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ONTOLOGY REPORT - ANNOTATIONS

Term:foramen ovale closure
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Accession:GO:0035922 term browser browse the term
Definition:The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.
Synonyms:exact_synonym: foramen ovale of heart closure


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foramen ovale closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO MGI:2445238 (PMID:10969038) RGD PMID:10969038 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (PMID:19762328) RGD PMID:19762328 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure morphogenesis 2956
        foramen ovale closure 2
Path 2
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure development 6486
        multicellular organism development 5239
          system development 4526
            circulatory system development 1367
              heart development 740
                cardiac chamber development 202
                  cardiac septum development 130
                    cardiac septum morphogenesis 86
                      foramen ovale closure 2
paths to the root