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ONTOLOGY REPORT - ANNOTATIONS


Term:thymic T cell selection
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Accession:GO:0045061 term browser browse the term
Definition:The process of T cell selection that occurs in the thymus.
Synonyms:exact_synonym: thymic T lymphocyte selection


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thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARD11 caspase recruitment domain family member 11 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr28:18,675,524...18,715,388 JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:14670303) MGI
Ensembl
PMID:14670303 GO_REF:0000107 NCBI chr 9:8,101,404...8,122,762
Ensembl chr 9:8,101,432...8,123,064
JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14517551) Ensembl
MGI
PMID:14517551 GO_REF:0000107 NCBI chr25:3,009,464...3,117,729
Ensembl chr25:3,009,353...3,118,235
JBrowse link
G JAG2 jagged canonical Notch ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:83,050,412...83,081,982
Ensembl chr24:83,051,368...83,076,820
JBrowse link
G LOC103241092 tyrosine-protein kinase ZAP-70 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9208839) Ensembl
MGI
PMID:9208839 GO_REF:0000107 NCBI chr14:1,403,294...1,430,205
Ensembl chr14:1,404,325...1,431,015
JBrowse link
G LOC103246958 caspase recruitment domain-containing protein 11 acts_upstream_of_or_within ISO (PMID:12867038) MGI PMID:12867038 NCBI chr28:18,657,941...18,714,202 JBrowse link
negative regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:71,302,082...71,400,201
Ensembl chr18:71,310,577...71,345,960
JBrowse link
negative thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIRE autoimmune regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23382543) Ensembl
MGI
PMID:23382543 GO_REF:0000107 NCBI chr 2:88,019,122...88,031,998
Ensembl chr 2:88,019,522...88,031,801
JBrowse link
G ATG5 autophagy related 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23382543) MGI
Ensembl
PMID:23382543 GO_REF:0000107 NCBI chr13:67,482,538...67,619,201
Ensembl chr13:67,482,595...67,617,902
JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:65,620,632...65,632,394
Ensembl chr16:65,620,665...65,632,984
JBrowse link
G CD28 CD28 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:10429671) MGI
Ensembl
PMID:10429671 GO_REF:0000107 NCBI chr10:89,471,710...89,505,152
Ensembl chr10:89,471,730...89,500,387
JBrowse link
G CD3E CD3e molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:7630421) MGI
Ensembl
PMID:7630421 GO_REF:0000107 NCBI chr 1:109,681,142...109,692,835
Ensembl chr 1:109,681,065...109,692,839
JBrowse link
G CD74 CD74 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:7679955) MGI
Ensembl
PMID:7679955 GO_REF:0000107 NCBI chr23:53,008,802...53,022,953
Ensembl chr23:53,009,394...53,022,923
JBrowse link
G DOCK2 dedicator of cytokinesis 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12871644) Ensembl
MGI
PMID:12871644 GO_REF:0000107 NCBI chr23:71,866,196...72,299,066
Ensembl chr23:71,866,251...72,299,056
JBrowse link
G GLI3 GLI family zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:16,386,700...16,665,648
Ensembl chr21:16,549,789...16,662,238
JBrowse link
G LOC103241092 tyrosine-protein kinase ZAP-70 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:7630421) Ensembl
MGI
PMID:7630421 GO_REF:0000107 NCBI chr14:1,403,294...1,430,205
Ensembl chr14:1,404,325...1,431,015
JBrowse link
G MINK1 misshapen like kinase 1 acts_upstream_of_or_within ISO (PMID:15608642) MGI PMID:15608642 NCBI chr16:4,305,680...4,370,554
Ensembl chr16:4,305,701...4,369,780
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:8666928) Ensembl
MGI
PMID:8666928 GO_REF:0000107 NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303
JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395
JBrowse link
G SPN sialophorin acts_upstream_of_or_within ISO (PMID:10429671) MGI PMID:10429671 NCBI chr 5:26,987,810...26,990,214 JBrowse link
positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1D CD1d molecule acts_upstream_of_or_within ISO (PMID:9133426) MGI PMID:9133426 NCBI chr20:5,726,307...5,733,355
Ensembl chr20:5,727,049...5,730,061
JBrowse link
G CD3D CD3d molecule involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 1:109,715,148...109,719,576
Ensembl chr 1:109,713,017...109,719,950
JBrowse link
G CD3E CD3e molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:109,681,142...109,692,835
Ensembl chr 1:109,681,065...109,692,839
JBrowse link
G CD3G CD3g molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:109,721,150...109,730,267
Ensembl chr 1:109,720,789...109,732,014
JBrowse link
G CD74 CD74 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9432982)
(PMID:7679955), (PMID:8598040)
MGI
Ensembl
PMID:7679955 PMID:8598040 PMID:9432982 GO_REF:0000107 NCBI chr23:53,008,802...53,022,953
Ensembl chr23:53,009,394...53,022,923
JBrowse link
G DOCK2 dedicator of cytokinesis 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12871644) Ensembl
MGI
PMID:12871644 GO_REF:0000107 NCBI chr23:71,866,196...72,299,066
Ensembl chr23:71,866,251...72,299,056
JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15064401) Ensembl
MGI
PMID:15064401 GO_REF:0000107 NCBI chr25:3,009,464...3,117,729
Ensembl chr25:3,009,353...3,118,235
JBrowse link
G LOC103241092 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:7630421) MGI
Ensembl
PMID:7630421 GO_REF:0000107 NCBI chr14:1,403,294...1,430,205
Ensembl chr14:1,404,325...1,431,015
JBrowse link
G MHC-DMA HLA class II histocompatibility antigen, DM alpha chain acts_upstream_of_or_within ISO (PMID:8598040)
(PMID:8638109)
(PMID:8598041), (PMID:9432982)
MGI PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982 NCBI chr17:39,142,340...39,151,804
Ensembl chr17:39,142,395...39,146,252
JBrowse link
G NFATC3 nuclear factor of activated T cells 3 involved_in ISO (PMID:17579027) UniProt PMID:17579027 NCBI chr 5:59,193,139...59,346,361 JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:8666928) Ensembl
MGI
PMID:8666928 GO_REF:0000107 NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303
JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395
JBrowse link
G SRF serum response factor acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:21098124) MGI
Ensembl
PMID:21098124 GO_REF:0000107 NCBI chr17:28,983,161...28,993,465
Ensembl chr17:28,983,002...28,992,995
JBrowse link
G STK11 serine/threonine kinase 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21487392) Ensembl
MGI
PMID:21487392 GO_REF:0000107 NCBI chr 6:973,033...996,857
Ensembl chr 6:974,144...995,136
JBrowse link
regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXN1 forkhead box N1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:22,291,597...22,306,977
Ensembl chr16:22,292,330...22,305,968
JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,777,490...55,086,819
Ensembl chr 8:54,776,015...54,927,091
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17043
    immune system process 2649
      T cell selection 65
        thymic T cell selection 28
          negative thymic T cell selection 13
          positive thymic T cell selection + 17
Path 2
Term Annotations click to browse term
  biological_process 17043
    developmental process 6815
      cellular developmental process 4563
        cell differentiation 4562
          cell development 3252
            hemopoiesis 1048
              leukocyte differentiation 679
                mononuclear cell differentiation 550
                  lymphocyte differentiation 450
                    T cell differentiation 335
                      T cell differentiation in thymus 110
                        thymic T cell selection 28
                          negative thymic T cell selection 13
                          positive thymic T cell selection + 17
paths to the root