse link
G Pfdn5 prefoldin subunit 5 involved_in ISO
IEA 		(PMID:23614719)
GO_REF:0000107 		RGD
Ensembl		 PMID:23614719 GO_REF:0000107 NCBI chr 7:135,330,364...135,335,102
Ensembl chr 7:135,330,172...135,335,099 		JBrowse link
G Pfdn6 prefoldin subunit 6 involved_in ISO
IEA 		(PMID:23614719)
GO_REF:0000107 		RGD
Ensembl		 PMID:23614719 GO_REF:0000107 NCBI chr20:4,947,844...4,949,318
Ensembl chr20:4,947,844...4,949,318 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30617257) RGD PMID:30617257 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:20,144,334...20,151,779 		JBrowse link
G Vbp1 VHL binding protein 1 involved_in ISO (PMID:23614719) RGD PMID:23614719
negative regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1b coronin 1B involved_in IEA
ISO 		GO_REF:0000107
(PMID:17350576), (PMID:18775315) 		Ensembl
RGD		 PMID:17350576 PMID:18775315 GO_REF:0000107 NCBI chr 1:210,872,437...210,877,876
Ensembl chr 1:210,871,841...210,877,876 		JBrowse link
G Ctnna2 catenin alpha 2 involved_in ISO (PMID:30013181) RGD PMID:30013181 NCBI chr 4:110,852,265...112,001,351
Ensembl chr 4:110,852,265...112,001,365 		JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 involved_in ISO
IEA 		(PMID:32128961)
GO_REF:0000107 		RGD
Ensembl		 PMID:32128961 GO_REF:0000107 NCBI chr 2:237,608,202...237,666,465
Ensembl chr 2:237,604,068...237,666,465 		JBrowse link
G Gmfb glia maturation factor, beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:22,549,705...22,560,125
Ensembl chr15:22,547,034...22,560,308 		JBrowse link
G Gmfg glia maturation factor, gamma involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:23727094) 		GO_Central
RGD		 PMID:23727094 GO_REF:0000033 NCBI chr 1:92,856,154...92,866,722
Ensembl chr 1:92,854,995...92,866,723 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in IEA
ISO 		GO_REF:0000107
(PMID:17318189) 		Ensembl
RGD		 PMID:17318189 GO_REF:0000107 NCBI chr12:38,251,085...38,279,756
Ensembl chr12:38,251,086...38,279,654 		JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in IDA PMID:18297063 UniProt PMID:18297063 RGD:8554748 NCBI chr 7:112,676,890...112,697,275
Ensembl chr 7:112,677,322...112,697,257 		JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:16054028) 		Ensembl
RGD		 PMID:16054028 GO_REF:0000107 NCBI chr17:41,235,819...41,516,204
Ensembl chr17:41,236,229...41,516,221 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO
IEA 		(PMID:26466680)
GO_REF:0000107 		RGD
Ensembl		 PMID:26466680 GO_REF:0000107 NCBI chr19:50,481,911...50,496,672
Ensembl chr19:50,484,324...50,496,669 		JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO
IBA 		(PMID:30361697)
GO_REF:0000033 		RGD
GO_Central		 PMID:30361697 GO_REF:0000033 NCBI chr14:31,638,328...31,874,391
Ensembl chr14:31,638,328...31,683,987 		JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) RGD PMID:20498093 NCBI chr 4:150,912,863...150,998,301
Ensembl chr 4:150,912,395...150,998,301 		JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:16151019) 		Ensembl
RGD		 PMID:16151019 GO_REF:0000107 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:69,518,988...69,549,684 		JBrowse link
negative regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in
acts_upstream_of_or_within 		ISS
ISO
IBA 		GO_REF:0000024
(PMID:16525027)
GO_REF:0000033
(PMID:17192415)
(PMID:11166179) 		UniProt
RGD
GO_Central		 PMID:11166179 PMID:16525027 PMID:17192415 GO_REF:0000024 GO_REF:0000033 NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:10,043,010...10,065,037
Ensembl chr 7:10,043,010...10,065,210 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO
ISS
IEA 		(PMID:11912491)
GO_REF:0000024
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:11912491 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646 		JBrowse link
