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ONTOLOGY REPORT - ANNOTATIONS

Term:purine-rich negative regulatory element binding
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Accession:GO:0032422 term browser browse the term
Definition:Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.
Synonyms:broad_synonym: PNR element binding


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purine-rich negative regulatory element binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELK3 ETS transcription factor ELK3 enables IEA Ensembl GO_REF:0000107 NCBI chr12:93,781,034...93,863,042
Ensembl chr12:97,223,198...97,276,120 		JBrowse link
G PURA purine rich element binding protein A enables IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:135,541,865...135,610,526
Ensembl chr 5:141,659,224...141,727,870
Ensembl chr 5:141,659,224...141,727,870 		JBrowse link
G PURB purine rich element binding protein B enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 7:45,590,183...45,600,089
Ensembl chr 7:45,667,233...45,668,159 		JBrowse link
G PURG purine rich element binding protein G enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 8:30,315,336...30,353,180
Ensembl chr 8:27,503,358...27,540,290 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17686
    binding 16286
      organic cyclic compound binding 5337
        nucleic acid binding 3362
          transcription regulatory region nucleic acid binding 1307
            transcription cis-regulatory region binding 1302
              purine-rich negative regulatory element binding 4
Path 2
Term Annotations click to browse term
  molecular_function 17686
    binding 16286
      organic cyclic compound binding 5337
        nucleic acid binding 3362
          DNA binding 2180
            double-stranded DNA binding 1498
              sequence-specific double-stranded DNA binding 1407
                transcription cis-regulatory region binding 1302
                  purine-rich negative regulatory element binding 4
paths to the root