PURA (purine rich element binding protein A) - Rat Genome Database

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Gene: PURA (purine rich element binding protein A) Pan paniscus
Analyze
Symbol: PURA (Ensembl: CYSTM1)
Name: purine rich element binding protein A (Ensembl:cysteine rich transmembrane module containing 1)
RGD ID: 11881304
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN cell population proliferation (inferred); dendritic transport of messenger ribonucleoprotein complex (inferred); DNA unwinding involved in DNA replication (inferred); ASSOCIATED WITH Apnea (ortholog); autosomal dominant intellectual developmental disorder 31 (ortholog); Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (ortholog); FOUND IN cytoplasm (inferred); dendrite (inferred); glutamatergic synapse (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cysteine rich transmembrane module containing 1; cysteine-rich and transmembrane domain-containing protein 1; CYSTM1; transcriptional activator protein Pur-alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24135,367,844 - 135,434,934 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15133,507,397 - 133,566,974 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05135,541,865 - 135,610,526 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15141,659,224 - 141,727,870 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5141,659,224 - 141,727,870 (+)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl5141,598,580 - 141,599,762 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PURA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24135,367,844 - 135,434,934 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15133,507,397 - 133,566,974 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05135,541,865 - 135,610,526 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15141,659,224 - 141,727,870 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5141,659,224 - 141,727,870 (+)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl5141,598,580 - 141,599,762 (+)Ensemblpanpan1.1panPan2
PURA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385140,114,109 - 140,125,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5140,107,777 - 140,125,619 (+)EnsemblGRCh38hg38GRCh38
GRCh375139,493,694 - 139,505,204 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365139,473,892 - 139,476,505 (+)NCBINCBI36Build 36hg18NCBI36
Build 345139,473,891 - 139,475,030NCBI
Celera5135,569,524 - 135,572,137 (+)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5134,636,880 - 134,642,173 (+)NCBIHuRef
CHM1_15138,926,813 - 138,932,106 (+)NCBICHM1_1
T2T-CHM13v2.05140,639,205 - 140,650,714 (+)NCBIT2T-CHM13v2.0
Cystm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,481,677 - 36,536,032 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1836,475,573 - 36,536,150 (+)EnsemblGRCm39 Ensembl
GRCm381836,348,624 - 36,402,979 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,342,520 - 36,403,097 (+)EnsemblGRCm38mm10GRCm38
MGSCv371836,508,278 - 36,553,024 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361836,474,598 - 36,528,953 (+)NCBIMGSCv36mm8
Celera1836,804,473 - 36,849,164 (+)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.46NCBI
Cystm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81828,219,861 - 28,287,574 (+)NCBIGRCr8
mRatBN7.21827,945,862 - 28,013,509 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1827,951,653 - 28,013,510 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1828,079,115 - 28,140,687 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,840,959 - 28,902,773 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,175,881 - 28,238,020 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,165,206 - 29,233,351 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,191,731 - 29,232,978 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,872,838 - 28,939,398 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41828,984,344 - 29,031,445 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1827,676,564 - 27,742,217 (+)NCBICelera
Cytogenetic Map18p11NCBI
Cystm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955418415,703 - 475,796 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955418415,703 - 475,796 (-)NCBIChiLan1.0ChiLan1.0
CYSTM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,391,089 - 35,434,063 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,391,154 - 35,453,194 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,493,946 - 32,537,228 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0235,846,609 - 35,889,887 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl235,846,669 - 35,908,674 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1232,898,678 - 32,941,938 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0233,766,096 - 33,809,346 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,518,962 - 34,562,244 (+)NCBIUU_Cfam_GSD_1.0
Pura
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213152,471,846 - 152,488,693 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365319,129,715 - 9,130,515 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365319,129,024 - 9,134,916 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYSTM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2141,954,092 - 141,992,368 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12141,945,032 - 142,010,239 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22147,857,847 - 147,953,347 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYSTM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12342,826,312 - 42,891,610 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2342,826,337 - 42,891,871 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603434,993,814 - 35,058,828 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cystm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474332,965,527 - 33,011,361 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474332,965,075 - 33,011,472 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000039984   ⟹   ENSPPAP00000017282
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5141,659,224 - 141,727,870 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000062343   ⟹   ENSPPAP00000039432
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5141,598,580 - 141,599,762 (+)Ensembl
RefSeq Acc Id: XM_055113017   ⟹   XP_054968992
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24135,367,844 - 135,388,806 (+)NCBI
NHGRI_mPanPan15133,507,397 - 133,528,358 (+)NCBI
RefSeq Acc Id: XM_055113018   ⟹   XP_054968993
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24135,367,844 - 135,388,806 (+)NCBI
NHGRI_mPanPan15133,507,397 - 133,528,358 (+)NCBI
RefSeq Acc Id: XM_055113019   ⟹   XP_054968994
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24135,373,339 - 135,388,806 (+)NCBI
NHGRI_mPanPan15133,512,900 - 133,528,358 (+)NCBI
RefSeq Acc Id: XR_008625509
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24135,367,976 - 135,427,423 (+)NCBI
NHGRI_mPanPan15133,507,706 - 133,566,974 (+)NCBI
RefSeq Acc Id: XR_010112130
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24135,367,976 - 135,434,934 (+)NCBI
Protein Sequences
Protein RefSeqs XP_054968992 (Get FASTA)   NCBI Sequence Viewer  
  XP_054968993 (Get FASTA)   NCBI Sequence Viewer  
  XP_054968994 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000039432.1
Ensembl Acc Id: ENSPPAP00000017282   ⟸   ENSPPAT00000039984
Ensembl Acc Id: ENSPPAP00000039432   ⟸   ENSPPAT00000062343
RefSeq Acc Id: XP_054968992   ⟸   XM_055113017
RefSeq Acc Id: XP_054968993   ⟸   XM_055113018
RefSeq Acc Id: XP_054968994   ⟸   XM_055113019


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031723 Ensembl, ENTREZGENE
  ENSPPAG00000042421 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062343.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.450.700 UniProtKB/TrEMBL
  3.30.2450.30 UniProtKB/TrEMBL
InterPro PUR-bd_fam UniProtKB/TrEMBL
NCBI Gene CYSTM1 ENTREZGENE
PANTHER PTHR12611 UniProtKB/TrEMBL
  PTHR12611:SF2 UniProtKB/TrEMBL
Pfam PurA UniProtKB/TrEMBL
SMART PUR UniProtKB/TrEMBL
UniProt A0A2R9CMS8_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 PURA  purine rich element binding protein A  CYSTM1  cysteine rich transmembrane module containing 1  Symbol and/or name change 5135510 APPROVED
2023-04-20 CYSTM1  cysteine rich transmembrane module containing 1  PURA  purine rich element binding protein A  Data merged from RGD:11942846 737654 PROVISIONAL