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ONTOLOGY REPORT - ANNOTATIONS


Term:foramen ovale closure
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Accession:GO:0035922 term browser browse the term
Definition:The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.
Synonyms:exact_synonym: foramen ovale of heart closure


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foramen ovale closure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO MGI:2445238 (MGI:3639795|PMID:10969038) RGD PMID:10969038 MGI:3639795 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
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G Tbx20 T-box transcription factor 20 involved_in ISO (PMID:19762328) RGD PMID:19762328 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    developmental process 6769
      anatomical structure morphogenesis 2887
        foramen ovale closure 2
Path 2
Term Annotations click to browse term
  biological_process 19492
    developmental process 6769
      anatomical structure development 6195
        multicellular organism development 5632
          system development 5300
            animal organ development 4061
              heart development 696
                cardiac chamber development 200
                  cardiac septum development 130
                    cardiac septum morphogenesis 87
                      foramen ovale closure 2
paths to the root