G Atxn7 ataxin 7 involved_in ISO
IEA 		(PMID:22100762)
GO_REF:0000107 		RGD
Ensembl		 PMID:22100762 GO_REF:0000107 NCBI chr15:13,547,859...13,693,311
Ensembl chr15:13,547,862...13,693,526 		JBrowse link
G Bbof1 basal body orientation factor 1 acts_upstream_of_or_within ISO (PMID:37494937) RGD PMID:37494937 NCBI chr 6:109,786,363...109,812,153
Ensembl chr 6:109,786,363...109,812,147 		JBrowse link
G Bmerb1 bMERB domain containing 1 involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
(PMID:25099998)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:25099998 GO_REF:0000033 GO_REF:0000107 NCBI chr10:2,286,999...2,453,890
Ensembl chr10:2,287,000...2,453,728 		JBrowse link
G Camsap1 calmodulin regulated spectrin-associated protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:29,144,318...29,206,382
Ensembl chr 3:29,144,318...29,204,184 		JBrowse link
G Camsap2 calmodulin regulated spectrin-associated protein family, member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:50,274,950...50,354,298
Ensembl chr13:50,274,950...50,354,298 		JBrowse link
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:6,440,959...6,464,582
Ensembl chr12:6,441,152...6,464,582 		JBrowse link
G Ccdc88c coiled-coil domain containing 88C acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:33929515) 		Ensembl
RGD		 PMID:33929515 GO_REF:0000107 NCBI chr 6:125,899,337...126,019,162
Ensembl chr 6:125,899,526...126,018,865 		JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISO
IEA
ISS 		(PMID:21215777)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:21215777 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:143,587,591...143,593,153
Ensembl chr 1:143,587,021...143,593,326 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
(PMID:16061649), (PMID:35029146)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:16061649 PMID:35029146 GO_REF:0000033 GO_REF:0000107 NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352 		JBrowse link
G Ckap2l cytoskeleton associated protein 2-like acts_upstream_of_or_within ISO (PMID:24260314) RGD PMID:24260314 NCBI chr 3:136,950,390...136,977,503
Ensembl chr 3:136,950,381...136,977,565 		JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in
acts_upstream_of_or_within 		ISO
IEA 		UniProtKB:O75122 (PMID:15631994), (PMID:16866869)
(PMID:11290329)
GO_REF:0000117 		RGD
UniProt		 PMID:11290329 PMID:15631994 PMID:16866869 GO_REF:0000117 NCBI chr13:32,046,362...32,267,954
Ensembl chr13:32,046,444...32,267,924 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 acts_upstream_of_or_within
involved_in 		IDA
ISO
IEA 		MGI:3693618 (PMID:11290329), (PMID:17113391)
GO_REF:0000117 		RGD
UniProt		 PMID:11290329 PMID:17113391 PMID:11290329 GO_REF:0000117, RGD:68300 NCBI chr 8:122,555,532...122,736,934
Ensembl chr 8:122,555,524...122,737,587 		JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 involved_in NAS PMID:11290329 UniProt PMID:11290329 RGD:68300 NCBI chr12:27,798,289...27,863,486
Ensembl chr12:27,799,524...27,863,484 		JBrowse link
G Diaph3 diaphanous-related formin 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:18458159) 		Ensembl
RGD		 PMID:18458159 GO_REF:0000107 NCBI chr15:68,951,992...69,421,623
Ensembl chr15:68,951,989...69,421,552 		JBrowse link
G Eml4 EMAP like 4 acts_upstream_of_or_within ISO (PMID:17196341) RGD PMID:17196341 NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:16,972,075...17,087,439 		JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:22726441)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:22726441 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:142,312,381...142,838,581
Ensembl chr  X:142,312,391...142,423,536 		JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 involved_in ISO (PMID:12584248) RGD PMID:12584248 NCBI chr14:84,169,398...84,175,514
