Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:DNA damage response, signal transduction resulting in transcription
go back to main search page
Accession:GO:0042772 term browser browse the term
Definition:A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription.


show annotations for term's descendants           Sort by:
DNA damage response, signal transduction resulting in transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:10,436,532...10,454,023
Ensembl chr 1:11,654,963...11,661,526 		JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8738145) Ensembl
MGI		 PMID:8738145 GO_REF:0000107 NCBI chr13:13,574,422...13,658,967
Ensembl chr13:32,010,066...32,091,332 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10710310) Ensembl
MGI		 PMID:10710310 GO_REF:0000107 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599 		JBrowse link
G CHEK2 checkpoint kinase 2 acts_upstream_of_or_within ISO (PMID:10710310) MGI PMID:10710310 NCBI chr22:9,757,038...9,811,171 JBrowse link
G FOXM1 forkhead box M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:2,978,400...2,999,077
Ensembl chr12:2,910,028...2,930,503 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,071,118...61,078,667
Ensembl chr11:64,404,572...64,412,667 		JBrowse link
G RBM38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) UniProt PMID:17050675 NCBI chr20:53,731,641...53,749,688 JBrowse link
G RPS27L ribosomal protein S27 like involved_in ISO (PMID:18056458) UniProt PMID:18056458 NCBI chr15:42,101,137...42,105,019
Ensembl chr15:60,397,131...60,400,643 		JBrowse link
G RPS6KA6 ribosomal protein S6 kinase A6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:73,131,457...73,261,906
Ensembl chr  X:83,243,957...83,373,194 		JBrowse link
G TFAP4 transcription factor AP-4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:3,176,129...3,226,404
Ensembl chr16:4,348,929...4,368,525 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10710310) Ensembl
MGI		 PMID:10710310 GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCBP4 poly(rC) binding protein 4 acts_upstream_of_or_within ISO (PMID:20817677) MGI PMID:20817677 NCBI chr 3:51,898,857...51,908,932
Ensembl chr 3:53,127,448...53,137,293 		JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ING4 inhibitor of growth family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,782,402...6,795,035
Ensembl chr12:6,698,843...6,710,955 		JBrowse link
G LOC100977427 large ribosomal subunit protein uL24 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:56,616,749...56,617,299
Ensembl chr17:48,009,198...48,015,977 		JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:134,283,998...134,329,531
Ensembl chr 1:138,081,611...138,127,115 		JBrowse link
G RPL26 ribosomal protein L26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,274,839...43,282,606
Ensembl chr17:48,009,198...48,015,977 		JBrowse link
G ZNF385A zinc finger protein 385A involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:34,353,975...34,376,172
Ensembl chr12:35,080,820...35,102,248 		JBrowse link
G ZNHIT1 zinc finger HIT-type containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:93,359,038...93,365,521
Ensembl chr 7:106,599,579...106,606,157 		JBrowse link
regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COPS3 COP9 signalosome subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,013,180...34,047,546
Ensembl chr17:38,944,618...38,978,235 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    cellular process 16207
      signal transduction 5476
        intracellular signal transduction 2894
          signal transduction in response to DNA damage 184
            DNA damage response, signal transduction resulting in transcription 19
              DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator + 18
Path 2
Term Annotations click to browse term
  biological_process 16644
    biological regulation 11629
      regulation of biological process 11252
        signaling 5975
          signal transduction 5476
            intracellular signal transduction 2894
              signal transduction in response to DNA damage 184
                DNA damage response, signal transduction resulting in transcription 19
                  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator + 18
paths to the root