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ONTOLOGY REPORT - ANNOTATIONS

Term:ABC-type sterol transporter activity
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Accession:GO:0034041 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out).
Synonyms:related_synonym: ATP-coupled sterol transmembrane transporter activity;   ATP-dependent sterol transmembrane transporter activity;   ATPase-coupled sterol transmembrane transporter activity;   sterol-transporting ATPase activity
 xref: Reactome:R-HSA-265783 "ABCG5:ABCG8 transports sterols from cytosol to extracellular region";   Reactome:R-HSA-5679101 "Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region";   Reactome:R-HSA-5679145 "Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region"


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ABC-type sterol transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 enables ISO
IBA		 (PMID:17408620)
GO_REF:0000033		 RGD
GO_Central		 PMID:17408620 GO_REF:0000033 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 enables ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:15210959)		 UniProt
Ensembl
GO_Central
RGD		 PMID:15210959 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20807
    transporter activity 1252
      transmembrane transporter activity 1152
        organic hydroxy compound transmembrane transporter activity 53
          ABC-type sterol transporter activity 2
Path 2
Term Annotations click to browse term
  molecular_function 20807
    transporter activity 1252
      transmembrane transporter activity 1152
        active transmembrane transporter activity 446
          primary active transmembrane transporter activity 153
            ATPase-coupled transmembrane transporter activity 118
              ATPase-coupled lipid transmembrane transporter activity 7
                ABC-type sterol transporter activity 2
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