Ensembl chr14:84,169,398...84,175,514 		JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:12584248) 		UniProt
RGD		 PMID:12584248 GO_REF:0000024 NCBI chr10:68,719,999...68,727,549
Ensembl chr10:68,719,999...68,727,171 		JBrowse link
G Hdac6 histone deacetylase 6 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:12486003) 		Ensembl
RGD		 PMID:12486003 GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:17,222,856...17,244,370 		JBrowse link
G Hdgfl3 HDGF like 3 involved_in ISS
ISO 		GO_REF:0000024
(PMID:19237540) 		UniProt
RGD		 PMID:19237540 GO_REF:0000024 NCBI chr 1:145,233,996...145,287,115
Ensembl chr 1:145,236,758...145,286,001 		JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO
IEA 		(PMID:10751153)
GO_REF:0000107 		RGD
Ensembl		 PMID:10751153 GO_REF:0000107 NCBI chr19:9,927,249...9,946,750
Ensembl chr19:9,927,249...9,946,738 		JBrowse link
G Map1a microtubule-associated protein 1A IDA RGD PMID:11896150 RGD:71122 NCBI chr 3:128,716,907...128,736,638
Ensembl chr 3:128,716,940...128,740,159 		JBrowse link
G Map1b microtubule-associated protein 1B IDA RGD PMID:11896150 RGD:71122 NCBI chr 2:32,551,423...32,644,471
Ensembl chr 2:32,551,423...32,657,094 		JBrowse link
G Map2 microtubule-associated protein 2 involved_in IMP PMID:11029056 CAFA PMID:11029056 RGD:12793013 NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459 		JBrowse link
G Map6d1 MAP6 domain containing 1 acts_upstream_of_or_within ISO (PMID:16837464) RGD PMID:16837464 NCBI chr11:94,238,552...94,244,781
Ensembl chr11:94,238,542...94,246,901 		JBrowse link
G Mid1 midline 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1915291 (PMID:15070402) 		Ensembl
RGD		 PMID:15070402 GO_REF:0000107 NCBI chr  X:27,678,248...28,053,049
Ensembl chr  X:27,681,867...27,906,105 		JBrowse link
G Mid1ip1 MID1 interacting protein 1 involved_in
acts_upstream_of_or_within 		ISS
ISO 		GO_REF:0000024
MGI:1100537 (PMID:15070402) 		UniProt
RGD		 PMID:15070402 GO_REF:0000024 NCBI chr  X:14,733,539...14,735,859
Ensembl chr  X:14,732,830...14,739,079 		JBrowse link
G Nav3 neuron navigator 3 involved_in ISO
IEA 		(PMID:25678558)
GO_REF:0000107 		RGD
Ensembl		 PMID:25678558 GO_REF:0000107 NCBI chr 7:46,938,577...47,726,839
Ensembl chr 7:46,940,670...47,504,893 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:21703590) 		Ensembl
RGD		 PMID:21703590 GO_REF:0000107 NCBI chr20:13,337,399...13,443,080
Ensembl chr20:13,339,108...13,443,079 		JBrowse link
G Spef1 sperm flagellar 1 involved_in ISO (PMID:16206169) RGD PMID:16206169 NCBI chr 3:138,843,679...138,849,762 JBrowse link
G Stmn2 stathmin 2 involved_in ISO
IEA 		(PMID:18452648)
GO_REF:0000107 		RGD
Ensembl		 PMID:18452648 GO_REF:0000107 NCBI chr 2:95,112,017...95,159,642
Ensembl chr 2:95,112,019...95,159,335 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
IEA 		(PMID:12639963)
GO_REF:0000107 		RGD
Ensembl		 PMID:12639963 GO_REF:0000107 NCBI chr10:62,871,198...62,989,049
Ensembl chr10:62,871,198...62,957,595 		JBrowse link
G Tpx2 TPX2, microtubule nucleation factor involved_in ISO
IEA 		(PMID:26414402)
GO_REF:0000107 		RGD
Ensembl		 PMID:26414402 GO_REF:0000107 NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:161,778,742...161,820,724 		JBrowse link
G Trim54 tripartite motif-containing 54 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:10953002) 		Ensembl
RGD		 PMID:10953002 GO_REF:0000107 NCBI chr 6:30,959,306...30,978,475
Ensembl chr 6:30,959,306...30,978,475 		JBrowse link
G Ttbk2 tau tubulin kinase 2 involved_in ISO
IEA 		(PMID:26323690)
GO_REF:0000107 		RGD
Ensembl		 PMID:26323690 GO_REF:0000107 NCBI chr 3:128,144,851...128,256,630
Ensembl chr 3:128,144,851...128,258,738 		JBrowse link
G Wdr47 WD repeat domain 47 acts_upstream_of_or_within IEA
ISO
IMP 		GO_REF:0000107
MGI:6102912 (PMID:29078390) 		Ensembl
RGD		 PMID:29078390 PMID:29078390 GO_REF:0000107, RGD:21201271 NCBI chr 2:198,914,977...198,975,844
Ensembl chr 2:198,914,940...198,975,841 		JBrowse link
negative regulation of microtubule nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef7 Rho guanine nucleotide exchange factor 7 involved_in ISS
ISO 		GO_REF:0000024
(PMID:27012601) 		UniProt
RGD		 PMID:27012601 GO_REF:0000024 NCBI chr16:84,373,123...84,484,759
Ensembl chr16:84,373,123...84,484,597 		JBrowse link
negative regulation of microtubule polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Capzb capping actin protein of muscle Z-line subunit beta acts_upstream_of_or_within ISO (PMID:19806181) RGD PMID:19806181 NCBI chr 5:156,718,619...156,818,623
Ensembl chr 5:156,650,432...156,818,619 		JBrowse link
G Cdh5 cadherin 5 involved_in ISO
IEA 		(PMID:23159740)
GO_REF:0000107 		RGD
Ensembl		 PMID:23159740 GO_REF:0000107 NCBI chr19:821,875...860,931
Ensembl chr19:822,464...860,822 		JBrowse link
G Clip3 CAP-GLY domain containing linker protein 3 involved_in ISO
IEA
ISS 		(PMID:15262990)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:15262990 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:94,674,492...94,690,643
Ensembl chr 1:94,674,661...94,690,642 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A involved_in IEA
ISO 		GO_REF:0000107
(PMID:17906291) 		Ensembl
RGD		 PMID:17906291 GO_REF:0000107 NCBI chr11:47,360,824...47,479,033
Ensembl chr11:47,360,850...47,479,033 		JBrowse link
G Eml2 EMAP like 2 involved_in ISO
IEA
ISS 		(PMID:11694528)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:11694528 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:87,955,924...87,987,366
Ensembl chr 1:87,955,606...87,987,366 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 IMP RGD PMID:17435176 RGD:5508373 NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:163,389,464...163,397,918 		JBrowse link
G Inpp5j inositol polyphosphate-5-phosphatase J involved_in IMP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:16280363 GO_REF:0000033, RGD:2312436 NCBI chr14:82,597,789...82,608,930
Ensembl chr14:82,597,790...82,609,678 		JBrowse link
G LOC102551813 stathmin-like involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:96,217,025...96,222,032
Ensembl chr 5:151,964,351...151,970,842 		JBrowse link
G Map2 microtubule-associated protein 2 involved_in IMP PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459 		JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 involved_in ISO
IEA 		(PMID:11943150)
GO_REF:0000107 		RGD
Ensembl		 PMID:11943150 GO_REF:0000107 NCBI chr 3:162,679,020...162,707,167
Ensembl chr 3:162,673,195...162,711,210 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 IDA RGD PMID:16982696 RGD:1642763 NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231 		JBrowse link
G Snca synuclein alpha involved_in ISO
IEA 		(PMID:21127069)
GO_REF:0000107 		RGD
Ensembl		 PMID:21127069 GO_REF:0000107 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315 		JBrowse link
G Stmn1 stathmin 1 involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000107
(PMID:15652749) 		Ensembl
RGD		 PMID:15652749 GO_REF:0000107 NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842 		JBrowse link
G Stmn2 stathmin 2 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:18452648), (PMID:21215777) 		UniProt
Ensembl
RGD		 PMID:18452648 PMID:21215777 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:95,112,017...95,159,642
Ensembl chr 2:95,112,019...95,159,335 		JBrowse link
G Tbcd tubulin folding cofactor D involved_in ISO
IEA 		(PMID:10831612), (PMID:20740604)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:10831612 PMID:20740604 GO_REF:0000107 GO_REF:0000117 NCBI chr10:107,215,626...107,372,398
Ensembl chr10:107,215,633...107,372,402 		JBrowse link
G Tubb4a tubulin, beta 4A class IVa involved_in ISO
IEA 		(PMID:10211825)
GO_REF:0000107 		RGD
Ensembl		 PMID:10211825 GO_REF:0000107 NCBI chr 9:2,004,836...2,012,281
Ensembl chr 9:2,004,840...2,012,286 		JBrowse link
negative regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO
IEA 		(PMID:12847114)
GO_REF:0000107 		RGD
Ensembl		 PMID:12847114 GO_REF:0000107 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:147,137,797...147,153,967 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:24777478 RGD:13204833 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495 		JBrowse link
negative regulation of stress fiber assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arap1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 involved_in ISO
IEA 		(PMID:11804590)
GO_REF:0000107 		RGD
Ensembl		 PMID:11804590 GO_REF:0000107 NCBI chr 1:165,160,701...165,226,219
Ensembl chr 1:165,160,678...165,226,218 		JBrowse link
G Arhgap28 Rho GTPase activating protein 28 involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
(PMID:25211221)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:25211221 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:115,277,849...115,444,789
Ensembl chr 9:115,279,734...115,445,008 		JBrowse link
G Arhgap6 Rho GTPase activating protein 6 involved_in ISO
IEA 		(PMID:10699171)
GO_REF:0000107 		RGD
Ensembl		 PMID:10699171 GO_REF:0000107 NCBI chr  X:28,525,912...29,062,344
Ensembl chr  X:28,525,917...29,061,244 		JBrowse link
G Arhgef18 Rho/Rac guanine nucleotide exchange factor 18 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr12:6,192,958...6,300,997
Ensembl chr12:6,128,661...6,300,997 		JBrowse link
G Cgnl1 cingulin-like 1 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr 8:81,154,169...81,305,598
Ensembl chr 8:81,140,091...81,305,747 		JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in ISO (PMID:24859005) RGD PMID:24859005 NCBI chr13:32,046,362...32,267,954
Ensembl chr13:32,046,444...32,267,924 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24859005) RGD PMID:24859005 NCBI chr 8:122,555,532...122,736,934
Ensembl chr 8:122,555,524...122,737,587 		JBrowse link
G Coro2b coronin 2B acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:4419137 (PMID:29162887) 		Ensembl
RGD		 PMID:29162887 GO_REF:0000107 NCBI chr 8:71,802,329...71,912,739
Ensembl chr 8:71,802,329...71,912,739 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein involved_in ISO
IEA 		(PMID:17932950)
GO_REF:0000107 		RGD
Ensembl		 PMID:17932950 GO_REF:0000107 NCBI chr16:61,954,177...62,374,819
Ensembl chr16:61,995,001...62,374,819 		JBrowse link
G F11r F11 receptor involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr13:86,406,229...86,429,819
Ensembl chr13:86,406,218...86,429,816 		JBrowse link
G Frmd7 FERM domain containing 7 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:23967341) 		Ensembl
RGD		 PMID:23967341 GO_REF:0000107 NCBI chr  X:135,261,272...135,308,178
Ensembl chr  X:135,261,029...135,308,786 		JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in ISO
IEA 		(PMID:12556481)
GO_REF:0000107 		RGD
Ensembl		 PMID:12556481 GO_REF:0000107 NCBI chr10:60,974,183...60,995,047
Ensembl chr10:60,973,950...60,995,046 		JBrowse link
G LOC102551813 stathmin-like involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:96,217,025...96,222,032
Ensembl chr 5:151,964,351...151,970,842 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821 		JBrowse link
G Mir138-1 microRNA 138-1 involved_in ISO (PMID:20232393) RGD PMID:20232393 NCBI chr 8:131,178,434...131,178,532
Ensembl chr 8:131,178,434...131,178,532 		JBrowse link
G Mir138-2 microRNA 138-2 involved_in ISO (PMID:20232393) RGD PMID:20232393 NCBI chr19:10,680,133...10,680,214 JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:22696064) RGD PMID:22696064 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:98,588,303...98,588,387 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:21347332) RGD PMID:21347332 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Myoc myocilin involved_in ISO
ISS
IEA 		(PMID:17984096)
GO_REF:0000024
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:17984096 GO_REF:0000024 GO_REF:0000107 NCBI chr13:77,509,963...77,520,361
Ensembl chr13:77,509,963...77,520,361 		JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 IDA RGD PMID:21712390 RGD:7245493 NCBI chr 2:184,762,242...184,765,176
Ensembl chr 2:184,762,245...184,771,428 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO
IEA 		(PMID:25753039)
GO_REF:0000107 		RGD
Ensembl		 PMID:25753039 GO_REF:0000107 NCBI chr11:82,212,896...82,273,803
Ensembl chr11:82,212,951...82,273,803 		JBrowse link
G Pfn1 profilin 1 involved_in ISO
IEA 		(PMID:23153535)
GO_REF:0000107 		RGD
Ensembl		 PMID:23153535 GO_REF:0000107 NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,863,881...55,868,611 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 involved_in ISO
IEA 		(PMID:24859005)
GO_REF:0000107 		RGD
Ensembl		 PMID:24859005 GO_REF:0000107 NCBI chr11:68,321,738...68,540,724
Ensembl chr11:68,355,959...68,540,734 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO (PMID:11038173) RGD PMID:11038173 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347 		JBrowse link
G Ppfia1 PTPRF interacting protein alpha 1 acts_upstream_of_or_within ISO
IEA 		(PMID:22266902)
GO_REF:0000107 		RGD
Ensembl		 PMID:22266902 GO_REF:0000107 NCBI chr 1:209,070,608...209,147,740
Ensembl chr 1:209,070,608...209,150,265 		JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:12052877 RGD:1299363 NCBI chr 4:33,936,949...34,258,927
Ensembl chr 4:33,988,827...34,258,927 		JBrowse link
G Rhpn1 rhophilin, Rho GTPase binding protein 1 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:25071083) 		GO_Central
RGD		 PMID:25071083 GO_REF:0000033 NCBI chr 7:109,272,676...109,283,444
Ensembl chr 7:109,272,715...109,283,444 		JBrowse link
G Rhpn2 rhophilin, Rho GTPase binding protein 2 acts_upstream_of_or_within
involved_in 		ISO
IEA
IBA 		(PMID:25071083)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:25071083 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:97,128,054...97,188,803
Ensembl chr 1:97,127,697...97,188,803 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IDA RGD PMID:11094076 RGD:1581790 NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689 		JBrowse link
G Stmn1 stathmin 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:22194864) 		UniProt
RGD		 PMID:22194864 GO_REF:0000024 NCBI chr 4:98,037,620...98,039,320
Ensembl chr 4:98,033,251...98,039,323 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 acts_upstream_of_or_within ISO
IEA 		(PMID:24632071)
GO_REF:0000107 		RGD
Ensembl		 PMID:24632071 GO_REF:0000107 NCBI chr 9:57,937,873...58,225,372
Ensembl chr 9:57,937,873...58,225,372 		JBrowse link
G Tmsb15b2 thymosin beta 15B2 acts_upstream_of_or_within ISO (PMID:19233202) RGD PMID:19233202 NCBI chr  X:105,090,980...105,093,094
Ensembl chr  X:105,090,980...105,093,094 		JBrowse link
G Was WASP actin nucleation promoting factor involved_in ISO
IEA 		(PMID:8625410)
GO_REF:0000107 		RGD
Ensembl		 PMID:8625410 GO_REF:0000107 NCBI chr  X:17,077,057...17,085,802
Ensembl chr  X:17,073,314...17,085,802 		JBrowse link
G Wasf2 WASP family member 2 involved_in ISO
IEA 		(PMID:21107423)
GO_REF:0000107 		RGD
Ensembl		 PMID:21107423 GO_REF:0000107 NCBI chr 5:150,620,733...150,685,943
Ensembl chr 5:150,620,733...150,685,943 		JBrowse link
pointed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmod1 leiomodin 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:49,305,693...49,347,970
Ensembl chr13:49,305,830...49,348,116 		JBrowse link
G Lmod2 leiomodin 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:54,032,974...54,040,670
Ensembl chr 4:54,032,974...54,040,666 		JBrowse link
G Lmod3 leiomodin 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:131,400,643...131,415,411
Ensembl chr 4:131,400,423...131,415,342 		JBrowse link
G Tmod1 tropomodulin 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:65,112,062...65,189,563
Ensembl chr 5:65,134,132...65,189,561 		JBrowse link
G Tmod2 tropomodulin 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:85,197,222...85,250,627
Ensembl chr 8:85,196,226...85,246,371 		JBrowse link
G Tmod3 tropomodulin 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:85,131,295...85,191,477
Ensembl chr 8:85,131,299...85,191,341 		JBrowse link
G Tmod4 tropomodulin 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:185,384,547...185,389,549
Ensembl chr 2:185,384,795...185,389,992 		JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc2 actin related protein 2/3 complex, subunit 2 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 9:83,269,884...83,300,610
Ensembl chr 9:83,269,932...83,305,409 		JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:23704350 RGD:11570555 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353 		JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtpn myotrophin involved_in ISO
IBA
ISS 		(PMID:16895918)
GO_REF:0000033
GO_REF:0000024 		RGD
GO_Central
UniProt		 PMID:16895918 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:65,126,390...65,153,803
Ensembl chr 4:65,115,980...65,153,924 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      negative regulation of cellular process 5649
        negative regulation of cellular component organization 814
          negative regulation of supramolecular fiber organization 188
            negative regulation of actin filament bundle assembly + 43
            negative regulation of actin filament depolymerization + 50
            negative regulation of actin filament polymerization + 67
            negative regulation of actin nucleation + 9
            negative regulation of amyloid fibril formation 13
            negative regulation of cardiac myofibril assembly 1
            negative regulation of microtubule depolymerization + 39
            negative regulation of microtubule polymerization + 17
            negative regulation of myosin II filament organization + 0
            negative regulation of sarcomere organization 2
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      cellular component organization or biogenesis 7050
        cellular component organization 6802
          regulation of cellular component organization 2735
            negative regulation of cellular component organization 814
              negative regulation of supramolecular fiber organization 188
                negative regulation of actin filament bundle assembly + 43
                negative regulation of actin filament depolymerization + 50
                negative regulation of actin filament polymerization + 67
                negative regulation of actin nucleation + 9
                negative regulation of amyloid fibril formation 13
                negative regulation of cardiac myofibril assembly 1
                negative regulation of microtubule depolymerization + 39
                negative regulation of microtubule polymerization + 17
                negative regulation of myosin II filament organization + 0
                negative regulation of sarcomere organization 2
paths to the root